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Theileria parva is the etiologic agent of East Coast fever, an economically important disease of cattle in sub-Saharan Africa. This protozoan parasite is biologically transmitted by Rhipicephalus appendiculatus (Neumann) (Acari: Ixodidae). An understanding of the vector—parasite interaction may a...


Odongo, David O.Ueti, M.W.Mwaura, S.N.Knowles, Donald P.Bishop, Richard P.Scoles, Glen A.[Quantification of Theileria parva in Rhipicephalus appendiculatus (Acari: Ixodidae) Confirms differences in infection between selected tick strains]Quantification of Theileria parva in Rhipicephalus appendiculatus (Acari: Ixodidae) Confirms differences in infection between selected tick strains

Viral enteritis is a serious problem accounting for deaths in neonatal animals and humans worldwide. The absence of surveillance programs and diagnostic laboratory facilities have resulted in a lack of data on rotavirus associated diarrheas in pigs in East Africa. Here we describe the incidence o...


Amimo, Joshua O.Jung'a, J.O.Ogara, W.O.Vlasova, A.N.Njahira, Moses N.Maina, S.Okoth, Edward A.Bishop, Richard P.Saif, L.J.Djikeng, Appolinaire[Detection and genetic characterization of porcine group A rotaviruses in asymptomatic pigs in smallholder farms in East Africa: Predominance of P[8] genotype resembling human strains]Detection and genetic characterization of porcine group A rotaviruses in asymptomatic pigs in smallholder farms in East Africa: Predominance of P[8] genotype resembling human strains

Bishop, Richard P.[Understanding the epidemiology of African swine fever (ASF) to support development of evidence-based control strategies]Understanding the epidemiology of African swine fever (ASF) to support development of evidence-based control strategies
Okoth, Edward A.Macharia, J.M.Omore, Amos O.Pelayo, V.Bulimo, WallaceArias, MarisaKitala, P.Lekolol, I.Mijele, D.Bishop, Richard P.[An African swine fever virus genotype present in both the resistant bushpig (Potamochoerus larvatus) and adjacent domestic pig populations does not induce detectable clinical ASF symptoms]An African swine fever virus genotype present in both the resistant bushpig (Potamochoerus larvatus) and adjacent domestic pig populations does not induce detectable clinical ASF symptoms
Bishop, Richard P.Musoke, A.J.Skilton, Robert A.Morzaria, S.P.Gardner, M.Nene, Vishvanath[Theileria: Life cycle stages associated with the ixodid tick vector]Theileria: Life cycle stages associated with the ixodid tick vector
Bishop, Richard P.Odongo, David O.Mann, D.J.Pearson, T.W.Sugimoto, C.Haines, L.R.Glass, E.Jensen, K.Seitzer, U.Ahmed, J.S.Graham, S.P.Villiers, Etienne P. de[Theileria]Theileria
Bishop, Richard P.Musoke, A.J.Skilton, Robert A.Odongo, D.Scoles, Glen A.Knowles, D.Nene, Vishvanath[Approaches to improved understanding of vector parasite interaction within the genus Theileria and their Ixodid tick vectors]Approaches to improved understanding of vector parasite interaction within the genus Theileria and their Ixodid tick vectors

Polymorphic, multicopy gene families are frequently located in subtelomeric regions of the genomes of parasitic protozoa. Theileria parva telomere-associated (TA) DNA from two chromosomes contained long open reading frames (ORFs) 54% identical at the N-termini whose ends were 2670 and 2680 bp fro...


Bishop, Richard P.Gobright, E.I.Nene, VishvanathMorzaria, S.P.Musoke, A.J.Sohanpal, B.K.[Polymorphic open reading frames encoding secretory proteins are located less than 3 kilobases from Theileria parva telomeres]Polymorphic open reading frames encoding secretory proteins are located less than 3 kilobases from Theileria parva telomeres

Theileria are economically important, intra-cellular protozoa, transmitted by ixodid ticks, which infect wild and domestic ruminants. In the mammalian host, parasites infect leukocytes and erythrocytes. In the arthropod vector they develop in gut epithelial cells and salivary glands. All four int...


Bishop, Richard P.Musoke, A.J.Morzaria, S.P.Gardner, M.Nene, Vishvanath[Theileria: Intracellular protozoan parasites of wild and domestic ruminants transmitted by ixodid ticks]Theileria: Intracellular protozoan parasites of wild and domestic ruminants transmitted by ixodid ticks

As a first step in developing compartment-specific markers for protein trafficking within Theileria parva, we have isolated cDNAs encoding homologues of the small GTP binding proteins Rab1 and Rab4. The T. parva homologue of Rab1 (TpRab1), a protein which regulates vesicular transport between the...


Janoo, R.T.K.Musoke, A.J.Wells, C.Bishop, Richard P.[A Rab1 homologue with a novel isoprenylation signal provides insight into the secretory pathway of Theileria parva]A Rab1 homologue with a novel isoprenylation signal provides insight into the secretory pathway of Theileria parva

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