From a lysate of radiolabeled Theileria parva-infected bovine lymphocytes monoclonal antibody (mAb) IL-A77 immunoprecipitated a molecule of Mr 190 000 under non-reducing conditions, which was shown to be a homodimer of a Mr 90 000 protein after reduction (Naessens et al., 1996). Purification of t...
Naessens, Jan
,
Sileghem, M.R.
,
MacHugh, Niall D.
,
Park, Y.H.
,
Davis, W.C.
,
Toye, Philip G.
,
[Selection of BoCD25 monoclonal antibodies by screening mouse L cells transfected with the bovine p55-interleukin-2 (IL-2) receptor gene]
,
Selection of BoCD25 monoclonal antibodies by screening mouse L cells transfected with the bovine p55-interleukin-2 (IL-2) receptor gene
In this report, we describe the cloning, sequencing, and expression of the bovine orthologue of CD26 (BoCD26). Several monoclonal antibodies specific for a molecule, activation molecule 3 (ACT3), aberrantly expressed on superantigen-stimulated bovine CD8+ lymphocytes, reacted with recombinant BoC...
Sang-Un Lee
,
Young-Ho Park
,
Davis, W.C.
,
Hamilton, M. Jo
,
Naessens, Jan
,
Bohach, G.A.
,
[Molecular characterization of bovine CD26 upregulated by a staphylococcal superantigen]
,
Molecular characterization of bovine CD26 upregulated by a staphylococcal superantigen
Ellis, J.A.
,
Scott, J.R.
,
MacHugh, Niall D.
,
Gettinby, G.
,
Davis, W.C.
,
[Peripheral blood leukocyte subpopulation dynamics during Trypanosoma congolense infection in Boran and N'Dama cattle. An analysis using monoclonal antibodies and flow cytometry]
,
Peripheral blood leukocyte subpopulation dynamics during Trypanosoma congolense infection in Boran and N'Dama cattle. An analysis using monoclonal antibodies and flow cytometry
T cells bearing the gamma delta antigen receptor (gamma delta T cells) can constitute up to 50 percent of T cells in the peripheral blood and lymphoid organs of young cattle. We present data showing that gamma delta T cells are involved in immune responses against Theileria parva. Gamma delta T c...
Daubenberger, C.A.
,
Taracha, E.L.N.
,
Gaidulis, L.
,
Davis, W.C.
,
McKeever, Declan J.
,
[Bovine gamma delta T cell responses to the intracellular protozoan parasite Theileria parva]
,
Bovine gamma delta T cell responses to the intracellular protozoan parasite Theileria parva
We describe the characterization of two subsets of bovine gamma delta T cells having distinct cell surface phenotype and tissue distribution. One population expresses the previously described 215000 MW WC1 antigen and is negative for the cell-surface differentiation antigens CD2. CD4, and CD8. Th...
MacHugh, Niall D.
,
Mburu, J.K.
,
Carol, M.J.
,
Wyatt, C.R.
,
Orden, J.A.
,
Davis, W.C.
,
[Identification of two distinct subsets of gamma/delta T cells with unique cell surface phenotype and tissue distribution]
,
Identification of two distinct subsets of gamma/delta T cells with unique cell surface phenotype and tissue distribution
Davis, W.C.
,
Ellis, J.A.
,
MacHugh, Niall D.
,
Baldwin, C.L.
,
[Bovine pan T-cell monoclonal antibodies reactive with a molecule similar to CD2]
,
Bovine pan T-cell monoclonal antibodies reactive with a molecule similar to CD2
MacHugh, Niall D.
,
Bensaid, A.M.
,
Davis, W.C.
,
Howard, C.J.
,
Parsons, K.R.
,
Jones, B.
,
Kaushal, A.
,
[Characterization of a bovine thymic differentiation antigen analogous to CD1 in the human]
,
Characterization of a bovine thymic differentiation antigen analogous to CD1 in the human
Alpha gamma T cells in ruminants can be subdivided in two or more subpopulations on the basis of the expression of surface antigen WC1, which can exist in different isoforms. In this study, 18 monoclonal antibodies (mAbs) submitted to the Third International Workshop that were predicted to react ...
Davis, W.C.
,
Brown, W.C.
,
Hamilton, M.J.
,
Wyatt, C.R.
,
Orden, J.A.
,
Khalid, A.M.
,
Naessens, Jan
,
[Analysis of monoclonal antibodies specific for the gamma alpha TcR]
,
Analysis of monoclonal antibodies specific for the gamma alpha TcR