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Eisler, M.C.Arowolo, R.O.A.Gault, E.A.Moloo, S.K.Holmes, P.H.Peregrine, A.S.[Isometamidium concentrations in the sera of Boran cattle. Correlation with prophylaxis against tsetse-transmitted Trypanosoma congolense]Isometamidium concentrations in the sera of Boran cattle. Correlation with prophylaxis against tsetse-transmitted Trypanosoma congolense

Cattle from 50 farms in Mukono County, Uganda, were monitored for trypanosomes every second month over an 18-month period (1995–1996) by mini-anion exchange chromatography and haematocrit centrifugation techniques. Eighteen trypanosome isolates collected from cattle during this period were charac...


Olila, D.McDermott, John J.Eisler, M.C.Mitema, E.S.Patzelt, R.J.Clausen, P.H.Poetzsch, C.J.Zessin, K.H.Mehlitz, D.Peregrine, A.S.[Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda]Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda
Machila, N.Fèvre, Eric M.Maudlin, I.Eisler, M.C.[Farmer estimation of live bodyweight of cattle: Implications for veterinary drug dosing in East Africa]Farmer estimation of live bodyweight of cattle: Implications for veterinary drug dosing in East Africa
Picozzi, K.Fèvre, Eric M.Odiit, M.Carrington, M.Eisler, M.C.Maudlin, I.[Sleeping sickness in Uganda: A thin line between two fatal diseases]Sleeping sickness in Uganda: A thin line between two fatal diseases

Sensitivity and specificity of the FAO/IAEA kits for diagnosis of bovine trypanosomosis were investigated using sera from experimental cattle infected by tsetse challenge with cloned populations of Trypanosoma congolense (three populations) or T. vivax (one population). The kits are based on mono...


Eisler, M.C.Lessard, P.Masake, R.A.Moloo, S.K.Peregrine, A.S.[Sensitivity and specificity of antigen-capture ELISAs for diagnosis of Trypanosoma congolense and Trypansoma vivax infections in cattle]Sensitivity and specificity of antigen-capture ELISAs for diagnosis of Trypanosoma congolense and Trypansoma vivax infections in cattle

A survey to investigate resistance to drugs used in the treatment of bovine trypanosomosis was conducted in the eastern province of Zambia between 1996 and 1998. A cross-sectional study was conducted in three districts (Petauke, Katete, Lundazi) at 34 village sampling sites selected at random fr...


Sinyangwe, L.Delespaux, V.Brandt, J.Geerts, S.Mubanga, J.Machila, N.Holmes, P.H.Eisler, M.C.[Trypanocidal drug resistance in eastern province of Zambia]Trypanocidal drug resistance in eastern province of Zambia

In a tsetse-infested area of Kenya, we characterised veterinary-drug outlets based on personnel and business characteristics to assess their capacities to provide clinical veterinary services. Structured questionnaires were administered to the retailers and sought information on the characterist...


Bett, Bernard K.Machila, N.Gathura, P.B.McDermott, John J.Eisler, M.C.[Characterisation of shops selling veterinary medicines in a tsetse-infested area of Kenya]Characterisation of shops selling veterinary medicines in a tsetse-infested area of Kenya

Mice were immunized with either an isometamidium-human serum albumin (HSA) conjugate or an isometamidium-porcine thyroglobulin conjugate (PTG). Thereafter, monoclonal antibodies (MAbs) IL-A 1001, IL-A 1002, IL-A 1003, 5F7.B7, and 5F7.C9 were generated and selected on the basis that they recognize...


Peregrine, A.S.Eisler, M.C.Katende, J.Flynn, J.N.Gault, E.A.Kinabo, L.D.B.Holmes, P.H.[Generation of monoclonal antibodies to the anti-trypanosomal drug isometamidium]Generation of monoclonal antibodies to the anti-trypanosomal drug isometamidium

The relationship between serum concentrations of the prophylactic trypanocidal drug isometamidium chloride and protection against tsetse challenge with two populations of Trypanosoma congolense was investigated in Boran (Bos indicus) cattle, using an isometamidium-ELISA. Isometamidium chloride (S...


Eisler, M.C.Gault, E.A.Moloo, S.K.Holmes, P.H.Peregrine, A.S.[Concentrations of isometamidium in the sera of cattle challenged with drug-resistant Trypanosoma congolense]Concentrations of isometamidium in the sera of cattle challenged with drug-resistant Trypanosoma congolense

Background Human brucellosis has been found to be prevalent in the urban areas of Kampala, the capital city of Uganda. A cross-sectional study was designed to generate precise information on the prevalence of brucellosis in cattle and risk factors for the disease in its urban and peri-urban dairy...


Makita, K.Fèvre, Eric M.Waiswa, C.Eisler, M.C.Thrusfield, M.V.Welburn, S.C.[Herd prevalence of bovine brucellosis and analysis of risk factors in cattle in urban and peri-urban areas of the Kampala economic zone, Uganda]Herd prevalence of bovine brucellosis and analysis of risk factors in cattle in urban and peri-urban areas of the Kampala economic zone, Uganda

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