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Izquierdo, GianninaGarcia, PatriciaAravena, MartaDelpiano, LuisReyes, AlejandraCofre, FernandaHernandez, MariluzSandoval, AlejandraLabrana, Yenis[Blood cultures in newborns: optimizing sample collection and performance]Blood cultures in newborns: optimizing sample collection and performance

Holm-Nielsen, Lauritz B.Blom, AndreasGarcia, Patricia[ Providing Skills for the Knowledge Economy : The World Bank in Tertiary Education in Latin America and the Caribbean , Como procurar las capacidades necesarias para la economdel conocimiento : el Banco Mundial en la educacion terciaria de America Latina y el Caribe ]

Signaling pathway alterations are important in the development of gastric cancer (GC). Deregulation of the PI3K/AKT/mTOR pathway plays a crucial role in the regulation of multiple cellular functions including cell growth, proliferation, metabolism, and angiogenesis. Our goal was to assess express...


Tapia, OscarRiquelme, IsmaelLeal, PamelaSandoval, AlejandraAedo, SusanaWeber, HelgaLetelier, PabloBellolio, EnriqueVillaseca, MiguelGarcia, PatriciaCarlos Roa, Juan[The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significance]The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significance

Overexpression of Short and Raji variants of Cellular FLICE-like inhibitory protein (c-FLIP) is capable of inhibiting apoptosis, while the function of the Long isoform depends of c-FLIPL concentration in cells. The aim of this study was to determine the effects of c-FLIPL knockdown in cervical ce...


Ili, Carmen G.Brebi, PriscillaGarcia, PatriciaLeal, PamelaLopez, JaimeTapia, OscarLetelier, PabloWeber, HelgaCastillo, JonathanRoa, Juan C.[Effects of c-FLIPL Knockdown in Cervical Uterine Carcinoma Cell Lines]Effects of c-FLIPL Knockdown in Cervical Uterine Carcinoma Cell Lines

The development of miRNA-based therapeutics represents a new strategy in cancer treatment. The objectives of this study were to evaluate the differential expression of microRNAs in gallbladder cancer (GBC) and to assess the functional role of miR-1 and miR-145 in GBC cell behavior. A profile of m...


Letelier, PabloGarcia, PatriciaLeal, PamelaAlvarez, HectorIli, CarmenLopez, JaimeCastillo, JonathanBrebi, PriscillaRoa, Juan Carlos[miR-1 and miR-145 act as tumor suppressor microRNAs in gallbladder cancer]miR-1 and miR-145 act as tumor suppressor microRNAs in gallbladder cancer

Aims Gallbladder cancer (GBC) is an aggressive tumour that is usually diagnosed at advanced stages and is characterised by a poor prognosis. Using public data of normal human tissues, we found that mRNA and protein levels of mucin 5B (MUC5B) and carbonic anhydrase 9 (CA9) were highly increased in...


Espinoza, Jaime A.Riquelme, IsmaelSagredo, Eduardo A.Rosa, LorenaGarcia, PatriciaBizama, CarolinaApud Bell, MariaLeal, PamelaWeber, HelgaBenavente Muñoz, FelipeVargas, SergioRomero, DiegoKalergis, Alexis M.Carlos Roa, Juan[Mucin 5B, carbonic anhydrase 9 and claudin 18 are potential theranostic markers of gallbladder carcinoma]Mucin 5B, carbonic anhydrase 9 and claudin 18 are potential theranostic markers of gallbladder carcinoma

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