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Salp15, a 15-kDa tick salivary gland protein, has several suppressive modes of activity against host immunity and plays a critical role in the transmission of Lyme disease spirochetes in Ixodes scapularis and Ixodes ricinus, major vectors of Lyme disease in North America and Western Europe. Salp1...


Murase, Y.Konnai, S.Yamada, S.Githaka, Naftaly W.Isezaki, M.Ito, T.Takano, A.Ando, S.Kawabata, H.Murata, S.Ohashi, K.[An investigation of binding ability of Ixodes persulcatus Schulze Salp15 with Lyme disease spirochetes]An investigation of binding ability of Ixodes persulcatus Schulze Salp15 with Lyme disease spirochetes

Ixodes ricinus immunosuppressor (Iris) is a tick salivary gland protein derived from I. ricinus. In this study, Iris homolog was identified in the salivary glands of Ixodes persulcatus, which is the specific vector of the Lyme disease agent in Japan. The homolog was named Ipis-1. To investigate t...


Toyomane, K.Konnai, S.Niwa, A.Githaka, Naftaly W.Isezaki, M.Yamada, S.Ito, T.Takano, A.Ando, S.Kawabata, H.Murata, S.Ohashi, K.[Identification and the preliminary in vitro characterization of IRIS homologue from salivary glands of Ixodes persulcatus Schulze]Identification and the preliminary in vitro characterization of IRIS homologue from salivary glands of Ixodes persulcatus Schulze

Background Although vector control strategies, such as insecticide-treated bed nets (ITNs) and indoor residual spraying (IRS) have been effective in Kenya the transmission of malaria continues to afflict western Kenya. This residual transmission is driven in part by Anopheles arabiensis, known fo...


Lozano-Fuentes, SaulKading, R.C.Hartman, D.A.Okoth, Edward A.Githaka, Naftaly W.Nene, VishvanathPoche, R.M.[Evaluation of a topical formulation of eprinomectin against Anopheles arabiensis when administered to Zebu cattle (Bos indicus) under field conditions]Evaluation of a topical formulation of eprinomectin against Anopheles arabiensis when administered to Zebu cattle (Bos indicus) under field conditions
Silatsa, Barberine A.Simo, GustaveGithaka, Naftaly W.Mwaura, StephenKamga, Rolin M.Oumarou, FariikouTiambo, Christian K.Bishop, Richard P.Djikeng, AppolinaireKuiate, Jules-RogerNjiokou, FlobertPelle, Roger[A comprehensive survey of the prevalence and spatial distribution of ticks infesting cattle in different agro-ecological zones of Cameroon]A comprehensive survey of the prevalence and spatial distribution of ticks infesting cattle in different agro-ecological zones of Cameroon

Domelevo Entfellner, Jean-BakaNene, VishvanathSteinaa, LucillaOkoth, Edward A.Ouma, Emily A.Lacasta, AnnaGithaka, Naftaly W.[Pig value chain and African swine fever mitigation: A call to rally cross-program collaboration]Pig value chain and African swine fever mitigation: A call to rally cross-program collaboration

Githaka, Naftaly W.Mwaura, S.Nene, Vishvanath[ILRI Tick Unit: Local research with global impact]ILRI Tick Unit: Local research with global impact

Githaka, Naftaly W.Nene, VishvanathBishop, Richard P.[Report from an ILRI strategy workshop on tick research, Cape Town, 24 August 2014]Report from an ILRI strategy workshop on tick research, Cape Town, 24 August 2014
Silatsa, Barberine A.Kuiate, Jules-RogerNjiokou, F.Simo, G.Feussom, J.-M.K.Tunrayo, A.Amzati, Gaston S.Bett, Bernard K.Bishop, R.Githaka, Naftaly W.Opiyo, S.O.Djikeng, AppolinairePelle, Roger[A countrywide molecular survey leads to a seminal identification of the invasive cattle tick Rhipicephalus (Boophilus) microplus in Cameroon, a decade after it was reported in Cote d’Ivoire]A countrywide molecular survey leads to a seminal identification of the invasive cattle tick Rhipicephalus (Boophilus) microplus in Cameroon, a decade after it was reported in Cote d’Ivoire

The transcriptional control of gene expression is not well documented in the Arthropoda. We describe transcriptional analysis of two exceptionally divergent homologues (Ra86) of the Bm86 gut antigen from Rhipicephalus appendiculatus. Bm86 forms the basis of a commercial vaccine for the control of...


Kamau, L.Skilton, Robert A.Odongo, David O.Mwaura, S.Githaka, Naftaly W.Kanduma, E.G.Obura, M.Kabiru, E.Orago, A.Musoke, A.J.Bishop, Richard P.[Differential transcription of two highly divergent gut-expressed Bm86 antigen gene homologues in the tick Rhipicephalus appendiculatus (Acari: Ixodida)]Differential transcription of two highly divergent gut-expressed Bm86 antigen gene homologues in the tick Rhipicephalus appendiculatus (Acari: Ixodida)

Background The ixodid tick Rhipicephalus appendiculatus transmits the apicomplexan protozoan parasite Theileria parva,which causes East coast fever (ECF), the most economically important cattle disease in eastern and southern Africa. Recent analysis of micro- and minisatellite markers showed an a...


Kanduma, E.G.Mwacharo, Joram M.Githaka, Naftaly W.Kinyanjui, P.W.Njuguna, J.Kamau, L.M.Kariuki, E.Mwaura, S.Skilton, Robert A.Bishop, Richard P.[Analyses of mitochondrial genes reveal two sympatric but genetically divergent lineages of Rhipicephalus appendiculatus in Kenya]Analyses of mitochondrial genes reveal two sympatric but genetically divergent lineages of Rhipicephalus appendiculatus in Kenya

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