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Abstract Background In the adult central nervous system (CNS), Wnt signaling regulates dendritic structure and synaptic plasticity. The Wnt signaling pathway can be divided into the canonical (β-catenin-dependent) and non-canonical pathways. In the c...


Ríos Leal, Juvenal Antonio.Godoy Zeballos, Juan Alejandro.Inestrosa Cantín, Nibaldo.[Wnt3a ligand facilitates autophagy in hippocampal neurons by modulating a novel GSK-3β-AMPK axis]Wnt3a ligand facilitates autophagy in hippocampal neurons by modulating a novel GSK-3β-AMPK axis

Abstract Background Soluble amyloid-β (Aβ;) oligomers have been recognized to be early and key intermediates in Alzheimer's disease (AD)-related synaptic dysfunction. Aβ oligomers block hippocampal long-term potentiation (LTP) and impair rodent spati...


Cerpa Nebott, Waldo Francisco.Farías Galdames, Ginny Cheryl.Godoy Zeballos, Juan Alejandro.Inestrosa Cantín, Nibaldo.Fuenzalida, Marco.Bonansco, Christian.[Wnt-5aoccludes Aβ oligomer-induced depression of glutamatergic transmission in hippocampal neurons]Wnt-5aoccludes Aβ oligomer-induced depression of glutamatergic transmission in hippocampal neurons

Godoy Zeballos, Juan Alejandro.Inestrosa Cantín, Nibaldo.[Role of Sirt1 During the Ageing Process: Relevance to Protection of Synapses in the Brain]Role of Sirt1 During the Ageing Process: Relevance to Protection of Synapses in the Brain

Codocedo Henríquez, Juan Francisco.Godoy Zeballos, Juan Alejandro.Inestrosa Cantín, Nibaldo.[ATP Induces NO Production in Hippocampal Neurons by P2X(7) Receptor Activation Independent of Glutamate Signaling]ATP Induces NO Production in Hippocampal Neurons by P2X(7) Receptor Activation Independent of Glutamate Signaling

Quintanilla Gómez, Rodrigo Arthur.Bernhardi Montgomery, Rommy von.Godoy Zeballos, Juan Alejandro.Inestrosa Cantín, Nibaldo.[Phosphorylated tau potentiates A beta-induced mitochondrial damage in mature neurons]Phosphorylated tau potentiates A beta-induced mitochondrial damage in mature neurons

Godoy Zeballos, Juan Alejandro.Ríos Leal, Juvenal Antonio.Inestrosa Cantín, Nibaldo.[Signaling pathway cross talk in Alzheimer's disease]Signaling pathway cross talk in Alzheimer's disease

Cerpa Nebott, Waldo FranciscoFarías Galdames, Ginny Cheryl.Godoy Zeballos, Juan Alejandro.Inestrosa Cantín, Nibaldo.[Wnt-5a occludes A beta oligomer-induced depression of glutamatergic transmission in hippocampal neurons]Wnt-5a occludes A beta oligomer-induced depression of glutamatergic transmission in hippocampal neurons

Silva Alvarez, Carmen.Arrazola Tello, Macarena Soledad.Godoy Zeballos, Juan Alejandro.Inestrosa Cantín, Nibaldo.[Canonical Wnt signaling protects hippocampal neurons from A beta oligomers: role of non-canonical Wnt-5a/Ca2+ in mitochondrial dynamics]Canonical Wnt signaling protects hippocampal neurons from A beta oligomers: role of non-canonical Wnt-5a/Ca2+ in mitochondrial dynamics

Godoy Zeballos, Juan Alejandro.Arrazola Tello, Macarena Soledad.Inestrosa Cantín, Nibaldo.[Wnt-5a Ligand Modulates Mitochondrial Fission-Fusion in Rat Hippocampal Neurons]Wnt-5a Ligand Modulates Mitochondrial Fission-Fusion in Rat Hippocampal Neurons

Ill-Raga, G.Godoy Zeballos, Juan Alejandro.Belmar Lucero, Sebastián Antoni.Cerpa Nebott, Waldo Francisco.[Amyloid-beta Peptide Fibrils Induce Nitro-Oxidative Stress in Neuronal Cells]Amyloid-beta Peptide Fibrils Induce Nitro-Oxidative Stress in Neuronal Cells

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