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East coast fever (ECF) is a major tick-borne disease caused by the apicomplexan parasite Theileria parva (1). ECF is an acute leukemia-like disease of cattle that is endemic in eastern, central and souther Africa, where it is responsible for significant mortality and losses in animal production. ...
Various parasitic protozoa of the family Trypanosomatidae such as Crithidia spp. [1]; Trypanosoma cruzi [2]; Leishmania donovani [3] and salivarian trypanosomes [4-8] have been shown to contain acid phosphatase activity (EC.3.1.3.2, orthophosphoric-monoester phosphohydrolase activity). Acid phosp...
The membrane-associated form of the variable surface glycoprotein (mfVSG) from African trypanosomes is a potent macrophage activator capable of inducing production of tumor necrosis factor z (TNFalfa) in both bovine and murine models. Using a bovine model. we have re-investigated the hypothesis t...
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