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Lawal, R.A.Al-Atiyat, R.M.Aljumaah, R.S.Silva, P.Mwacharo, Joram M.Hanotte, Olivier H.[Whole-genome resequencing of red junglefowl and indigenous village chicken reveal new insights on the genome dynamics of the species]Whole-genome resequencing of red junglefowl and indigenous village chicken reveal new insights on the genome dynamics of the species
Aguiar, T.S.Torrecilha, R.B.P.Milanesi, M.Utsunomiya, A.T.H.Trigo, B.B.Tijjani, A.Musa, H.H.Lopes, F.L.Ajmone-Marsan, P.Carvalheiro, R.Neves, H.H.R.Carmo, A.S. doHanotte, Olivier H.Sonstegard, T.S.García, J.F.Utsunomiya, Yuri Tani[Association of copy number variation at Intron 3 of HMGA2 with navel length in Bos indicus]Association of copy number variation at Intron 3 of HMGA2 with navel length in Bos indicus

Indigenous goat breeds kept by majority of smallholder rural farmers in Eastern Africa are adapted to the local environment. These goats are critical for nutrition and income of their keepers. Milk production per doe is extremely variable. The variation in milk yield in goats is due to varied man...


Kiplagat, S.K.Agaba, MorrisKosgey, I.S.Okeyo Mwai, AllyIndetie, D.Hanotte, Olivier H.Limo, M.K.H.[Genetic polymorphism of kappa-casein gene in indigenous Eastern Africa goat populations]Genetic polymorphism of kappa-casein gene in indigenous Eastern Africa goat populations

A preliminary search for QTLs in a cattle F2 resource populations segregating for trypanotolerance has revealed three large candidate chromosomal regions (Bta02, Bta05, Bta07). In order to narrow down the position of the trypanotolerant QTLs, we are building comparative chromosomal maps between c...


Nilsson, P.H.Kang'a, S.Rottengatter, K.Suedbeck, U.Iraqui, F.Mwakaya, J.Mwangi, D.Womack, J.E.Goldammer, T.Schwerin, M.Bradley, D.Agaba, MorrisSugimoto, K.Gelhaus, A.Horstmann, R.Teale, A.J.Kemp, Stephen J.Hanotte, Olivier H.[Radiation hybrid maps of candidate trypanotolerance regions in cattle]Radiation hybrid maps of candidate trypanotolerance regions in cattle

We have sought to test the possibility of detecting regions of the genome under selection through effects on variation at linked neutral genetic markers. Particularly, we investigated three genomic regions identified by mapping in a cross-bred pedigree as harbouring QTL for trypanosomiasis tolera...


Park, S.D.E.Adomefa, K.Dao, B.Hanotte, Olivier H.Kemp, Stephen J.Sow, R.S.Teale, A.J.Bradley, D.G.[Application of population genetic analysis of linked, mapped microsatellites to the identification of loci under selection for disease resistance]Application of population genetic analysis of linked, mapped microsatellites to the identification of loci under selection for disease resistance

Background: The history of African indigenous cattle and their adaptation to environmental and human selection pressure is at the root of their remarkable diversity. Characterization of this diversity is an essential step towards understanding the genomic basis of productivity and adaptation to s...


Kim, JaeminHanotte, Olivier H.Okeyo Mwai, AllyDessie, TadelleSalim, BashirDiallo, BoubacarAgaba, MorrisKwondo KimWoori KwakSamsun SungSeo, MinseokJeong, HyeonsooKwon, TaehyungTaye, MengistieSong, Ki-DukLim, DajeongSeoae ChoLee, Hyun-JeongDuhak YoonSung Jong OhKemp, Stephen J.Hak-Kyo LeeHeebal Kim[The genome landscape of indigenous African cattle]The genome landscape of indigenous African cattle

Pigmentation in mammals is primarily determined by the distribution of eumelanin and pheomelanin, the ratio of which is mostly controlled by the activity of melanocortin 1 receptor (MC1R) and agouti signaling protein (ASIP) genes. Using 91 animals from 10 Arabian camel populations, that included ...


Almathen, FaisalElbir, HaithamBahbahani, HussainMwacharo, Joram M.Hanotte, Olivier H.[Polymorphisms in MC1R and ASIP Genes are associated with Coat Color Variation in the Arabian Camel]Polymorphisms in MC1R and ASIP Genes are associated with Coat Color Variation in the Arabian Camel

Many individual hosts are infected with multiple parasite species, and this may increase or decrease the pathogenicity of the infections. This phenomenon is termed heterologous reactivity and is potentially an important determinant of both patterns of morbidity and mortality and of the impact of ...


Woolhouse, Mark E.J.Thumbi, S.M.Jennings, A.Chase-Topping, M.Callaby, R.Kiara, Henry K.Oosthuizen, M.C.Mbole-Kariuki, Mary N.Conradie, I.Handel, I.G.Poole, Elizabeth J.Njiiri, E.Collins, N.E.Murray, G.Tapio, M.Auguet, O.T.Weir, W.Morrison, W. IvanKruuk, L.E.B.Bronsvoort, B.M. de C.Hanotte, Olivier H.Coetzer, K.Toye, Philip G.[Co-infections determine patterns of mortality in a population exposed to parasite infection]Co-infections determine patterns of mortality in a population exposed to parasite infection

Butana and Kenana are two types of zebu cattle found in Sudan. They are unique amongst African indigenous zebu cattle because of their high milk production. Aiming to understand their genome structure, we genotyped 25 individuals from each breed using the Illumina BovineHD Genotyping BeadChip. Ge...


Bahbahani, HussainSalim, B.Almathen, F.Al Enezi, F.Mwacharo, Joram M.Hanotte, Olivier H.[Signatures of positive selection in African Butana and Kenana dairy zebu cattle]Signatures of positive selection in African Butana and Kenana dairy zebu cattle

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