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Isometamidium chloride is the most important chemoprophylactic agent used in the control of African bovine trypanosomiasis, although breakdowns in prophylaxis have been observed in the field. It is not usually apparent whether these breakdowns are due to inadequate drug dosage regimens, or to the...


Eisler, M.C.Maloo, S.H.Peregrine, A.S.Holmes, P.H.Thorpe, W.R.[Use of the isometamidium Elisa to measure serum concentrations of the drug in Jersey dairy cattle in Kenya]Use of the isometamidium Elisa to measure serum concentrations of the drug in Jersey dairy cattle in Kenya

Besides the in vitro test, two tests are very commonly used for the detection of trypanocidal drug resistance: the tests in mice and in ruminants. Since it has been shown that several parameters such as the number of trypanosomes inoculated and the time of treatment might influence the outcome of...


Geerts, S.Ndung'u, J.M.Murilla, G.Mbwambo, H.Sirryangwe, L.Machila, N.Delespaux, V.Brandt, J.Peregrine, A.S.McDermott, John J.Holmes, P.H.Eisler, M.C.[In vivo tests for the detection of resistance to trypanocidal drugs: Tests in mice and in ruminants]In vivo tests for the detection of resistance to trypanocidal drugs: Tests in mice and in ruminants

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