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Trypanosoma brucei contain a serine oligopeptidase (OP-Tb) that is released into (and remains active in) the blood of trypanosome-infected animals. Here a similar enzyme from Trypanosoma congolense is described. This oligopeptidase, called OP-Tc, was purified using three-phase partitioning, and i...


Morty, R.E.Authié, E.Troeberg, L.Lonsdale-Eccles, J.D.Coetzer, T.H.T.[Purification and characterisation of a typsin-like serine oligo peptidase from Trypanosoma congolense]Purification and characterisation of a typsin-like serine oligo peptidase from Trypanosoma congolense
Fish, W.R.Zeres, M.Nkhungulu, M.Muriuki, C.W.Ndegwa, D.M.Lonsdale-Eccles, J.D.Steyaert, J.[Primary structure and partial characterization of a life-cycles-regulated cysteine protease from Trypanosoma (Nannomonas) congolense]Primary structure and partial characterization of a life-cycles-regulated cysteine protease from Trypanosoma (Nannomonas) congolense
Mbawa, Z.R.Webster, P.Lonsdale-Eccles, J.D.[Immulocalization of a cysteine protease within the lysosomal system of Trypanosoma congolense]Immulocalization of a cysteine protease within the lysosomal system of Trypanosoma congolense
Fish, W.R.Muriuki, C.W.Muthiani, A.M.Grab, D.J.Lonsdale-Eccles, J.D.[Disulfide bond involvement in the maintenance of the cryptic nature of the cross-reacting determinant of metacyclic forms of Trypanosoma congolense]Disulfide bond involvement in the maintenance of the cryptic nature of the cross-reacting determinant of metacyclic forms of Trypanosoma congolense
Lonsdale-Eccles, J.D.Mpimbaza, G.W.N.Mbawa, Z.M.Kornblatt, J.[Characterisation of the proteases of Trypanosoma congolense and Trypanosoma brucei]Characterisation of the proteases of Trypanosoma congolense and Trypanosoma brucei

African trypanosomes contain cysteine proteases (ttypanopains) the activity of which can be measured by in vitro digestion of fibrinogen, after electophoresis in fibrinogen-containing SDS/polyacrylamide gels. When assessed by this procedure, trypanopain from Trypanosoma brucei (trypanopain-Tb) is...


Lonsdale-Eccles, J.D.Mpimbaza, G.W.N.Nkhungulu, Z.R.M.Olobo, J.Grab, D.J.[Trypanosomatid cysteine protease activity may be enhanced by a kininogen-like moiety from host serum]Trypanosomatid cysteine protease activity may be enhanced by a kininogen-like moiety from host serum
Sutherland, I.A.Peregrine, A.S.Lonsdale-Eccles, J.D.Holmes, P.H.[Reduced accumulation of isometamidum by drug resistant Trypanosoma congolense]Reduced accumulation of isometamidum by drug resistant Trypanosoma congolense

Fish, W.R.Grab, D.J.Lonsdale-Eccles, J.D.[The cross-reacting determinant of the variable surface glycoprotein of metacyclic Trypanosoma congolense]The cross-reacting determinant of the variable surface glycoprotein of metacyclic Trypanosoma congolense

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