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A study was carried out to determine whether a drug-resistant trypanosome population could influence the survival of a drug-sensitive population in mixed infections in goats. To identify both populations during the course of a mixed infection, a system for distinguishing them was developed; using...


Burudi, E.M.E.Peregrine, A.S.Majiwa, P.A.O.Mbiuki, S.M.Murphy, N.B.[Response of diminazene-resistance and diminazene-susceptible Trypanosoma congolense to treatment with diminazene when occuring as a mixed infection in goats]Response of diminazene-resistance and diminazene-susceptible Trypanosoma congolense to treatment with diminazene when occuring as a mixed infection in goats
Majiwa, P.A.O.Masake, R.A.Nantulya, V.M.Hamers, R.Matthyssens, G.[Trypanosoma (Nannomonas) congolense. Identification of two karyotypic groups]Trypanosoma (Nannomonas) congolense. Identification of two karyotypic groups

Ten trypanosome isolates were collected at random from cattle at Ghibe, Ethiopia, in February 1993 and all shown to be savannah-type Trypanosoma congolense. When inoculated into naive Boran (Bos indicus) calves, all 10 isolates were resistant to diminazene aceturate (Berenil), isometamidium chlor...


Mulugeta, W.Wilkes, J.Mulatu, W.Majiwa, P.A.O.Masake, R.Peregrine, A.S.[Long-term occurrence of Trypanosoma congolense resistant to diminazene, isometamidium and homidium in cattle at Ghibe, Ethiopia]Long-term occurrence of Trypanosoma congolense resistant to diminazene, isometamidium and homidium in cattle at Ghibe, Ethiopia
Majiwa, P.A.O.Maina, M.Waitumbi, J.N.Mihok, S.Zweygarth, E.[Trypanosoma (Nannomonas) congolense. Molecular characterization of a new genotype from Tsavo, Kenya]Trypanosoma (Nannomonas) congolense. Molecular characterization of a new genotype from Tsavo, Kenya
Majiwa, P.A.O.Webster, P.[A repetitive deoxyribonucleic acid sequence that distinguishes Trypanosoma simiae from T. congolense]A repetitive deoxyribonucleic acid sequence that distinguishes Trypanosoma simiae from T. congolense

Transcripts which encode two metacyclic-form-specific variable surface glycoproteins (mVSGs) of Trypanosoma congolense IL3000 have been cloned into baculovirus expression vectors using a novel transfer vector, pAcL11. One of the recombinant baculoviruses (AcVSG1) expressed a mVSG as a glycoprotei...


Urakawa, T.Eshita, Y.Fukuma, T.Hirumi, H.Hirumi, K.Majiwa, P.A.O.[Expression of Trypanosoma congolense antigens in spodoptera frugiperdia insect cells]Expression of Trypanosoma congolense antigens in spodoptera frugiperdia insect cells

The recent genome initiatives of the neglected parasites Trypanosoma vivax and Trypanosoma congolense, and the vector tsetse are promising with regards to the data available in public databases. While these genome initiatives and the potential for developing new drugs and vaccines are admirable, ...


Davila, A.M.R.Majiwa, P.A.O.Grisard, E.C.Aksoy, S.Hide, W.[Response to Hertz-Fowler and Berriman: Continuing tsetse and trypanosoma genome sequencing projects]Response to Hertz-Fowler and Berriman: Continuing tsetse and trypanosoma genome sequencing projects

Acute Trypanosoma congolense infection induced moderate, transient anemia in N'Dama cattle (trypanotolerant) and severe anemia in Boran cattle (trypanosusceptible). Erythropoietin receptor (EpoR) was cloned and sequenced from the two breeds of cattle. A single position mutation of Tyr in the Bora...


Suliman, H.B.Logan-Henfrey, L.L.Majiwa, P.A.O.Ole-MoiYoi, O.K.Feldman, B.F.[Analysis of erythropoietin and erythropoietin receptor genes expression in cattle during acute infection with Trypanosoma congolense]Analysis of erythropoietin and erythropoietin receptor genes expression in cattle during acute infection with Trypanosoma congolense

The complete nucleotide sequences were determined for three transcripts each encoding a different variant surface glycoprotein (VSG) of Trypanosoma (Nannomonas) congolense. The nucleotide sequence was determined also for a transcript encoding a fourth VSG, but this was truncated. The data obtaine...


Urakawa, T.Eshita, Y.Majiwa, P.A.O.[The primary structure of Trypanosoma (Nannomonas) congolense variant surface glycoproteins]The primary structure of Trypanosoma (Nannomonas) congolense variant surface glycoproteins
Majiwa, P.A.O.Hamers, R.Meirvenne, N. vanMatthyssens, G.[Evidence for genetic diversity in Trypanosoma (Nannomonas) congolense]Evidence for genetic diversity in Trypanosoma (Nannomonas) congolense

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