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Resistance to the drugs used to control African animal trypanosomosis is increasingly recognised as a constraint to livestock production in sub-Saharan Africa. The most commonly used tests for detection of trypanocidal drug resistance are tests using mice or ruminants, but these suffer from lack ...


Eisler, M.C.Brandt, J.Bauer, B.Clausen, P.H.Delespaux, V.Holmes, P.H.Ilemobade, A.Machila, N.Mbwambo, H.McDermott, John J.Mehlitz, D.Murilla, G.Ndung'u, J.M.Peregrine, A.S.Sidibe, I.Sinyangwe, L.Geerts, S.[Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle]Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle

Smallholder livestock keepers represent almost 20% of the world population and steward most of the agricultural land in the tropics. Observed and expected increases in future demand for livestock products in developing countries provide unique opportunities for improving livelihoods and linked to...


McDermott, John J.Staal, Steven J.Freeman, H.A.Herrero, Mario T.Steeg, Jeannette van de[Sustaining intensification of smallholder livestock systems in the tropics]Sustaining intensification of smallholder livestock systems in the tropics
O'Callaghan, C.J.McDermott, John J.Katende, J.M.Adams, J.E.Perry, Brian D.Young, A.S.[Analysis of longitudinal serological data for Theileria parva]Analysis of longitudinal serological data for Theileria parva

East Coast fever (ECF), caused by Theileria parva, is the most important tick-borne disease of cattle in much of eastern, central and southern Africa. In Kenya, immunization against ECF has been performed in many field trials using the infection and treatment method. The main targets for immuniza...


Deem, S.L.Perry, Brian D.Katende, J.M.McDermott, John J.Mahan, S.M.Maloo, S.H.Morzaria, S.P.Musoke, A.J.Rowlands, G.J.[Variations in prevalence rates of tick-borne diseases in Zebu cattle by agroecological zone: Implications for East Coast fever immunization]Variations in prevalence rates of tick-borne diseases in Zebu cattle by agroecological zone: Implications for East Coast fever immunization

The most important tick-borne disease of cattle in eastern, central and southern Africa is East Coast fever (ECF) caused by Theileria parva and transmitted by the tick Rhipicephalus appendiculatus. Other less-important tick-borne diseases in cattle are benign theileriosis caused by Theileria muta...


Gitau, G.K.Perry, Brian D.Katende, J.M.McDermott, John J.Morzaria, S.P.Young, A.S.[The prevalence of serum antibodies to tick-borne infections in cattle in smallholder dairy farms in Murang'a District, Kenya; a cross-sectional study]The prevalence of serum antibodies to tick-borne infections in cattle in smallholder dairy farms in Murang'a District, Kenya; a cross-sectional study

Bovine mastitis and mastitis control were investigated on smallholder farms in central Kenya. After an initial observational study, a clinical trial to assess the impact of three different mastitis control strategies - (1) improved udder hygiene (2) treatment of subclinical cases, and (3) a combi...


Omore, Amos O.McDermott, John J.Arimi, S.M.Kyule, M.N.[Impact of mastitis control measures on milk production and mastitis indicators in smallholder dairy farms in Kiambu District, Kenya]Impact of mastitis control measures on milk production and mastitis indicators in smallholder dairy farms in Kiambu District, Kenya

The aim of this study was to assess, whether polymerase chain reaction (PCR) allows sensitive screening of treatment failure suspicions in areas, where drug resistance against African animal trypanosomosis (AAT) appears to be a problem. PCR was used to detect trypanosome infections prior to, 14 ...


Gall, Y.Woitag, T.Bauer, B.Sidibe, I.McDermott, John J.Mehlitz, D.Clausen, P.H.[Trypanocidal failure suggested by PCR results in cattle field samples]Trypanocidal failure suggested by PCR results in cattle field samples

Drug resistant trypanosome infections in livestock have been Reported from 13 sub-Saharan countries so far, in eight of which multiple resistance occurs. Since new trypanocides are unlikely to appear on the market in the near future, information about the occurrence, extent and impact of drug res...


Gall, Y.Woitag, J.Bauer, B.Sidibe, I.McDermott, John J.Eisler, M.C.Mehlitz, D.Clausen, P.H.[Detection of trypanocide failure in cattle: Diagnostic potential of PCR compared to parasitological methods]Detection of trypanocide failure in cattle: Diagnostic potential of PCR compared to parasitological methods

Currently in Southeast Uganda, FITCA (EU funded Farming in Tsetse Controlled Areas Project) is involved in an intervention programme against both animal trypanosomiasis and human sleeping sickness. This is a regional project involving Kenya, Ethiopia, Tanzania and Uganda. In southeast Uganda, the...


Fyfe. K.Picozzi, K.Fèvre, Eric M.Wasiwa, C.McDermott, John J.Welburn, S.C.[Assessment of trypanosome prevalence in FITCA high risk areas]Assessment of trypanosome prevalence in FITCA high risk areas
Grace, DeliaJones, B.McKeever, Declan J.Pfeiffer, Dirk U.Mutua, F.Njuki, JemimahMcDermott, John J.Rushton, JonathanSaid, Mohammed YahyaKock, R.Alonso, Silvia[A systematic review of zoonoses at the interface of livestock and wildlife]A systematic review of zoonoses at the interface of livestock and wildlife

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