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Conference Proceedings 1995

Autor: McKeever, Declan J.

The main aim of this meeting was to review those developments in the fields of immunology and immunoparasitology that have relevance to the development of vaccination strategies for ECF and trypanosomiasis. Of relevance to the control of ECF were recent developments in the elucidation of events t...

Enlace original: https://cgspace.cgiar.org/handle/10568/2726

Investigación en Agricultura
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McKeever, Declan J. ,  [Novel immunization strategies against protozoan parasites. Proceedings of a workshop] ,  Novel immunization strategies against protozoan parasites. Proceedings of a workshop
Journal Article 1998

Autor: McKeever, Declan J. Morrison, W. Ivan

A first-gneration subunit vaccine for East Coast fever based on the Theileria parva p67 sporozoite surface antigen is entering preliminary field trials. Intensive efforts are also focused on the identification of a schizont-specific omponen for incorporation in a second-generation multi-component...

Enlace original: https://cgspace.cgiar.org/handle/10568/32963

Investigación en Agricultura
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McKeever, Declan J. ,  Morrison, W. Ivan ,  [Invited review Novel vaccines against Theileria parva: prospects for sustainability] ,  Invited review Novel vaccines against Theileria parva: prospects for sustainability
Journal Article 1995

Autor: Nene, Vishvanath Inumaru, S. McKeever, Declan J. Morzaria, S.P. Shaw, M. Musoke, A.J.

Previous data showed that six out of a group of nine cattle inoculated with NS1-p67, a recombinant form of a 67-KDa Theileria parva sporozoite surface protein, were immune to East Coast fever. This bacterialy expressed antigen encoded all 709 amino acid residues of p67 fused to the C-terminal end...

Enlace original: https://cgspace.cgiar.org/handle/10568/28744

Investigación en Agricultura
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Nene, Vishvanath ,  Inumaru, S. ,  McKeever, Declan J. ,  Morzaria, S.P. ,  Shaw, M. ,  Musoke, A.J. ,  [Characterization of an insect cell-derived Theileria parva sporozoite vaccine antigen and immunogenicity in cattle] ,  Characterization of an insect cell-derived Theileria parva sporozoite vaccine antigen and immunogenicity in cattle
Journal Article 2004

Autor: Ballingall, K.T. Luyai, A. Rowlands, G.J. Sales, J. Musoke, A.J. Morzaria, S.P. McKeever, Declan J.

Initial laboratory trials of an experimental subunit vaccine against Theileria parva based on the 67-kDa major sporozoite surface antigen revealed a range of responses to challenge. We have analyzed convergence in seven sets of monozygotic twins which suggests that genetic factors may have an i...

Enlace original: https://cgspace.cgiar.org/handle/10568/28758

Investigación en Agricultura
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Ballingall, K.T. ,  Luyai, A. ,  Rowlands, G.J. ,  Sales, J. ,  Musoke, A.J. ,  Morzaria, S.P. ,  McKeever, Declan J. ,  [Bovine leukocyte antigen major histocompatibility complex class II DRB3*2703 and DRB3*1501 alleles are associated with variation in levels of protection against Theileria parva challenge following immunization with the sporozoite p67 antigen] ,  Bovine leukocyte antigen major histocompatibility complex class II DRB3*2703 and DRB3*1501 alleles are associated with variation in levels of protection against Theileria parva challenge following immunization with the sporozoite p67 antigen
Journal Article 1998

Autor: Mwangi, D.M. Mahan, S.M. Nyanjui, J.K. Taracha, E.L.N. McKeever, Declan J.

Peripheral blood mononuclear cells (PBMC) from immune cattle proliferate in the presence of autologous Cowdria ruminantium-infected endothelial cells and monocytes. Endothelial cells required treatment with T-cell growth factors to induce class II major histocompatibility complex expression prior...

Enlace original: https://cgspace.cgiar.org/handle/10568/28756

Investigación en Agricultura
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Mwangi, D.M. ,  Mahan, S.M. ,  Nyanjui, J.K. ,  Taracha, E.L.N. ,  McKeever, Declan J. ,  [Immunization of cattle by infection with Cowdria ruminantium elicits T lymphocytes that recognize autologous, infected endothelial cells and monocytes] ,  Immunization of cattle by infection with Cowdria ruminantium elicits T lymphocytes that recognize autologous, infected endothelial cells and monocytes
Journal Article 1997

Autor: Totte, P. McKeever, Declan J. Martínez, D. Bensaid, A.

Cattle were successfully immunized against heartwater with a lysate of Cowdria ruminantium formulated in Freund's adjuvant. Vaccinated animals proved fully resistant to virulent challenge 3 and 10 months after vaccination. For the first time a helper T lymphocyte response to Cowdria antigens was ...

Enlace original: https://cgspace.cgiar.org/handle/10568/28765

Investigación en Agricultura
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Totte, P. ,  McKeever, Declan J. ,  Martínez, D. ,  Bensaid, A. ,  [Analysis of T-cell responses in cattle immunized against heartwater by vaccination with killed elementary bodies of Cowdria ruminantium] ,  Analysis of T-cell responses in cattle immunized against heartwater by vaccination with killed elementary bodies of Cowdria ruminantium
Book Chapter 1994

Autor: Musoke, A.J. McKeever, Declan J. Morzaria, S.P. Nkonge, C. Nene, Vishvanath

The Development of a recombinant Theileria parva vaccine is discussed under the following headings: mechanisms of protection against ECF [East Coast fever]; cloning and expression of p67; immunization and challenge of cattle; interpretation of immunization and challenge data.

Enlace original: https://cgspace.cgiar.org/handle/10568/50104

Investigación en Agricultura
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Musoke, A.J. ,  McKeever, Declan J. ,  Morzaria, S.P. ,  Nkonge, C. ,  Nene, Vishvanath ,  [A recombinant vaccine for Theileria parva] ,  A recombinant vaccine for Theileria parva
Conference Paper 1995

Autor: Musoke, A.J. McKeever, Declan J. Morzaria, S.P. Nkonge, C. Nene, Vishvanath

Theileria parva, a protozoan parasite of cattle, causes a disease called East Coast fever. The disease is of economic importance because it causes high morbidity and mortality and limits the development of the cattle industry. This paper highlights the experiences with immunization against Theile...

Enlace original: https://cgspace.cgiar.org/handle/10568/2830

Investigación en Agricultura
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Musoke, A.J. ,  McKeever, Declan J. ,  Morzaria, S.P. ,  Nkonge, C. ,  Nene, Vishvanath ,  [Experiences with immunization against Theileria parva using p67, a sporozoite surface antigen] ,  Experiences with immunization against Theileria parva using p67, a sporozoite surface antigen

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