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Journal Article 2011-09-29

Autor: Nkando, I. Ndinda, J. Kuria, J. Naessens, Jan Mbithi, F. Schnier, C. Gicheru, M. McKeever, Declan J. Wesonga, H.O.

A live, attenuated vaccine is currently the only viable option to control of CBPP in Africa. It has been suggested that simple modifications to current vaccines and protocols might improve efficacy in the field. In this report we compared the current vaccine formulation with a buffered preparatio...

Enlace original: https://cgspace.cgiar.org/handle/10568/16450

Investigación en Agricultura
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Nkando, I. ,  Ndinda, J. ,  Kuria, J. ,  Naessens, Jan ,  Mbithi, F. ,  Schnier, C. ,  Gicheru, M. ,  McKeever, Declan J. ,  Wesonga, H.O. ,  [Efficacy of two vaccine formulations against contagious bovine pleuropneumonia (CBPP) in Kenyan indigenous cattle] ,  Efficacy of two vaccine formulations against contagious bovine pleuropneumonia (CBPP) in Kenyan indigenous cattle
Journal Article 1999

Autor: McKeever, Declan J. Taracha, E.L.N. Morrison, W. Ivan Musoke, A.J. Morzaria, S.P.

Theileria parva is an intracellular sporozoan parasite that infects and transforms bovine lymphocytes, causing a severe lymphoproliferative disease known as East Coast fever in eastern, central and southern Africa. In this article, Declan McKeever and colleagues summarize the current understandin...

Enlace original: https://cgspace.cgiar.org/handle/10568/33104

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McKeever, Declan J. ,  Taracha, E.L.N. ,  Morrison, W. Ivan ,  Musoke, A.J. ,  Morzaria, S.P. ,  [Protective immune mechanisms against Theileria parva: Evolution of vaccine development strategies] ,  Protective immune mechanisms against Theileria parva: Evolution of vaccine development strategies
Journal Article 1998

Autor: McKeever, Declan J. Morrison, W. Ivan

A first-gneration subunit vaccine for East Coast fever based on the Theileria parva p67 sporozoite surface antigen is entering preliminary field trials. Intensive efforts are also focused on the identification of a schizont-specific omponen for incorporation in a second-generation multi-component...

Enlace original: https://cgspace.cgiar.org/handle/10568/32963

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McKeever, Declan J. ,  Morrison, W. Ivan ,  [Invited review Novel vaccines against Theileria parva: prospects for sustainability] ,  Invited review Novel vaccines against Theileria parva: prospects for sustainability
Journal Article 1995

Autor: Nene, Vishvanath Inumaru, S. McKeever, Declan J. Morzaria, S.P. Shaw, M. Musoke, A.J.

Previous data showed that six out of a group of nine cattle inoculated with NS1-p67, a recombinant form of a 67-KDa Theileria parva sporozoite surface protein, were immune to East Coast fever. This bacterialy expressed antigen encoded all 709 amino acid residues of p67 fused to the C-terminal end...

Enlace original: https://cgspace.cgiar.org/handle/10568/28744

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Nene, Vishvanath ,  Inumaru, S. ,  McKeever, Declan J. ,  Morzaria, S.P. ,  Shaw, M. ,  Musoke, A.J. ,  [Characterization of an insect cell-derived Theileria parva sporozoite vaccine antigen and immunogenicity in cattle] ,  Characterization of an insect cell-derived Theileria parva sporozoite vaccine antigen and immunogenicity in cattle
Journal Article 1999

Autor: McKeever, Declan J. Rege, J.E.O.

Development of improved vaccine and diagnostic-based disease control strategies has benefited considerably from advances in biotechnology, particularly those relating to recombinant DNA technology. Efficiency of the vaccine development process has been increased at all levels, from the analysis o...

Enlace original: https://cgspace.cgiar.org/handle/10568/29189

Investigación en Agricultura
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McKeever, Declan J. ,  Rege, J.E.O. ,  [Vaccines and diagnostic tools for animal health: The influence of biotechnology] ,  Vaccines and diagnostic tools for animal health: The influence of biotechnology
Journal Article 1995

Autor: Morrison, W. Ivan Taracha, E.L.N. McKeever, Declan J.

Studies of the immune responses of cattle to Theileria parva have provided evidence that immunity to the parasite can operate at two levels, namely the sporozoite and the schizont-infected lymphoblast. Antibodies that neutralize the infectivity of sporozoites have been detected in the serum of hy...

Enlace original: https://cgspace.cgiar.org/handle/10568/29881

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Morrison, W. Ivan ,  Taracha, E.L.N. ,  McKeever, Declan J. ,  [Theileriosis: Progress towards vaccine development through understanding immune responses to the parasite] ,  Theileriosis: Progress towards vaccine development through understanding immune responses to the parasite
Book Chapter 1994

Autor: Musoke, A.J. McKeever, Declan J. Morzaria, S.P. Nkonge, C. Nene, Vishvanath

The Development of a recombinant Theileria parva vaccine is discussed under the following headings: mechanisms of protection against ECF [East Coast fever]; cloning and expression of p67; immunization and challenge of cattle; interpretation of immunization and challenge data.

Enlace original: https://cgspace.cgiar.org/handle/10568/50104

Investigación en Agricultura
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Musoke, A.J. ,  McKeever, Declan J. ,  Morzaria, S.P. ,  Nkonge, C. ,  Nene, Vishvanath ,  [A recombinant vaccine for Theileria parva] ,  A recombinant vaccine for Theileria parva
Book Chapter 1995

Autor: Musoke, A.J. Nene, Vishvanath McKeever, Declan J.
Enlace original: https://cgspace.cgiar.org/handle/10568/50479

Investigación en Agricultura
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Musoke, A.J. ,  Nene, Vishvanath ,  McKeever, Declan J. ,  [Epitope specificity of bovine immune responses to the major surface antigen of Theileria parva sporozoites] ,  Epitope specificity of bovine immune responses to the major surface antigen of Theileria parva sporozoites
Conference Paper 1995

Autor: Musoke, A.J. McKeever, Declan J. Morzaria, S.P. Nkonge, C. Nene, Vishvanath

Theileria parva, a protozoan parasite of cattle, causes a disease called East Coast fever. The disease is of economic importance because it causes high morbidity and mortality and limits the development of the cattle industry. This paper highlights the experiences with immunization against Theile...

Enlace original: https://cgspace.cgiar.org/handle/10568/2830

Investigación en Agricultura
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Musoke, A.J. ,  McKeever, Declan J. ,  Morzaria, S.P. ,  Nkonge, C. ,  Nene, Vishvanath ,  [Experiences with immunization against Theileria parva using p67, a sporozoite surface antigen] ,  Experiences with immunization against Theileria parva using p67, a sporozoite surface antigen

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