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The indirect MAP 1B ELISA based on the recombinant MAP 1B fragment of the immunodominant MAP 1 protein of Ehrlichia ruminantium is considered to be the most sensitive and specific assay for the serodiagnosis of heartwater. In this study, we evaluated its reliability in detecting exposure to E....


Peter, T.F.O'Callaghan, C.J.Medley, G.F.Perry, Brian D.Semu, S.M.Mahan, S.M.[Population-based evaluation of the Ehrlichia ruminantium MAP 1B indirect ELISA]Population-based evaluation of the Ehrlichia ruminantium MAP 1B indirect ELISA

The high prevalence of resistance of Haemonchus contortus to all major anthelmintic groups has prompted investigations into alternative control methods in South Africa, including the use of copper oxide wire particle (COWP) boluses. To assess the efficacy of COWP against H. contortus in indigenou...


Vatta, A.F.Waller, P.J.Githiori, J.B.Medley, G.F.[The potential to control Haemonchus contortus in indigenous South African goats with copper oxide wire particles]The potential to control Haemonchus contortus in indigenous South African goats with copper oxide wire particles
Young, A.S.Ochanda, H.Perry, Brian D.Morzaria, S.P.Dolan, T.T.Medley, G.F.Gettinby, G.[The biology of the transmission dynamics of Theileria parva]The biology of the transmission dynamics of Theileria parva
O'Callaghan, C.J.Medley, G.F.Kiara, Henry K.McDermott, John J.Musoke, A.J.Morzaria, S.P.Perry, Brian D.[Quantitative analysis of dose-response effects in the transmission dynamics of Theileria parva and the impact of sporozoite-neutralising vaccines]Quantitative analysis of dose-response effects in the transmission dynamics of Theileria parva and the impact of sporozoite-neutralising vaccines

A mathematical description of the transmission dynamics of the tick-borne infection Cowdria ruminantium in commercial beef enterprises in Zimbabwe was used to consider the potential impact of a candidate vaccine to prevent heartwater. The important characteristics of the vaccine were (1) a delay ...


O'Callaghan, C.J.Medley, G.F.Peter, T.F.Mahan, S.M.Perry, Brian D.[Predicting the effect of vaccination on the transmission dynamics of heartwater (Cowdria ruminantium infection)]Predicting the effect of vaccination on the transmission dynamics of heartwater (Cowdria ruminantium infection)

As part of a series of studies associated with the development of improved vaccines for heartwater (a tick-borne disease of ruminant livestock caused by Cowdria ruminantium), field surveys were carried out to assess losses associated with the disease and the costs associated with controlling it i...


Chamboko, TafireyiMukhebi, A.W.Callaghan, C.J.O.Peter, T.F.Kruska, R.L.Medley, G.F.Mahan, S.M.Perry, Brian D.[The control of heartwater on large-scale commercial and smallholder farms in Zimbabwe]The control of heartwater on large-scale commercial and smallholder farms in Zimbabwe

Heartwater, caused by the rickettsial organism Cowdria ruminantium, is a serious constraint to livestock development in much of sub-Saharan Africa. Traditionally, the disease has been controlled by the use of chemical acaricides to control the vector tick. The University of Florida/USAID-supporte...


Mukhebi, A.W.Chamboko, TafireyiO'Callaghan, C.J.Peter, T.F.Kruska, R.L.Medley, G.F.Mahan, S.M.Perry, Brian D.[An assessment of the economic impact of heartwater (Cowdria ruminantium infection) and its control in Zimbabwe]An assessment of the economic impact of heartwater (Cowdria ruminantium infection) and its control in Zimbabwe

Adult Amblyomma hebraeum ticks, the principle vector of heartwater (cowdriosis) of domestic ruminants in southern Africa, were collected in pheromone traps placed in Kruger National Park, an exclusively wildlife sanctuary in South Africa. These ticks transmitted Cowdria ruminantium, the rickettsi...


Peter, T.F.Bryson, N.R.Perry, Brian D.O'Callaghan, C.J.Medley, G.F.Smith, G.E.Mlambo, G.Horak, I.G.Burridge, M.J.Mahan, S.M.[Cowdria ruminantium infection in ticks in the Kruger National Park]Cowdria ruminantium infection in ticks in the Kruger National Park

The authors highlight the reliance on repeated natural infections by tickborne pathogens to maintain immunity in immunized herds. That incidence of clinical heartwater in cattle, caused by Cowdria ruminantium, is low while intensive acaricide use interrupts transmission of pathogens. Evidence is ...


Perry, Brian D.Chamboko, TafireyiMahan, S.M.Medley, G.F.Minjauw, B.O'Callaghan, C.J.Peter, T.F.[The economics of integrated tick and tick-borne disease control on commercial farms in Zimbabwe]The economics of integrated tick and tick-borne disease control on commercial farms in Zimbabwe

The transmission of Theileria parva by nymphal and adult Rhipicephalus appendiculatus was compared by the assessment of salivary gland infections in tick batches fed on the same group of infected cattle at the same time. When larval and nymphal R. appendiculatus Muguga ticks were fed concurrently...


Ochanda, H.Young, A.S.Wells, C.Medley, G.F.Perry, Brian D.[Comparison of the transmission of Theileria parva between different instars of Rhipicephalus appendiculatus]Comparison of the transmission of Theileria parva between different instars of Rhipicephalus appendiculatus

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