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Theileria parva causes an acute lympho-proliferative disease in cattle, which can result in death of susceptible animals within 2-3 weeks of infection. Analyses of the cellular response in the lymph node draining the site of infection demonstrated an early T cell response, with the appearance of ...


Houston, E.F.Taracha, E.L.N.Brackenbury, L.MacHugh, Niall D.McKeever, Declan J.Charleston, B.Morrison, W. Ivan[Infection of cattle with Theileria parva induces an early CD8 T cell response lacking appropriate effector function]Infection of cattle with Theileria parva induces an early CD8 T cell response lacking appropriate effector function
Morrison, W. IvanGoddeeris, M.Brown, W.C.Baldwin, C.L.Teale, A.J.[Theileria parva in cattle: Characterization of infected lymphocytes and the immune responses they provoke]Theileria parva in cattle: Characterization of infected lymphocytes and the immune responses they provoke

The importance of T-cell-mediate immune responses in the control of intracellular protozoan parasites is now well established 1-3. The killing of parasitized cells by T cells and cytokine-mediated effects on growth and viability of the intracellular parasites have both been implicated as effector...


Morrison, W. IvanTaracha, E.L.N.McKeever, Declan J.[Contribution of T-cell responses to immunity and pathogenesis in infection with Theileria parva]Contribution of T-cell responses to immunity and pathogenesis in infection with Theileria parva
Morrison, W. IvanRoelants, G.E.Mayor-Withey, K.S.Murray, M.[Susceptibility of inbred strains of mice to Trypanosoma congolense. Correlation with changes in spleen lymphocyte populations]Susceptibility of inbred strains of mice to Trypanosoma congolense. Correlation with changes in spleen lymphocyte populations
Teale, A.J.Morrison, W. IvanGoddeeris, B.M.Groocock, C.M.Stagg, D.A.Spooner, R.L.[Bovine alloreactive cytotoxic cells generated in vitro. Target specificity in relation to BoLA phenotype]Bovine alloreactive cytotoxic cells generated in vitro. Target specificity in relation to BoLA phenotype
Ellis, J.A.Baldwin, C.L.MacHugh, Niall D.Bensaid, A.M.Teale, A.J.Goddeeris, B.M.Morrison, W. Ivan[Characterization by a monoclonal antibody and functional analysis of a subset of bovine T lymphocytes that express BoT8, a molecule analogous to human CD8]Characterization by a monoclonal antibody and functional analysis of a subset of bovine T lymphocytes that express BoT8, a molecule analogous to human CD8
McKeever, Declan J.MacHugh, Niall D.Goddeeris, B.M.Awino, EliasMorrison, W. Ivan[Bovine afferent lymph veiled cells differ from blood monocytes in phenotype and accessory function]Bovine afferent lymph veiled cells differ from blood monocytes in phenotype and accessory function
Teale, A.J.Baldwin, C.L.Morrison, W. IvanEllis, J.MacHugh, Niall D.[Phenotypic and functional characteristics of bovine T lymphocytes]Phenotypic and functional characteristics of bovine T lymphocytes

The target antigens recognized by bovine alloreactive cytotoxic T cells are discussed and compared with serologically defined bovine major histocompatibility complex (MHC) products which make up the bovine lymphocyte antigen (BoLA) system. The role of MHC products in T-cell function in other spe...


Teale, A.J.Morrison, W. IvanSpooner, R.L.Goddeeris, B.M.Groocock, C.M.Stagg, D.A.[Bovine alloreactive cytotoxic T cells]Bovine alloreactive cytotoxic T cells

The inductive requirements for proliferation of bovine peripheral blood mononuclear cells (PMB) in vitro, in the allogeneic mixed leucocyte reation (MLR), the autologous MLR and the autologous Theileria MLR were compared. In order to examine the role of monocytes in these reactions, methods were...


Goddeeris, B.M.Lalor, P.A.Morrison, W. Ivan[Bovine mixed leucocyte reactions and generation of cytotoxic cells]Bovine mixed leucocyte reactions and generation of cytotoxic cells

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