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Taracha, E.L.N.Goddeeris, M.Scott, J.R.Morrison, W. Ivan[Standardization of a technique for analysing the frequency of parasite-specific cytotoxic T lymphocyte precursors in cattle immunized with Theileria parva]Standardization of a technique for analysing the frequency of parasite-specific cytotoxic T lymphocyte precursors in cattle immunized with Theileria parva
Baldwin, C.L.Goddeeris, M.Morrison, W. Ivan[Bovine helper T-cell clones specific for lymphocytes infected with Theileria parva (Muguga)]Bovine helper T-cell clones specific for lymphocytes infected with Theileria parva (Muguga)
Goddeeris, B.M.Morrison, W. IvanTeale, A.J.[Generation of bovine cytotoxic cell lines, specific for cells infected with the protozoan parasite Theileria parva and restricted by products of the major histocompatibility complex]Generation of bovine cytotoxic cell lines, specific for cells infected with the protozoan parasite Theileria parva and restricted by products of the major histocompatibility complex

The relationship of strain specificity of class I major histocompatibility complex-restricted parasite-specific cytotoxic T lymphocytes (CTL) responses and cross-protection was investigated in an effort to verify the role of CTL in protection. The parasite strain specificity of the CTL responses ...


Taracha, E.L.N.Goddeeris, B.M.Morzaria, S.P.Morrison, W. Ivan[Parasite strain specificity of precursor cytotoxic T cells in individual animals correlates with cross-protection in cattle challenged with Theileria parva]Parasite strain specificity of precursor cytotoxic T cells in individual animals correlates with cross-protection in cattle challenged with Theileria parva

Theileria parva causes an acute lympho-proliferative disease in cattle, which can result in death of susceptible animals within 2-3 weeks of infection. Analyses of the cellular response in the lymph node draining the site of infection demonstrated an early T cell response, with the appearance of ...


Houston, E.F.Taracha, E.L.N.Brackenbury, L.MacHugh, Niall D.McKeever, Declan J.Charleston, B.Morrison, W. Ivan[Infection of cattle with Theileria parva induces an early CD8 T cell response lacking appropriate effector function]Infection of cattle with Theileria parva induces an early CD8 T cell response lacking appropriate effector function
Morrison, W. IvanGoddeeris, M.Brown, W.C.Baldwin, C.L.Teale, A.J.[Theileria parva in cattle: Characterization of infected lymphocytes and the immune responses they provoke]Theileria parva in cattle: Characterization of infected lymphocytes and the immune responses they provoke
Morrison, W. IvanBuscher, G.[The early events of infection with Theileria parva in cattle: Infectivity for cattle of leukocytes incubated in vitro with sporozoites]The early events of infection with Theileria parva in cattle: Infectivity for cattle of leukocytes incubated in vitro with sporozoites
Buscher, G.Morrison, W. IvanNelson, R.T.[Titration in cattle of infectivity and immunogenicity of autologous cell lines infected with Theileria parva]Titration in cattle of infectivity and immunogenicity of autologous cell lines infected with Theileria parva

The importance of T-cell-mediate immune responses in the control of intracellular protozoan parasites is now well established 1-3. The killing of parasitized cells by T cells and cytokine-mediated effects on growth and viability of the intracellular parasites have both been implicated as effector...


Morrison, W. IvanTaracha, E.L.N.McKeever, Declan J.[Contribution of T-cell responses to immunity and pathogenesis in infection with Theileria parva]Contribution of T-cell responses to immunity and pathogenesis in infection with Theileria parva

Studies of the immune responses of cattle to Theileria parva have provided evidence that immunity to the parasite can operate at two levels, namely the sporozoite and the schizont-infected lymphoblast. Antibodies that neutralize the infectivity of sporozoites have been detected in the serum of hy...


Morrison, W. IvanTaracha, E.L.N.McKeever, Declan J.[Theileriosis: Progress towards vaccine development through understanding immune responses to the parasite]Theileriosis: Progress towards vaccine development through understanding immune responses to the parasite

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