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Howard, C.J.Morrison, W. IvanBrown, W.C.Naessens, JanSopp, P.[Demonstration of two allelic forms of the bovine T cell antigen Bo5 (CD5) and studies of their inheritance]Demonstration of two allelic forms of the bovine T cell antigen Bo5 (CD5) and studies of their inheritance
Morrison, W. IvanGoddeeris, M.[The role of the MHC in immunity of cattle to the protozoan parasite Theileria parva]The role of the MHC in immunity of cattle to the protozoan parasite Theileria parva

Immunity against the bovine intracellular protozoan parasite Theileria parva has been shown to be mediated through the destruction of parasite infected lymphocytes by MHC class I restricted CD8+ CTL. Six parasite proteins targeted by CTL from T. parva immune cattle have been identified and raised...


Graham, S.P.Pelle, RogerVilliers, Etienne P. deYamage, M.Mwangi, D.M.Honda, Y.Ellis, S.A.MacHugh, Niall D.Morrison, W. IvanTaracha, E.L.N.[Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva]Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva
Masake, R.A.Morrison, W. Ivan[Evaluation of the structural and functional changes in the lymphoid organs of Boran cattle infected with Trypanosoma vivax]Evaluation of the structural and functional changes in the lymphoid organs of Boran cattle infected with Trypanosoma vivax
Goddeeris, B.M.Morrison, W. Ivan[Techniques for the generation, cloning and characterisation of bovine cytotoxic T cells specific for the protozoan Theileria parva]Techniques for the generation, cloning and characterisation of bovine cytotoxic T cells specific for the protozoan Theileria parva
Morrison, W. IvanMurray, M.Bovell, D.L.[The response of the murine lymphoid system to a chronic infection with Trypanosoma congolense. 1. The spleen]The response of the murine lymphoid system to a chronic infection with Trypanosoma congolense. 1. The spleen

Species: RuminantsTheileria parva is an intracellular protozoal parasite which causes East Coast Fever (ECF), a major constraint to cattle production in eastern and southern Africa. Characteristics of the protective CD8+ T-cell response against T. parva suggest it is focused on a limited number o...


Connelley, T.MacHugh, Niall D.Graham, S.Taracha, E.A.Burrells, A.Ngugi, D.Morrison, W. Ivan[The bovine CD8+ T-cell response to Theileria parva displays epitope immunodominance and oligoclonality]The bovine CD8+ T-cell response to Theileria parva displays epitope immunodominance and oligoclonality

Theileria parva is an intracellular sporozoan parasite that infects and transforms bovine lymphocytes, causing a severe lymphoproliferative disease known as East Coast fever in eastern, central and southern Africa. In this article, Declan McKeever and colleagues summarize the current understandin...


McKeever, Declan J.Taracha, E.L.N.Morrison, W. IvanMusoke, A.J.Morzaria, S.P.[Protective immune mechanisms against Theileria parva: Evolution of vaccine development strategies]Protective immune mechanisms against Theileria parva: Evolution of vaccine development strategies

A first-gneration subunit vaccine for East Coast fever based on the Theileria parva p67 sporozoite surface antigen is entering preliminary field trials. Intensive efforts are also focused on the identification of a schizont-specific omponen for incorporation in a second-generation multi-component...


McKeever, Declan J.Morrison, W. Ivan[Invited review Novel vaccines against Theileria parva: prospects for sustainability]Invited review Novel vaccines against Theileria parva: prospects for sustainability

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