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Journal Article 2019-05-01

Autor: Sitta, Tatjana Henson, Sonal P. Morrison, W. Ivan Toye, Philip G.
Enlace original: https://cgspace.cgiar.org/handle/10568/101122

Investigación en Agricultura
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Sitta, Tatjana ,  Henson, Sonal P. ,  Morrison, W. Ivan ,  Toye, Philip G. ,  [Similar levels of diversity in the gene encoding the p67 sporozoite surface protein of Theileria parva are observed in blood samples from buffalo and cattle naturally infected from buffalo] ,  Similar levels of diversity in the gene encoding the p67 sporozoite surface protein of Theileria parva are observed in blood samples from buffalo and cattle naturally infected from buffalo
Journal Article 2016-07-15

Autor: Hemmink, J.D. Weir, W. MacHugh, Niall D. Graham, S.P. Patel, Ekta Paxton, E. Shiels, B. Toye, Philip G. Morrison, W. Ivan Pelle, Roger

An infection and treatment protocol is used to vaccinate cattle against Theileria parva infection. Due to incomplete cross-protection between different parasite isolates, a mixture of three isolates, termed the Muguga cocktail, is used for vaccination. While vaccination of cattle in some regions ...

Enlace original: https://cgspace.cgiar.org/handle/10568/73303

Investigación en Agricultura
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Hemmink, J.D. ,  Weir, W. ,  MacHugh, Niall D. ,  Graham, S.P. ,  Patel, Ekta ,  Paxton, E. ,  Shiels, B. ,  Toye, Philip G. ,  Morrison, W. Ivan ,  Pelle, Roger ,  [Limited genetic and antigenic diversity within parasite isolates used in a live vaccine against Theileria parva] ,  Limited genetic and antigenic diversity within parasite isolates used in a live vaccine against Theileria parva
Journal Article 1979

Autor: Murray, M. Barry, J.D. Morrison, W. Ivan Williams, R.O. Hirumi, H. Rovis, L.A.

This review of the prospects for developing an immunization procedure against trypanosomiasis explores a number of promising avenues of research. Part I covers variable antigen types (VATs); metacyclic antigens; in vivo and in vitro attenuation; and molecular and genetic engineering. Part II, to ...

Enlace original: https://cgspace.cgiar.org/handle/10568/28622

Investigación en Agricultura
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Murray, M. ,  Barry, J.D. ,  Morrison, W. Ivan ,  Williams, R.O. ,  Hirumi, H. ,  Rovis, L.A. ,  [A review of the prospects for vaccination in African trypanosomiasis. Part I] ,  A review of the prospects for vaccination in African trypanosomiasis. Part I
Journal Article 1999

Autor: McKeever, Declan J. Taracha, E.L.N. Morrison, W. Ivan Musoke, A.J. Morzaria, S.P.

Theileria parva is an intracellular sporozoan parasite that infects and transforms bovine lymphocytes, causing a severe lymphoproliferative disease known as East Coast fever in eastern, central and southern Africa. In this article, Declan McKeever and colleagues summarize the current understandin...

Enlace original: https://cgspace.cgiar.org/handle/10568/33104

Investigación en Agricultura
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McKeever, Declan J. ,  Taracha, E.L.N. ,  Morrison, W. Ivan ,  Musoke, A.J. ,  Morzaria, S.P. ,  [Protective immune mechanisms against Theileria parva: Evolution of vaccine development strategies] ,  Protective immune mechanisms against Theileria parva: Evolution of vaccine development strategies
Journal Article 1998

Autor: McKeever, Declan J. Morrison, W. Ivan

A first-gneration subunit vaccine for East Coast fever based on the Theileria parva p67 sporozoite surface antigen is entering preliminary field trials. Intensive efforts are also focused on the identification of a schizont-specific omponen for incorporation in a second-generation multi-component...

Enlace original: https://cgspace.cgiar.org/handle/10568/32963

Investigación en Agricultura
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McKeever, Declan J. ,  Morrison, W. Ivan ,  [Invited review Novel vaccines against Theileria parva: prospects for sustainability] ,  Invited review Novel vaccines against Theileria parva: prospects for sustainability
Journal Article 1980

Autor: Murray, M. Barry, J.D. Morrison, W. Ivan Williams, R.O. Hirumi, H. Rovis, L.A.

In part I of this review of the prospects of vaccination against African trypanosomiasis, contained in the previous issue of World Animal Review, the constraints in developing a vaccine were discussed and current knowledge on the molecular biology of the trypanosome and on antigenic variation wit...

Enlace original: https://cgspace.cgiar.org/handle/10568/28623

Investigación en Agricultura
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Murray, M. ,  Barry, J.D. ,  Morrison, W. Ivan ,  Williams, R.O. ,  Hirumi, H. ,  Rovis, L.A. ,  [A review of the prospects for vaccination in African trypanosomiasis. Part II] ,  A review of the prospects for vaccination in African trypanosomiasis. Part II
Journal Article 1995

Autor: Morrison, W. Ivan Taracha, E.L.N. McKeever, Declan J.

Studies of the immune responses of cattle to Theileria parva have provided evidence that immunity to the parasite can operate at two levels, namely the sporozoite and the schizont-infected lymphoblast. Antibodies that neutralize the infectivity of sporozoites have been detected in the serum of hy...

Enlace original: https://cgspace.cgiar.org/handle/10568/29881

Investigación en Agricultura
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Morrison, W. Ivan ,  Taracha, E.L.N. ,  McKeever, Declan J. ,  [Theileriosis: Progress towards vaccine development through understanding immune responses to the parasite] ,  Theileriosis: Progress towards vaccine development through understanding immune responses to the parasite
Journal Article 2016-05-19

Autor: Fry, Lindsay M. Schneider, D.A. Frevert, C.W. Nelson, D.D. Morrison, W. Ivan Knowles, Donald P.

Respiratory failure and death in East Coast Fever (ECF), a clinical syndrome of African cattle caused by the apicomplexan parasite Theileria parva, has historically been attributed to pulmonary infiltration by infected lymphocytes. However, immunohistochemical staining of tissue from T. parva inf...

Enlace original: https://cgspace.cgiar.org/handle/10568/74287

Investigación en Agricultura
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Fry, Lindsay M. ,  Schneider, D.A. ,  Frevert, C.W. ,  Nelson, D.D. ,  Morrison, W. Ivan ,  Knowles, Donald P. ,  [East Coast fever caused by Theileria parva is characterized by macrophage activation associated with vasculitis and respiratory failure] ,  East Coast fever caused by Theileria parva is characterized by macrophage activation associated with vasculitis and respiratory failure
Journal Article 2018-09-15

Autor: Sitt, T. Pelle, Roger Chepkwony, M.C. Morrison, W. Ivan Toye, Philip G.
Enlace original: https://cgspace.cgiar.org/handle/10568/98857

Investigación en Agricultura
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Sitt, T. ,  Pelle, Roger ,  Chepkwony, M.C. ,  Morrison, W. Ivan ,  Toye, Philip G. ,  [Theileria parva antigens recognized by CD8+ T cells show varying degrees of diversity in buffalo-derived infected cell lines] ,  Theileria parva antigens recognized by CD8+ T cells show varying degrees of diversity in buffalo-derived infected cell lines
Journal Article 2018-03-15

Autor: Hemmink, J.D. Sitt, T. Pelle, Roger Klerk-Lorist, L.M. de Shiels, B. Toye, Philip G. Morrison, W. Ivan Weir, W.

An infection and treatment protocol involving infection with a mixture of three parasite isolates and simultaneous treatment with oxytetracycline is currently used to vaccinate cattle against Theileria parva. While vaccination results in high levels of protection in some regions, little or no pro...

Enlace original: https://cgspace.cgiar.org/handle/10568/90996

Investigación en Agricultura
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Hemmink, J.D. ,  Sitt, T. ,  Pelle, Roger ,  Klerk-Lorist, L.M. de ,  Shiels, B. ,  Toye, Philip G. ,  Morrison, W. Ivan ,  Weir, W. ,  [Ancient diversity and geographical sub-structuring in African buffalo Theileria parva populations revealed through metagenetic analysis of antigen-encoding loci] ,  Ancient diversity and geographical sub-structuring in African buffalo Theileria parva populations revealed through metagenetic analysis of antigen-encoding loci

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