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Previous data showed that six out of a group of nine cattle inoculated with NS1-p67, a recombinant form of a 67-KDa Theileria parva sporozoite surface protein, were immune to East Coast fever. This bacterialy expressed antigen encoded all 709 amino acid residues of p67 fused to the C-terminal end...


Nene, VishvanathInumaru, S.McKeever, Declan J.Morzaria, S.P.Shaw, M.Musoke, A.J.[Characterization of an insect cell-derived Theileria parva sporozoite vaccine antigen and immunogenicity in cattle]Characterization of an insect cell-derived Theileria parva sporozoite vaccine antigen and immunogenicity in cattle

Initial laboratory trials of an experimental subunit vaccine against Theileria parva based on the 67-kDa major sporozoite surface antigen revealed a range of responses to challenge. We have analyzed convergence in seven sets of monozygotic twins which suggests that genetic factors may have an i...


Ballingall, K.T.Luyai, A.Rowlands, G.J.Sales, J.Musoke, A.J.Morzaria, S.P.McKeever, Declan J.[Bovine leukocyte antigen major histocompatibility complex class II DRB3*2703 and DRB3*1501 alleles are associated with variation in levels of protection against Theileria parva challenge following immunization with the sporozoite p67 antigen]Bovine leukocyte antigen major histocompatibility complex class II DRB3*2703 and DRB3*1501 alleles are associated with variation in levels of protection against Theileria parva challenge following immunization with the sporozoite p67 antigen
Kibe, M.K.Ole-MoiYoi, O.K.Nene, VishvanathKhan, B.Allsopp, B.A.Collins, N.E.Morzaria, S.P.Gobright, E.I.Bishop, B.P.[Evidence for two single copy units in Theileria parva ribosomal RNA genes]Evidence for two single copy units in Theileria parva ribosomal RNA genes
Gerhards, J.Ebel, T.Dobbelaere, D.A.E.Morzaria, S.P.Musoke, A.J.Williams, R.O.Lipp, J.[Sequence and expression of a 90-kilodalton heat-shock protein family member of Theileria parva]Sequence and expression of a 90-kilodalton heat-shock protein family member of Theileria parva
Katende, J.M.Goddeeris, M.Morzaria, S.P.Nkonge, C.G.[Identification of Theileria mutans-specific antigen for use in antibody and antigen detection ELISA]Identification of Theileria mutans-specific antigen for use in antibody and antigen detection ELISA
Bishop, Richard P.Sohanpal, B.K.Morzaria, S.P.Dolan, T.T.Mwakima, F.N.Young, A.S.[Discrimination between Theileria parva and Theileria taurotragi in the salivary glands of Rhipicephalus appendiculatus ticks using oligonucleotides homologous to ribosomal RNA sequences]Discrimination between Theileria parva and Theileria taurotragi in the salivary glands of Rhipicephalus appendiculatus ticks using oligonucleotides homologous to ribosomal RNA sequences

East Coast fever (ECF), caused by Theileria parva, is the most important tick-borne disease of cattle in much of eastern, central and southern Africa. In Kenya, immunization against ECF has been performed in many field trials using the infection and treatment method. The main targets for immuniza...


Deem, S.L.Perry, Brian D.Katende, J.M.McDermott, John J.Mahan, S.M.Maloo, S.H.Morzaria, S.P.Musoke, A.J.Rowlands, G.J.[Variations in prevalence rates of tick-borne diseases in Zebu cattle by agroecological zone: Implications for East Coast fever immunization]Variations in prevalence rates of tick-borne diseases in Zebu cattle by agroecological zone: Implications for East Coast fever immunization

The most important tick-borne disease of cattle in eastern, central and southern Africa is East Coast fever (ECF) caused by Theileria parva and transmitted by the tick Rhipicephalus appendiculatus. Other less-important tick-borne diseases in cattle are benign theileriosis caused by Theileria muta...


Gitau, G.K.Perry, Brian D.Katende, J.M.McDermott, John J.Morzaria, S.P.Young, A.S.[The prevalence of serum antibodies to tick-borne infections in cattle in smallholder dairy farms in Murang'a District, Kenya; a cross-sectional study]The prevalence of serum antibodies to tick-borne infections in cattle in smallholder dairy farms in Murang'a District, Kenya; a cross-sectional study

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