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Murphy, N.B.Muthiani, C.Pandit, P.Kemei, S.Moloo, S.K.Hirumi, K.Hirumi, H.Peregrine, A.S.[The identification of genes of importance in Trypanosoma brucei brucei through the use of transfection techniques]The identification of genes of importance in Trypanosoma brucei brucei through the use of transfection techniques

Nuclear extrachromosomal DNA elements have been identified in several kinetoplastids such as Leishmania and Trypanosoma cruzi, but never in Trypanosoma brucei. They can occur naturally or arise spontaneously as the result of sublethal drug exposure of parasites. In most cases, they are represente...


Alsford, N.S.Navarro, M.Jamnadass, Ramni H.Dunbar, H.Ackroyd, M.Murphy, N.B.Gull, K.Ersfeld, K.[The identification of circular extrachromosomal DNA in the nuclear genome of Trypanosoma brucei]The identification of circular extrachromosomal DNA in the nuclear genome of Trypanosoma brucei
Dirie, M.F.Murphy, N.B.Gardiner, Peter R.[DNA fingerprinting of Trypanosoma vivax isolates rapidly identifies intraspecific relationships]DNA fingerprinting of Trypanosoma vivax isolates rapidly identifies intraspecific relationships
Leegwater, P.A.J.Strating, M.Murphy, N.B.Kooy, R.F.Vliet, P.C. van derOverdulve, J.P.[The Trypanosoma brucei DNA polymerase alpha core subunit gene is developmentally regulated and linked to a constitutively expressed open reading frame]The Trypanosoma brucei DNA polymerase alpha core subunit gene is developmentally regulated and linked to a constitutively expressed open reading frame
Waitumbi, J.N.Murphy, N.B.Peregrine, A.S.[Genotype and drug-resistance phenotype of Trypanosoma evansi originating from camels in Northern Kenya]Genotype and drug-resistance phenotype of Trypanosoma evansi originating from camels in Northern Kenya
Ndoutamia, G.Moloo, S.K.Murphy, N.B.Peregrine, A.S.[Derivation and characterization of a quinapyramine-resistant clone of Trypanosoma congolense]Derivation and characterization of a quinapyramine-resistant clone of Trypanosoma congolense
Welburn, S.C.Murphy, N.B.[Prohibitin proto-oncogene and RACK homologues are up-regulated in trypanosomes induced to undergo apoptosis and in naturally occurring terminally differentiated forms]Prohibitin proto-oncogene and RACK homologues are up-regulated in trypanosomes induced to undergo apoptosis and in naturally occurring terminally differentiated forms
Murphy, N.B.[Application of arbitrarily primed PCR fingerprinting to molecular studies on trypanosomes]Application of arbitrarily primed PCR fingerprinting to molecular studies on trypanosomes

Studies on infections with drug-resistant trypanosomes indicate that the majority of parasites in a population are sensitive to the drug dose used to select the population (Mamman et al., 1993). This study was initiated to examine whether a drug-resistant trypanosome population could influence th...


Burudi, E.M.E.Peregrine, A.S.Majiwa, P.A.O.Murphy, N.B.[Evaluation of response to treatment of mixed trypanosome infection in goats using the polymerase chain reaction]Evaluation of response to treatment of mixed trypanosome infection in goats using the polymerase chain reaction

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