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Fawcett, D.W.Musoke, A.J.Voigt, W.[Interaction of sporozoites of Theileria parva with bovine lymphocytes in vitro. 1. Early events after invasion]Interaction of sporozoites of Theileria parva with bovine lymphocytes in vitro. 1. Early events after invasion
Toye, Philip G.Goddeeris, M.Iams, K.P.Musoke, A.J.Morrison, W. Ivan[Characterization of a polymorphic immunodominant molecule in sporozoites and schizonts of Theileria parva]Characterization of a polymorphic immunodominant molecule in sporozoites and schizonts of Theileria parva
Shitakha, V.M.Nantulya, V.M.Musoke, A.J.Ramasamy, R.Buscher, G.[Complement activation and fibrinolysis during infection with Theileria parva (East Coast fever) in cattle]Complement activation and fibrinolysis during infection with Theileria parva (East Coast fever) in cattle

To evaluate vaccinia virus as a delivery system for recombinant antigen in cattle, calves were immunized with a recombinant vaccinia virus (rVV) expressing the sporozoite surface antigen (p67) of Theileria parva (V-67) combined with those expressing bovine IL-4 (V-IL4) or IL-2 (V-IL2). The anti-p...


Honda, Y.Waithaka, M.M.Taracha, E.L.N.Duchateau, L.Musoke, A.J.McKeever, Declan J.[Delivery of the Theileria parva p67 antigen to cattle using recombinant vaccinia virus: IL-2 enhances protection]Delivery of the Theileria parva p67 antigen to cattle using recombinant vaccinia virus: IL-2 enhances protection
Morzaria, S.P.Musoke, A.J.Latif, A.A.[Recognition of Theileria parva antigens by field sera from Rusinga Island Kenya]Recognition of Theileria parva antigens by field sera from Rusinga Island Kenya

Polymorphic, multicopy gene families are frequently located in subtelomeric regions of the genomes of parasitic protozoa. Theileria parva telomere-associated (TA) DNA from two chromosomes contained long open reading frames (ORFs) 54% identical at the N-termini whose ends were 2670 and 2680 bp fro...


Bishop, Richard P.Gobright, E.I.Nene, VishvanathMorzaria, S.P.Musoke, A.J.Sohanpal, B.K.[Polymorphic open reading frames encoding secretory proteins are located less than 3 kilobases from Theileria parva telomeres]Polymorphic open reading frames encoding secretory proteins are located less than 3 kilobases from Theileria parva telomeres

Theileria are economically important, intra-cellular protozoa, transmitted by ixodid ticks, which infect wild and domestic ruminants. In the mammalian host, parasites infect leukocytes and erythrocytes. In the arthropod vector they develop in gut epithelial cells and salivary glands. All four int...


Bishop, Richard P.Musoke, A.J.Morzaria, S.P.Gardner, M.Nene, Vishvanath[Theileria: Intracellular protozoan parasites of wild and domestic ruminants transmitted by ixodid ticks]Theileria: Intracellular protozoan parasites of wild and domestic ruminants transmitted by ixodid ticks

As a first step in developing compartment-specific markers for protein trafficking within Theileria parva, we have isolated cDNAs encoding homologues of the small GTP binding proteins Rab1 and Rab4. The T. parva homologue of Rab1 (TpRab1), a protein which regulates vesicular transport between the...


Janoo, R.T.K.Musoke, A.J.Wells, C.Bishop, Richard P.[A Rab1 homologue with a novel isoprenylation signal provides insight into the secretory pathway of Theileria parva]A Rab1 homologue with a novel isoprenylation signal provides insight into the secretory pathway of Theileria parva

Theileria annulata and Theileria parva both poses a major surface antigen on the sporozoite stage of the life-cycle, called SPAG-1 and p67, respectively. In each case, these antigens are vaccine candidates and have been shown to induce a degree of homologous protection in earlier work. These anti...


Hall, R.Boulter, N.R.Brown, C.G.D.Wilkie, G.Kirvar, E.Nene, VishvanathMusoke, A.J.Glass, E.J.Morzaria, S.P.[Reciprocal cross-protection induced by sporozoite antigens SPAG-1 from Theileria annulata and p67 from Theileria parva]Reciprocal cross-protection induced by sporozoite antigens SPAG-1 from Theileria annulata and p67 from Theileria parva

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