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Journal Article 2011-04-29

Autor: Pelle, Roger Graham, S.P. Njahira, Moses N. Osaso, J. Saya, R.M. Odongo, David O. Toye, Philip G. Spooner, P.R. Musoke, A.J. Mwangi, D.M. Taracha, E.L.N. Morrison, W. Ivan Weir, W. Silva, J. Bishop, Richard P.

Theileria parva causes an acute fatal disease in cattle, but infections are asymptomatic in the African buffalo (Syncerus caffer). Cattle can be immunized against the parasite by infection and treatment, but immunity is partially strain specific. Available data indicate that CD8+ T lymphocyte res...

Enlace original: https://cgspace.cgiar.org/handle/10568/3780

Investigación en Agricultura
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Pelle, Roger ,  Graham, S.P. ,  Njahira, Moses N. ,  Osaso, J. ,  Saya, R.M. ,  Odongo, David O. ,  Toye, Philip G. ,  Spooner, P.R. ,  Musoke, A.J. ,  Mwangi, D.M. ,  Taracha, E.L.N. ,  Morrison, W. Ivan ,  Weir, W. ,  Silva, J. ,  Bishop, Richard P. ,  [Two Theileria parva CD8 T Cell Antigen genes are more variable in buffalo than cattle parasites, but differ in pattern of sequence diversity] ,  Two Theileria parva CD8 T Cell Antigen genes are more variable in buffalo than cattle parasites, but differ in pattern of sequence diversity
Journal Article 2006-02-28

Autor: Graham, S.P. Pelle, Roger Honda, Y. Mwangi, D.M. Tonukari, N.J. Yamage, M. Glew, E.J. Villiers, Etienne P. de

East Coast fever, caused by the tick-borne intracellular apicomplexan parasite Theileria parva, is a highly fatal lymphoproliferative disease of cattle. The pathogenic schizont-induced lymphocyte transformation is a unique cancer-like condition that is reversible with parasite removal. Schizont-i...

Enlace original: https://cgspace.cgiar.org/handle/10568/1406

Investigación en Agricultura
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Graham, S.P. ,  Pelle, Roger ,  Honda, Y. ,  Mwangi, D.M. ,  Tonukari, N.J. ,  Yamage, M. ,  Glew, E.J. ,  Villiers, Etienne P. de ,  [Theileria parva candidate vaccine antigens recognized by immune bovine cytotoxic T lymphocytes] ,  Theileria parva candidate vaccine antigens recognized by immune bovine cytotoxic T lymphocytes
Journal Article 2007-02-09

Autor: Graham, S.P. Honda, Y. Pelle, Roger Mwangi, D.M. Glew, E.J. Villiers, Etienne P. de Shah, Tushaar Bishop, Richard P. Bruggen, P. van der Nene, Vishvanath Taracha, E.L.N.

Immunity against the bovine protozoan parasite Theileria parva has previously been shown to be mediated through lysis of parasite-infected cells by MHC class I restricted CD8+ cytotoxic T lymphocytes. It is hypothesized that identification of CTL target schizont antigens will aid the development ...

Enlace original: https://cgspace.cgiar.org/handle/10568/1394

Investigación en Agricultura
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Graham, S.P. ,  Honda, Y. ,  Pelle, Roger ,  Mwangi, D.M. ,  Glew, E.J. ,  Villiers, Etienne P. de ,  Shah, Tushaar ,  Bishop, Richard P. ,  Bruggen, P. van der ,  Nene, Vishvanath ,  Taracha, E.L.N. ,  [A novel strategy for the identification of antigens that are recognised by bovine MHC class I restricted cytotoxic T cells in a protozoan infection using reverse vaccinology] ,  A novel strategy for the identification of antigens that are recognised by bovine MHC class I restricted cytotoxic T cells in a protozoan infection using reverse vaccinology
Journal Article 1995

Autor: Mwangi, D.M. Hopkins, J. Luckins, A.G.

Events occurring in the skin of sheep prior to development of Trypanosoma congolense-induced local skin reactions (chancres) were studied using electron microscopy. Three days after infection, few trypanosomes were present in the dermal collagen. However, these parasites were more abundant 5 days...

Enlace original: https://cgspace.cgiar.org/handle/10568/35261

Investigación en Agricultura
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Mwangi, D.M. ,  Hopkins, J. ,  Luckins, A.G. ,  [Trypanosoma congolense infection in sheep: Ultrastructural changes in the skin prior to development of local skin reactions] ,  Trypanosoma congolense infection in sheep: Ultrastructural changes in the skin prior to development of local skin reactions
Journal Article 2011-04-15

Autor: Mwangi, D.M. Honda, Y. Graham, S.P. Pelle, Roger Taracha, E.L.N. Gachanja, J. Nyanjui, J.K. Bray, J. Palmer, G.H. Brown, W.C. Mwangi, W.

Theileria parva antigens recognized by cytotoxic T lymphocytes (CTLs) are prime vaccine candidates against East Coast Fever in cattle. A strategy for enhancing induction of parasite-specific T cell responses by increasing recruitment and activation of dendritic cells (DCs) at the immunization sit...

Enlace original: https://cgspace.cgiar.org/handle/10568/3074

Investigación en Agricultura
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Mwangi, D.M. ,  Honda, Y. ,  Graham, S.P. ,  Pelle, Roger ,  Taracha, E.L.N. ,  Gachanja, J. ,  Nyanjui, J.K. ,  Bray, J. ,  Palmer, G.H. ,  Brown, W.C. ,  Mwangi, W. ,  [Treatment of cattle with DNA-encoded Flt3L and GM-CSF prior to immunization with Theileria parva candidate vaccine antigens induces CD4 and CD8 T cell IFN-γ responses but not CTL responses] ,  Treatment of cattle with DNA-encoded Flt3L and GM-CSF prior to immunization with Theileria parva candidate vaccine antigens induces CD4 and CD8 T cell IFN-γ responses but not CTL responses

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