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Journal Article 2016-09-02

Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission

Autor: Olds, Cassandra L. Mwaura, S. Odongo, David O. Scoles, Glen A. Bishop, R. Daubenberger, C.A.

Background Rhipicephalus appendiculatus is the primary vector of Theileria parva, the etiological agent of East Coast fever (ECF), a devastating disease of cattle in sub-Saharan Africa. We hypothesized that a vaccine targeting tick proteins that are involved in attachment and feeding might affect...

Enlace original: https://cgspace.cgiar.org/handle/10568/80663

Investigación en Agricultura

ANTIGENS

CATTLE

DISEASE TRANSMISSION

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Olds, Cassandra L. , Mwaura, S. , Odongo, David O. , Scoles, Glen A. , Bishop, R. , Daubenberger, C.A. , [Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission] , Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission

Journal Article 2002-03-15

The persistence of Theileria parva infection in cattle immunised using two stocks which differ in their ability to induce a carrier state: Analysis using a novel blood spot PCR assay

Autor: Skilton, Robert A. Bishop, Richard P. Katende, J.M. Mwaura, S. Morzaria, S.P.

An improved Theileria parva DNA detection assay based on the polymerase chain reaction (PCR) using primers derived from the 104 kDa antigen (p104) gene was developed to detect parasite DNA in blood spots on filter paper. The specificity of the assay was validated using DNA from a wide range of ca...

Enlace original: https://cgspace.cgiar.org/handle/10568/21168

Investigación en Agricultura

VACCINES

CATTLE

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Skilton, Robert A. , Bishop, Richard P. , Katende, J.M. , Mwaura, S. , Morzaria, S.P. , [The persistence of Theileria parva infection in cattle immunised using two stocks which differ in their ability to induce a carrier state: Analysis using a novel blood spot PCR assay] , The persistence of Theileria parva infection in cattle immunised using two stocks which differ in their ability to induce a carrier state: Analysis using a novel blood spot PCR assay

Journal Article 2007-01-26

Vaccination of cattle with TickGARD induces cross-reactive antibodies binding to conserved linear peptides of Bm86 homologues in Boophilus decoloratus

Autor: Odongo, D. Kamau, L. Skilton, Robert A. Mwaura, S. Nitsch, C. Musoke, A.J. Taracha, E.A. Daubenberger, C.A. Bishop, Richard P.

Vaccines based on recombinant Bm86 gut antigen from Boophilus microplus are a useful component of integrated control strategies against B. microplus infestations of cattle. The capacity of such vaccines to control heterologous infestations by two African tick species was investigated. The mean we...

Enlace original: https://cgspace.cgiar.org/handle/10568/1557

Investigación en Agricultura

DISEASE CONTROL

VACCINES

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Odongo, D. , Kamau, L. , Skilton, Robert A. , Mwaura, S. , Nitsch, C. , Musoke, A.J. , Taracha, E.A. , Daubenberger, C.A. , Bishop, Richard P. , [Vaccination of cattle with TickGARD induces cross-reactive antibodies binding to conserved linear peptides of Bm86 homologues in Boophilus decoloratus] , Vaccination of cattle with TickGARD induces cross-reactive antibodies binding to conserved linear peptides of Bm86 homologues in Boophilus decoloratus

Journal Article 2011-02-15

Differential transcription of two highly divergent gut-expressed Bm86 antigen gene homologues in the tick Rhipicephalus appendiculatus (Acari: Ixodida)

Autor: Kamau, L. Skilton, Robert A. Odongo, David O. Mwaura, S. Githaka, Naftaly W. Kanduma, E.G. Obura, M. Kabiru, E. Orago, A. Musoke, A.J. Bishop, Richard P.

The transcriptional control of gene expression is not well documented in the Arthropoda. We describe transcriptional analysis of two exceptionally divergent homologues (Ra86) of the Bm86 gut antigen from Rhipicephalus appendiculatus. Bm86 forms the basis of a commercial vaccine for the control of...

Enlace original: https://cgspace.cgiar.org/handle/10568/2522

Investigación en Agricultura

RHIPICEPHALUS APPENDICULATUS

TICKS

ANTIGENS

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Kamau, L. , Skilton, Robert A. , Odongo, David O. , Mwaura, S. , Githaka, Naftaly W. , Kanduma, E.G. , Obura, M. , Kabiru, E. , Orago, A. , Musoke, A.J. , Bishop, Richard P. , [Differential transcription of two highly divergent gut-expressed Bm86 antigen gene homologues in the tick Rhipicephalus appendiculatus (Acari: Ixodida)] , Differential transcription of two highly divergent gut-expressed Bm86 antigen gene homologues in the tick Rhipicephalus appendiculatus (Acari: Ixodida)

Journal Article 2011-06-30

Molecular characterization of live Theileria parva sporozoite vaccine stabilates reveals extensive genotypic diversity

Autor: Patel, Ekta Lubembe, D.M. Gachanja, J. Mwaura, S. Spooner, P.R. Toye, Philip G.

The current Infection and Treatment Method of vaccination against East Coast fever comprises an inoculation of live Theileria parva sporozoites and simultaneous administration of oxytetracycline. Immunization with a combination of parasite types has been shown to provide broader protection than i...

Enlace original: https://cgspace.cgiar.org/handle/10568/3166

Investigación en Agricultura

THEILERIA PARVA

EAST COAST FEVER

VACCINES

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Patel, Ekta , Lubembe, D.M. , Gachanja, J. , Mwaura, S. , Spooner, P.R. , Toye, Philip G. , [Molecular characterization of live Theileria parva sporozoite vaccine stabilates reveals extensive genotypic diversity] , Molecular characterization of live Theileria parva sporozoite vaccine stabilates reveals extensive genotypic diversity

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Resultados de búsqueda

Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission

The persistence of Theileria parva infection in cattle immunised using two stocks which differ in their ability to induce a carrier state: Analysis using a novel blood spot PCR assay

Vaccination of cattle with TickGARD induces cross-reactive antibodies binding to conserved linear peptides of Bm86 homologues in Boophilus decoloratus

Differential transcription of two highly divergent gut-expressed Bm86 antigen gene homologues in the tick Rhipicephalus appendiculatus (Acari: Ixodida)

Molecular characterization of live Theileria parva sporozoite vaccine stabilates reveals extensive genotypic diversity

Descubre y comparte nuestro conocimiento público

Resultados de búsqueda

Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission

The persistence of Theileria parva infection in cattle immunised using two stocks which differ in their ability to induce a carrier state: Analysis using a novel blood spot PCR assay

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Vaccination of cattle with TickGARD induces cross-reactive antibodies binding to conserved linear peptides of Bm86 homologues in Boophilus decoloratus

Differential transcription of two highly divergent gut-expressed Bm86 antigen gene homologues in the tick Rhipicephalus appendiculatus (Acari: Ixodida)

Molecular characterization of live Theileria parva sporozoite vaccine stabilates reveals extensive genotypic diversity

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