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Journal Article 2009-05-01

Transcriptional profiling of cattle infected with Trypanosoma congolense highlights gene expression signatures underlying trypanotolerance and trypanosusceptibility

Autor: O'Gorman, G.M. Park, S. de Hill, E.W. Meade, K.G. Coussens, P.M. Agaba, Morris Naessens, Jan Kemp, Stephen J. MacHugh, D.E.

African animal trypanosomiasis (AAT) caused by tsetse fly-transmitted protozoa of the genus Trypanosoma is a major constraint on livestock and agricultural production in Africa and is among the top ten global cattle diseases impacting on the poor. Here we show that a functional genomics approach ...

Enlace original: https://cgspace.cgiar.org/handle/10568/45

Investigación en Agricultura

TRYPANOSOMA CONGOLENSE

TRYPANOSOMIASIS

EXPERIMENTATION

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O'Gorman, G.M. , Park, S. de , Hill, E.W. , Meade, K.G. , Coussens, P.M. , Agaba, Morris , Naessens, Jan , Kemp, Stephen J. , MacHugh, D.E. , [Transcriptional profiling of cattle infected with Trypanosoma congolense highlights gene expression signatures underlying trypanotolerance and trypanosusceptibility] , Transcriptional profiling of cattle infected with Trypanosoma congolense highlights gene expression signatures underlying trypanotolerance and trypanosusceptibility

Journal Article 2011-09-29

Efficacy of two vaccine formulations against contagious bovine pleuropneumonia (CBPP) in Kenyan indigenous cattle

Autor: Nkando, I. Ndinda, J. Kuria, J. Naessens, Jan Mbithi, F. Schnier, C. Gicheru, M. McKeever, Declan J. Wesonga, H.O.

A live, attenuated vaccine is currently the only viable option to control of CBPP in Africa. It has been suggested that simple modifications to current vaccines and protocols might improve efficacy in the field. In this report we compared the current vaccine formulation with a buffered preparatio...

Enlace original: https://cgspace.cgiar.org/handle/10568/16450

Investigación en Agricultura

VACCINES

DISEASE CONTROL

CATTLE

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Nkando, I. , Ndinda, J. , Kuria, J. , Naessens, Jan , Mbithi, F. , Schnier, C. , Gicheru, M. , McKeever, Declan J. , Wesonga, H.O. , [Efficacy of two vaccine formulations against contagious bovine pleuropneumonia (CBPP) in Kenyan indigenous cattle] , Efficacy of two vaccine formulations against contagious bovine pleuropneumonia (CBPP) in Kenyan indigenous cattle

Journal Article 2016-10-01

Capsular polysaccharide from Mycoplasma mycoides subsp.mycoides shows potential for protection against Contagious Bovine Pleuropneumonia

Autor: Mwirigi, M. Nkando, I. Olum, M. Attah-Poku, S. Ochanda, H. Berberov, E. Potter, A. Gerdts, V. Pérez Casal, J. Wesonga, H.O. Soi, R. Naessens, Jan

Contagious Bovine Pleuropneumonia (CBPP) is a severe respiratory disease caused byMycoplasma mycoides subsp. mycoides (Mmm) which is widespread in Africa. The capsule polysaccharide (CPS) of Mmm is one of the few identified virulence determinants. In a previous study, immunization of mice against...

Enlace original: https://cgspace.cgiar.org/handle/10568/76131

Investigación en Agricultura

ANIMAL DISEASES

DISEASE CONTROL

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Mwirigi, M. , Nkando, I. , Olum, M. , Attah-Poku, S. , Ochanda, H. , Berberov, E. , Potter, A. , Gerdts, V. , Pérez Casal, J. , Wesonga, H.O. , Soi, R. , Naessens, Jan , [Capsular polysaccharide from Mycoplasma mycoides subsp.mycoides shows potential for protection against Contagious Bovine Pleuropneumonia] , Capsular polysaccharide from Mycoplasma mycoides subsp.mycoides shows potential for protection against Contagious Bovine Pleuropneumonia

Journal Article 2018-10-15

Identification of targets of monoclonal antibodies that inhibit adhesion and growth in Mycoplasma mycoides subspecies mycoides

Autor: Aye, Racheal Weldearegay, Yenehiwot Berhanu Lutta, H.O. Chuma, Francis Pich, A. Jores, Joerg Meens, J. Naessens, Jan

Enlace original: https://cgspace.cgiar.org/handle/10568/98897

Investigación en Agricultura

ANTIBODIES

MYCOPLASMA

GROWTH INHIBITION

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Aye, Racheal , Weldearegay, Yenehiwot Berhanu , Lutta, H.O. , Chuma, Francis , Pich, A. , Jores, Joerg , Meens, J. , Naessens, Jan , [Identification of targets of monoclonal antibodies that inhibit adhesion and growth in Mycoplasma mycoides subspecies mycoides] , Identification of targets of monoclonal antibodies that inhibit adhesion and growth in Mycoplasma mycoides subspecies mycoides

Journal Article 2003

Responses of bovine chimaeras combining trypanosomosis resistant and susceptible genotypes to experimental infection with Trypanosoma congolense

Autor: Naessens, Jan Leak, S.G.A. Kennedy, D.J. Kemp, Stephen J. Teale, A.J.

West African N'Dama cattle have developed a genetic capacity to survive, reproduce and remain productive under trypanosomosis risk. The cellular and molecular bases of this so-called trypanotolerance are not known, but the trait is manifested by the N'Dama's greater capacity to control parasitae...

Enlace original: https://cgspace.cgiar.org/handle/10568/33227

Investigación en Agricultura

CATTLE

TRYPANOSOMIASIS

TRYPANOSOMA CONGOLENSE

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Naessens, Jan , Leak, S.G.A. , Kennedy, D.J. , Kemp, Stephen J. , Teale, A.J. , [Responses of bovine chimaeras combining trypanosomosis resistant and susceptible genotypes to experimental infection with Trypanosoma congolense] , Responses of bovine chimaeras combining trypanosomosis resistant and susceptible genotypes to experimental infection with Trypanosoma congolense

Journal Article 1997

Nomenclature and characterization of leukocyte differentiation antigens in ruminants

Autor: Naessens, Jan Howard, C.J. Hopkins, J.

Three international workshops held over the past eight years have addressed the identification and nomenclature of leukocyte differentiation antigens in ruminants. This article explains the progress the workshops have made.

Enlace original: https://cgspace.cgiar.org/handle/10568/28728

Investigación en Agricultura

RUMINANTS

IMMUNOLOGY

CATTLE

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Naessens, Jan , Howard, C.J. , Hopkins, J. , [Nomenclature and characterization of leukocyte differentiation antigens in ruminants] , Nomenclature and characterization of leukocyte differentiation antigens in ruminants

Journal Article 2003

Local skin reaction (chancre) induced following inoculation of metacyclic trypanosomes in cattle by tsetse flies is dependent on CD4 T lymphocytes

Autor: Naessens, Jan Mwangi, D.M. Buza, J. Moloo, S.K.

The first visible response in livestock to the bite of a trypanosome-infected tsetse fly is the formation of a localized skin reaction, also known as a chancre. This is an inflammatory response in the skin associated with swelling and an influx of cells. It is thought to be associated with an a...

Enlace original: https://cgspace.cgiar.org/handle/10568/33088

Investigación en Agricultura

CATTLE

PHYTOMONAS

SKIN DISEASES

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Naessens, Jan , Mwangi, D.M. , Buza, J. , Moloo, S.K. , [Local skin reaction (chancre) induced following inoculation of metacyclic trypanosomes in cattle by tsetse flies is dependent on CD4 T lymphocytes] , Local skin reaction (chancre) induced following inoculation of metacyclic trypanosomes in cattle by tsetse flies is dependent on CD4 T lymphocytes

Journal Article 1985

De novo expression of T-cell markers on Theileria parva-transformed lymphoblasts in cattle

Autor: Naessens, Jan Newson, J. Bensaid, A. Teale, A.J. Magondu, J. Black, S.J.

Enlace original: https://cgspace.cgiar.org/handle/10568/28921

Investigación en Agricultura

GENETIC MARKERS

THEILERIA PARVA

ANIMAL DISEASES

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Naessens, Jan , Newson, J. , Bensaid, A. , Teale, A.J. , Magondu, J. , Black, S.J. , [De novo expression of T-cell markers on Theileria parva-transformed lymphoblasts in cattle] , De novo expression of T-cell markers on Theileria parva-transformed lymphoblasts in cattle

Journal Article 1993

Section 6.21. Biochemical characterization of three non-lineage antigens defined by workshop antibodies

Autor: Naessens, Jan Nthale, J.

Enlace original: https://cgspace.cgiar.org/handle/10568/29829

Investigación en Agricultura

ANTIGENS

ANTIBODIES

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Naessens, Jan , Nthale, J. , [Section 6.21. Biochemical characterization of three non-lineage antigens defined by workshop antibodies] , Section 6.21. Biochemical characterization of three non-lineage antigens defined by workshop antibodies

Journal Article 2005-01-28

TNF-a mediates the development of anaemia in a murine Trypanosoma brucei rhodesiense infection, but not the anaemia associated with a murine Trypanosoma congolense infection

Autor: Naessens, Jan Kitani, H. Nakamura, Y. Yagi, Y. Sekikawa, K. Iraqi, F.A.

Development of anaemia in inflammatory diseases is cytokine-mediated. Specifically, the levels of tumour necrosis factor-α (TNF-α), produced by activated macrophages, are correlated with severity of disease and anaemia in infections and chronic disease. In African trypanosomiasis, anaemia develop...

Enlace original: https://cgspace.cgiar.org/handle/10568/1434

Investigación en Agricultura

TRYPANOSOMIASIS

DISEASE CONTROL

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Naessens, Jan , Kitani, H. , Nakamura, Y. , Yagi, Y. , Sekikawa, K. , Iraqi, F.A. , [TNF-a mediates the development of anaemia in a murine Trypanosoma brucei rhodesiense infection, but not the anaemia associated with a murine Trypanosoma congolense infection] , TNF-a mediates the development of anaemia in a murine Trypanosoma brucei rhodesiense infection, but not the anaemia associated with a murine Trypanosoma congolense infection

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