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Presentation 2013

Autor: Svitek, Nicholas Steinaa, Lucilla Saya, R. Awino, Elias Nielsen, Morten Buus, Soren Nene, Vishvanath
Enlace original: https://cgspace.cgiar.org/handle/10568/79118

Investigación en Agricultura
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Svitek, Nicholas ,  Steinaa, Lucilla ,  Saya, R. ,  Awino, Elias ,  Nielsen, Morten ,  Buus, Soren ,  Nene, Vishvanath ,  [The quest for the needle (antigen) in the haystack (pathogen): Immunoinformatics to the rescue] ,  The quest for the needle (antigen) in the haystack (pathogen): Immunoinformatics to the rescue
Journal Article 2018-03-15

Autor: Nyagwange, James Tijhaar, Edwin Ternette, Nicola Mobegi, Fredrick Tretina, Kyle Silva, Joana C. Pelle, Roger Nene, Vishvanath

East Coast fever is a lymphoproliferative disease caused by the tick-borne protozoan parasite Theileria parva. The sporozoite stage of this parasite, harboured and released from the salivary glands of the tick Rhipicephalus appendiculatus during feeding, invades and establishes infection in bovin...

Enlace original: https://cgspace.cgiar.org/handle/10568/89911

Investigación en Agricultura
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Nyagwange, James ,  Tijhaar, Edwin ,  Ternette, Nicola ,  Mobegi, Fredrick ,  Tretina, Kyle ,  Silva, Joana C. ,  Pelle, Roger ,  Nene, Vishvanath ,  [Characterization of the Theileria parva sporozoite proteome] ,  Characterization of the Theileria parva sporozoite proteome
Book Chapter 2018

Autor: Kiara, Henry K. Steinaa, Lucilla Nene, Vishvanath Svitek, Nicholas

Theileria are important hemoprotozoan parasites of domestic and wild ruminants, transmitted by ixodid ticks leading to diseases which range from mild in apparent reactions to highly fatal diseases. Bovine-infecting T. parva and T. annulata and ovine-infecting T. lestoquardi are of major global ec...

Enlace original: https://cgspace.cgiar.org/handle/10568/96895

Investigación en Agricultura
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Kiara, Henry K. ,  Steinaa, Lucilla ,  Nene, Vishvanath ,  Svitek, Nicholas ,  [Theileria in ruminants] ,  Theileria in ruminants
Journal Article 2015-04-30

Autor: Svitek, Nicholas Nzau, Benjamin M. Steinaa, Lucilla Nene, Vishvanath

We have developed a polymerase chain reaction-sequence-specific primers-restriction fragment length polymorphism (PCR-SSP-RFLP) method to rapidly differentiate between the A18 and A18 variant (v) BoLA haplotypes and between A14 and A15/A15v BoLA haplotypes in Holstein/Friesian cattle. We used pub...

Enlace original: https://cgspace.cgiar.org/handle/10568/66014

Investigación en Agricultura
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Svitek, Nicholas ,  Nzau, Benjamin M. ,  Steinaa, Lucilla ,  Nene, Vishvanath ,  [A method to discriminate between closely related bovine major histocompatibility complex class I alleles by combining established PCR-SSP assays with RFLPs] ,  A method to discriminate between closely related bovine major histocompatibility complex class I alleles by combining established PCR-SSP assays with RFLPs
Journal Article 2014-09-23

Autor: Wendoh, J. Waihenya, R. Saya, R. Awino, Elias Nene, Vishvanath Steinaa, Lucilla

Theileria parva is a protozoan parasite that causes the disease East Coast fever in cattle which results in major economic losses in Eastern, Central and Southern Africa. Efforts to generate vaccines involve measurements of cytotoxic activity since CD8 cells are believed to be responsible for pro...

Enlace original: https://cgspace.cgiar.org/handle/10568/56588

Investigación en Agricultura
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Wendoh, J. ,  Waihenya, R. ,  Saya, R. ,  Awino, Elias ,  Nene, Vishvanath ,  Steinaa, Lucilla ,  [Perforin expression in Theileria parva specific Cytotoxic T Cells correlates with Cytotoxicity] ,  Perforin expression in Theileria parva specific Cytotoxic T Cells correlates with Cytotoxicity
Journal Article 2012-06-15

Autor: Nene, Vishvanath Svitek, Nicholas Toye, Philip G. Golde, W.T. Barlow, J. Buus, Soren Nielsen, Morten

T cell responses contribute to immunity against many intracellular infections. There is, for example, strong evidence that major histocompatibility complex (MHC) class I-restricted cytotoxic T lymphocytes (CTLs) play an essential role in mediating immunity to East Coast fever (ECF), a fatal lymph...

Enlace original: https://cgspace.cgiar.org/handle/10568/16432

Investigación en Agricultura
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Nene, Vishvanath ,  Svitek, Nicholas ,  Toye, Philip G. ,  Golde, W.T. ,  Barlow, J. ,  Buus, Soren ,  Nielsen, Morten ,  [Designing bovine T cell vaccines via reverse immunology] ,  Designing bovine T cell vaccines via reverse immunology
Journal Article 2013-09-15

Autor: Heekin, A.M. Guerrero, F.D. Bendele, K.G. Saldivar, L. Scoles, Glen A. Dowd, S.E. Gondro, C. Nene, Vishvanath Djikeng, Appolinaire Brayton, K.A.

As it feeds upon cattle, Rhipicephalus (Boophilus) microplus is capable of transmitting a number of pathogenic organisms, including the apicomplexan hemoparasite Babesia bovis, a causative agent of bovine babesiosis. The R. microplus female gut transcriptome was studied for two cohorts: adult fem...

Enlace original: https://cgspace.cgiar.org/handle/10568/35307

Investigación en Agricultura
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Heekin, A.M. ,  Guerrero, F.D. ,  Bendele, K.G. ,  Saldivar, L. ,  Scoles, Glen A. ,  Dowd, S.E. ,  Gondro, C. ,  Nene, Vishvanath ,  Djikeng, Appolinaire ,  Brayton, K.A. ,  [Gut transcriptome of replete adult female cattle ticks, Rhipicephalus (Boophilus) microplus, feeding upon a Babesia bovis-infected bovine host] ,  Gut transcriptome of replete adult female cattle ticks, Rhipicephalus (Boophilus) microplus, feeding upon a Babesia bovis-infected bovine host
Poster 2016-05-22

Autor: Nyagwange, James Ternette, Nicola Tijhaar, Edwin Pelle, Roger Nene, Vishvanath
Enlace original: https://cgspace.cgiar.org/handle/10568/75993

Investigación en Agricultura
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Nyagwange, James ,  Ternette, Nicola ,  Tijhaar, Edwin ,  Pelle, Roger ,  Nene, Vishvanath ,  [Proteomics of Theileria parva sporozoites] ,  Proteomics of Theileria parva sporozoites
Journal Article 2014-04-28

Autor: Svitek, Nicholas Hansen, A.M. Steinaa, Lucilla Saya, R. Awino, Elias Nielsen, Morten Buus, Soren Nene, Vishvanath

Peptide-major histocompatibility complex (p-MHC) class I tetramer complexes have facilitated the early detection and functional characterisation of epitope specific CD8+ cytotoxic T lymphocytes (CTL). Here, we report on the generation of seven recombinant bovine leukocyte antigens (BoLA) and reco...

Enlace original: https://cgspace.cgiar.org/handle/10568/41612

Investigación en Agricultura
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Svitek, Nicholas ,  Hansen, A.M. ,  Steinaa, Lucilla ,  Saya, R. ,  Awino, Elias ,  Nielsen, Morten ,  Buus, Soren ,  Nene, Vishvanath ,  [Use of “one-pot, mix-and-read” peptide-MHC class I tetramers and predictive algorithms to improve detection of cytotoxic T lymphocyte responses in cattle] ,  Use of “one-pot, mix-and-read” peptide-MHC class I tetramers and predictive algorithms to improve detection of cytotoxic T lymphocyte responses in cattle

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