Flow cytometry, enzyme-linked immunospot (ELISpot) and cellular cytotoxicity assays are powerful tools for studying the cellular immune response towards intracellular pathogens and vaccines in livestock species. Lymphocytes from immunized animals can be purified using Ficoll-Paque density gradien...
Svitek, Nicholas
,
Taracha, E.L.N.
,
Saya, R.
,
Awino, Elias
,
Nene, Vishvanath
,
Steinaa, Lucilla
,
[Analysis of the cellular immune responses to vaccines]
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Analysis of the cellular immune responses to vaccines
Bishop, Richard P.
,
Musoke, A.J.
,
Skilton, Robert A.
,
Morzaria, S.P.
,
Gardner, M.
,
Nene, Vishvanath
,
[Theileria: Life cycle stages associated with the ixodid tick vector]
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Theileria: Life cycle stages associated with the ixodid tick vector
Nene, Vishvanath
,
Bishop, Richard P.
,
Quackenbush, J.
,
Pertea, M.
,
Salzberg, S.L.
,
Taracha, E.A.
,
Morzaria, S.P.
,
Fraser, C.M.
,
Gardner, M.
,
[Genomics of Theileria parva]
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Genomics of Theileria parva
The Development of a recombinant Theileria parva vaccine is discussed under the following headings: mechanisms of protection against ECF [East Coast fever]; cloning and expression of p67; immunization and challenge of cattle; interpretation of immunization and challenge data.
Musoke, A.J.
,
McKeever, Declan J.
,
Morzaria, S.P.
,
Nkonge, C.
,
Nene, Vishvanath
,
[A recombinant vaccine for Theileria parva]
,
A recombinant vaccine for Theileria parva
Musoke, A.J.
,
Nene, Vishvanath
,
McKeever, Declan J.
,
[Epitope specificity of bovine immune responses to the major surface antigen of Theileria parva sporozoites]
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Epitope specificity of bovine immune responses to the major surface antigen of Theileria parva sporozoites
Bishop, Richard P.
,
Geysen, D.
,
Skilton, Robert A.
,
Odongo, D.
,
Nene, Vishvanath
,
Allsopp, B.A.
,
Mbogo, S.
,
Spooner, P.R.
,
Morzaria, S.P.
,
[Genomic polymorphism, sexual recombination and molecular epidemiology of Theileria parva]
,
Genomic polymorphism, sexual recombination and molecular epidemiology of Theileria parva
Theileria are important hemoprotozoan parasites of domestic and wild ruminants, transmitted by ixodid ticks leading to diseases which range from mild in apparent reactions to highly fatal diseases. Bovine-infecting T. parva and T. annulata and ovine-infecting T. lestoquardi are of major global ec...