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Dry mouth sensation, also known as xerostomia, is a common clinical problem with an increasing prevalence. Although recent studies have reported promissory results of malic acid, none have evaluated the impact of malic acid on the oral health-related quality of life (OHRQoL) of patients with xero...


Niklander, S.Fuentes, F.Sanchez, D.Araya, V.Chiappini, G.Martinez, R.Marshall, M.[Impact of 1% malic acid spray on the oral health-related quality of life of patients with xerostomia]Impact of 1% malic acid spray on the oral health-related quality of life of patients with xerostomia

To determine xerostomia-related frequency, factors, salivary flow rates and Oral Health-Related Quality of Life (OHRQoL) of patients attending the Universidad Andrés Bello Dental School Clinic, in the city of Viña del Mar, Chile. The study involved 566 patients assessed with xerostomia, based on ...


Niklander, S.Veas, L.Barrera, C.Fuentes, F.Chiappini, G.Marshall, M.[Risk factors, hyposalivation and impact of xerostomia on oral health-related quality of life]Risk factors, hyposalivation and impact of xerostomia on oral health-related quality of life

To evaluate the expression of the epidermal growth factor receptor (EGFR) and mean vascular density (MVD) in normal oral mucosa (NOM), oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC). Material and methods: Descriptive case study. Nineteen histological samples diagnosed wit...


Fernández, A.Fernández, J.Marshall, M.Martínez, R.Niklander, S.Haidar, Z.S.[Difference in EGFR expression and mean vascular density in normal oral mucosa, oral epithelial dysplasia and oral squamous cell carcinoma]Difference in EGFR expression and mean vascular density in normal oral mucosa, oral epithelial dysplasia and oral squamous cell carcinoma

Backgroud: A considerable number of gastrointestinal disorders (GIDs) of varied nature (inflammatory, infectious, genetic and other etiology) may produce alterations in the hard and soft oral tissues. Among these are Crohn's disease, ulcerative colitis, celiac and gastroesophageal reflux disease....


Jajam, M.Bozzolo, P.Niklander, S.[Oral manifestations of gastrointestinal disorders]Oral manifestations of gastrointestinal disorders

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