Rift Valley Fever virus (RVFV) causes recurrent outbreaks of acute life-threatening human and livestock illness in Africa and the Arabian Peninsula. No licensed vaccines are currently available for humans and those widely used in livestock have major safety concerns. A ‘One Health’ vaccine develo...
Warimwe, G.M.
,
Gesharisha, J.
,
Carr, B.V.
,
Otieno, S.
,
Otingah, K.
,
Wright, D.
,
Charleston, B.
,
Okoth, Edward A.
,
Elena, L.G.
,
Lorenzo, G.
,
Ayman, E.B.
,
Alharbi, N.K.
,
Al-Dubaib, M.A.
,
Brun, A.
,
Gilbert, S.C.
,
Nene, Vishvanath
,
Hill, A.V.S.
,
[Chimpanzee adenovirus vaccine provides multispecies protection against Rift Valley fever]
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Chimpanzee adenovirus vaccine provides multispecies protection against Rift Valley fever
Amimo, Joshua O.
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Machuka, E.M.
,
Okoth, Edward A.
,
[First detection of rotavirus group C in asymptomatic pigs of smallholder farms in East Africa]
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First detection of rotavirus group C in asymptomatic pigs of smallholder farms in East Africa
We describe a horizontal survey of African swine fever virus (ASFV) prevalence and risk factors associated with virus infection in domestic pigs in two contrasting production systems in Kenya. A free range/tethering, low input production system in Ndhiwa District of South-western Kenya is compare...
Okoth, Edward A.
,
Gallardo, C.
,
Macharia, J.M.
,
Omore, Amos O.
,
Pelayo, V.
,
Bulimo, D.W.
,
Arias, Marisa
,
Kitala, P.
,
Baboon, K.
,
Lekolol, I.
,
Mijele, D.
,
Bishop, Richard P.
,
[Comparison of African swine fever virus prevalence and risk in two contrasting pig-farming systems in South-west and Central Kenya]
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Comparison of African swine fever virus prevalence and risk in two contrasting pig-farming systems in South-west and Central Kenya
A cross-sectional survey was carried out to assess risk factors associated with occurrence of African swine fever (ASF) outbreaks in smallholder pig farms in four districts along Kenya-Uganda border. Information was collected by administering questionnaires to 642 randomly selected pig households...
Nantima, Noelina
,
Ocaido, M.
,
Ouma, Emily A.
,
Davies, J.
,
Dione, Michel M.
,
Okoth, Edward A.
,
Mugisha, A.
,
Bishop, Richard P.
,
[Risk factors associated with occurrence of African swine fever outbreaks in smallholder pig farms in four districts along the Uganda-Kenya border]
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Risk factors associated with occurrence of African swine fever outbreaks in smallholder pig farms in four districts along the Uganda-Kenya border
The presence of antibodies against African swine fever (ASF), a complex fatal notifiable OIE disease of swine, is always indicative of previous infection, since there is no vaccine that is currently used in the field. The early appearance and subsequent long-term persistence of antibodies combine...
Gallardo, C.
,
Soler Garzón, Alvaro
,
Nieto, R.
,
Carrascosa, A.L.
,
Mia, G.M. de
,
Bishop, Richard P.
,
Martins, C.
,
Fasina, F.O.
,
Couacy-Hyman, E.
,
Heath, L.
,
Pelayo, V.
,
Martin, E.
,
Simon, A.
,
Martin, R.
,
Okurut, A.R.
,
Lekolol, I.
,
Okoth, Edward A.
,
Arias, Marisa
,
[Comparative evaluation of novel African swine fever virus (ASF) antibody detection techniques derived from specific ASF viral genotypes with the OIE internationally prescribed serological tests]
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Comparative evaluation of novel African swine fever virus (ASF) antibody detection techniques derived from specific ASF viral genotypes with the OIE internationally prescribed serological tests
Twelve complete African swine fever virus (ASFV) genome sequences are currently publicly available and these include only one sequence from East Africa. We describe genome sequencing and annotation of a recent pig-derived p72 genotype IX, and a tick-derived genotype X isolate from Kenya using the...
Bishop, Richard P.
,
Fleischauer, C.
,
Villiers, Etienne P. de
,
Okoth, Edward A.
,
Arias, Marisa
,
Gallardo, C.
,
Upton, C.
,
[Comparative analysis of the complete genome sequences of Kenyan African swine fever virus isolates within p72 genotypes IX and X]
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Comparative analysis of the complete genome sequences of Kenyan African swine fever virus isolates within p72 genotypes IX and X
Orono, S.A.
,
Gitao, G.C.
,
Mpatswenumugabo, J.P.
,
Chepkwony, M.
,
Mutisya, Christine N.
,
Okoth, Edward A.
,
Bronsvoort, B.M.C. de
,
Russell, G.C.
,
Nene, Vishvanath
,
Cook, Elizabeth A.J.
,
[Field validation of clinical and laboratory diagnosis of wildebeest associated malignant catarrhal fever in cattle]
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Field validation of clinical and laboratory diagnosis of wildebeest associated malignant catarrhal fever in cattle
The central variable region (CVR) within the B602L gene of the African swine fever virus (ASFV) is highly polymorphic within the 23 ASFV genotypes defined by sequencing of the C-terminal end of the p72 locus. Sequencing the p54 gene further discriminates ASFV genotypes that are conserved at the p...
Onzere, Cynthia K.
,
Bastos, A.D.S.
,
Okoth, Edward A.
,
Lichoti, J.K.
,
Nyambego, Edwina B.
,
Owido, M.G.
,
Ndambuki, Gideon M.
,
Bronsvoort, B.M. de C.
,
Bishop, Richard P.
,
[Multi-locus sequence typing of African swine fever viruses from endemic regions of Kenya and Eastern Uganda (2011–2013) reveals rapid B602L central variable region evolution]
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Multi-locus sequence typing of African swine fever viruses from endemic regions of Kenya and Eastern Uganda (2011–2013) reveals rapid B602L central variable region evolution