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Conference Paper 1995

Autor: Eisler, M.C. Maloo, S.H. Peregrine, A.S. Holmes, P.H. Thorpe, W.R.

Isometamidium chloride is the most important chemoprophylactic agent used in the control of African bovine trypanosomiasis, although breakdowns in prophylaxis have been observed in the field. It is not usually apparent whether these breakdowns are due to inadequate drug dosage regimens, or to the...

Enlace original: https://cgspace.cgiar.org/handle/10568/51297

Investigación en Agricultura
Enlace permanente
Eisler, M.C. ,  Maloo, S.H. ,  Peregrine, A.S. ,  Holmes, P.H. ,  Thorpe, W.R. ,  [Use of the isometamidium Elisa to measure serum concentrations of the drug in Jersey dairy cattle in Kenya] ,  Use of the isometamidium Elisa to measure serum concentrations of the drug in Jersey dairy cattle in Kenya
Conference Paper 1995

Autor: Mamman, M. McKeever, Declan J. Peregrine, A.S.

A study was undertaken to compare the absorption and distribution of the antitrypanosomal drug diminazene aceturate in plasma, cerebrospinal fluid (CSF) and lymph of goats. The study comprised three groups of three goats each. Animals in each group were treated with a single intramuscular dose of...

Enlace original: https://cgspace.cgiar.org/handle/10568/50293

Investigación en Agricultura
Enlace permanente
Mamman, M. ,  McKeever, Declan J. ,  Peregrine, A.S. ,  [Comparative pharmacokinetics of diminazene in plasma, cerebrospinal fluid and lymph of goats] ,  Comparative pharmacokinetics of diminazene in plasma, cerebrospinal fluid and lymph of goats
Conference Paper 1995

Autor: Peregrine, A.S. Eisler, M.C. Flynn, J.N. Katende, J. Gault, E.A. Kinabo, L.D.B. Homes, P.H.

Isometamidium chloride (Samorin, Trypanidium is a phenanthridine-aromatic amidine that is commonly used in cattle as a prophylactic agent against trypanosomiasis. Although the compound has been used for over 30 years, very little is known about its mode of action. Various workers have demonstrate...

Enlace original: https://cgspace.cgiar.org/handle/10568/50578

Investigación en Agricultura
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Peregrine, A.S. ,  Eisler, M.C. ,  Flynn, J.N. ,  Katende, J. ,  Gault, E.A. ,  Kinabo, L.D.B. ,  Homes, P.H. ,  [Generation of monoclonal antibodies to the anti-trypanosomal drug Samorin] ,  Generation of monoclonal antibodies to the anti-trypanosomal drug Samorin
Conference Paper 2000

Autor: Geerts, S. Ndung'u, J.M. Murilla, G. Mbwambo, H. Sirryangwe, L. Machila, N. Delespaux, V. Brandt, J. Peregrine, A.S. McDermott, John J. Holmes, P.H. Eisler, M.C.

Besides the in vitro test, two tests are very commonly used for the detection of trypanocidal drug resistance: the tests in mice and in ruminants. Since it has been shown that several parameters such as the number of trypanosomes inoculated and the time of treatment might influence the outcome of...

Enlace original: https://cgspace.cgiar.org/handle/10568/50712

Investigación en Agricultura
Enlace permanente
Geerts, S. ,  Ndung'u, J.M. ,  Murilla, G. ,  Mbwambo, H. ,  Sirryangwe, L. ,  Machila, N. ,  Delespaux, V. ,  Brandt, J. ,  Peregrine, A.S. ,  McDermott, John J. ,  Holmes, P.H. ,  Eisler, M.C. ,  [In vivo tests for the detection of resistance to trypanocidal drugs: Tests in mice and in ruminants] ,  In vivo tests for the detection of resistance to trypanocidal drugs: Tests in mice and in ruminants

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