Experiments were carried out in goats to determine the frequency with which diminazene-resistant trypanosomes occur in parasite populations before and after the intramuscular treatment of the goats with diminazene aceturate. Trypanosoma congolense IL3274, a diminazene-resistant clone, was used to...
Mamman, M.
,
Williams, D.J.L.
,
Murphy, N.B.
,
Peregrine, A.S.
,
[Apparent rarity of diminazene-resistant trypanosomes in goats infected with a diminazene-resistant population of Trypanosoma congolense]
,
Apparent rarity of diminazene-resistant trypanosomes in goats infected with a diminazene-resistant population of Trypanosoma congolense
Mamman, M.
,
Katende, J.
,
Moloo, S.K.
,
Peregrine, A.S.
,
[Variation in sensitivity of Trypanosoma congolense to diminazene during the early phase of tsetse-transmitted infection in goats]
,
Variation in sensitivity of Trypanosoma congolense to diminazene during the early phase of tsetse-transmitted infection in goats
Diminazene aceturate is one of a limited number of drugs currently being used in animals to treat the tsetse fly-transmitted protozoal disease, African trypanosomiasis. Efficacy of the drug at the recommended single IM administered doses of 3.5 and 7.0 mg/kg of body weight is widely acknowledged....
Mamman, M.
,
McKeever, Declan J.
,
Aliu, Y.O.
,
Peregrine, A.S.
,
[Pharmacokinetics of diminazene in plasma and lymph of goats]
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Pharmacokinetics of diminazene in plasma and lymph of goats
Peregrine, A.S.
,
Mamman, M.
,
[A simple method for repeated sampling of lumbar cerebrospinal fluid in goats]
,
A simple method for repeated sampling of lumbar cerebrospinal fluid in goats
Silayo, R.S.
,
Mamman, M.
,
Moloo, S.K.
,
Aliu, Y.O.
,
Gray, M.A.
,
Peregrine, A.S.
,
[Response of Trypanosoma congolense in goats to single and double treatment with diminazene aceturate]
,
Response of Trypanosoma congolense in goats to single and double treatment with diminazene aceturate
Mamman, M.
,
Peregrine, A.S.
,
[Pharmacokinetics of dimenazene in plasma and cerebrospinal fluid of goats]
,
Pharmacokinetics of dimenazene in plasma and cerebrospinal fluid of goats
A study was carried out to determine whether a drug-resistant trypanosome population could influence the survival of a drug-sensitive population in mixed infections in goats. To identify both populations during the course of a mixed infection, a system for distinguishing them was developed; using...
Burudi, E.M.E.
,
Peregrine, A.S.
,
Majiwa, P.A.O.
,
Mbiuki, S.M.
,
Murphy, N.B.
,
[Response of diminazene-resistance and diminazene-susceptible Trypanosoma congolense to treatment with diminazene when occuring as a mixed infection in goats]
,
Response of diminazene-resistance and diminazene-susceptible Trypanosoma congolense to treatment with diminazene when occuring as a mixed infection in goats
Mamman, M.
,
Moloo, S.K.
,
Peregrine, A.S.
,
[Relapse of Trypanosoma congolense infection in goats after diminazene aceturate is not a result of invasion of the central nervous system]
,
Relapse of Trypanosoma congolense infection in goats after diminazene aceturate is not a result of invasion of the central nervous system