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Article 2017-08

Chronic Stress Triggers Expression of Immediate Early Genes and Differentially Affects the Expression of AMPA and NMDA Subunits in Dorsal and Ventral Hippocampus of Rats

Autor: Pacheco, A. Aguayo, F.I. Aliaga, E. Muñoz, M. García-Rojo, G. Olave, F.A. Parra-Fiedler, N.A. García-Pérez, A. Tejos-Bravo, M. Rojas, P.S. Parra, C.S. Fiedler, J.L.

Previous studies in rats have demonstrated that chronic restraint stress triggers anhedonia, depressive-like behaviors, anxiety and a reduction in dendritic spine density in hippocampal neurons. In this study, we compared the effect of repeated stress on the expression of α-amino-3-hydroxy-5-meth...

Enlace original: http://repositorio.unab.cl/xmlui/handle/ria/5235

Repositorio Universidad Andrés Bello

AMPA receptor subunits

Arc

C-Fos

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Pacheco, A. , Aguayo, F.I. , Aliaga, E. , Muñoz, M. , García-Rojo, G. , Olave, F.A. , Parra-Fiedler, N.A. , García-Pérez, A. , Tejos-Bravo, M. , Rojas, P.S. , Parra, C.S. , Fiedler, J.L. , [Chronic Stress Triggers Expression of Immediate Early Genes and Differentially Affects the Expression of AMPA and NMDA Subunits in Dorsal and Ventral Hippocampus of Rats] , Chronic Stress Triggers Expression of Immediate Early Genes and Differentially Affects the Expression of AMPA and NMDA Subunits in Dorsal and Ventral Hippocampus of Rats

Article 2017-04

The ROCK inhibitor Fasudil prevents chronic restraint stress-induced depressive-like behaviors and dendritic spine loss in rat hippocampus

Autor: García-Rojo, G. Fresno, C. Vilches, N. Díaz-Véliz, G. Mora, S. Aguayo, F. Pacheco, A. Parra-Fiedler, N. Parra, C.S. Rojas, P.S. Tejos, M. Aliaga, E. Fiedler, J.L.

Background: Dendritic arbor simplification and dendritic spine loss in the hippocampus, a limbic structure implicated in mood disorders, are assumed to contribute to symptoms of depression. These morphological changes imply modifications in dendritic cytoskeleton. Rho GTPases are regulators of ac...

Enlace original: http://repositorio.unab.cl/xmlui/handle/ria/4722

Repositorio Universidad Andrés Bello

Antidepressant

Behavior Dendritic spines

ROCK inhibitor Fasudil

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García-Rojo, G. , Fresno, C. , Vilches, N. , Díaz-Véliz, G. , Mora, S. , Aguayo, F. , Pacheco, A. , Parra-Fiedler, N. , Parra, C.S. , Rojas, P.S. , Tejos, M. , Aliaga, E. , Fiedler, J.L. , [The ROCK inhibitor Fasudil prevents chronic restraint stress-induced depressive-like behaviors and dendritic spine loss in rat hippocampus] , The ROCK inhibitor Fasudil prevents chronic restraint stress-induced depressive-like behaviors and dendritic spine loss in rat hippocampus

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Resultados de búsqueda

Chronic Stress Triggers Expression of Immediate Early Genes and Differentially Affects the Expression of AMPA and NMDA Subunits in Dorsal and Ventral Hippocampus of Rats

The ROCK inhibitor Fasudil prevents chronic restraint stress-induced depressive-like behaviors and dendritic spine loss in rat hippocampus

Descubre y comparte nuestro conocimiento público

Resultados de búsqueda

Chronic Stress Triggers Expression of Immediate Early Genes and Differentially Affects the Expression of AMPA and NMDA Subunits in Dorsal and Ventral Hippocampus of Rats

[Pacheco_A_Chronic_Stress_Triggers.pdf]

The ROCK inhibitor Fasudil prevents chronic restraint stress-induced depressive-like behaviors and dendritic spine loss in rat hippocampus

[Garcia-Rojo_The_rock_inhibitor.pdf]