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Journal Article 2001

Autor: Sileghem, M.R. Saya, R. Grab, D.J. Naessens, Jan

The membrane-associated form of the variable surface glycoprotein (mfVSG) from African trypanosomes is a potent macrophage activator capable of inducing production of tumor necrosis factor z (TNFalfa) in both bovine and murine models. Using a bovine model. we have re-investigated the hypothesis t...

Enlace original: https://cgspace.cgiar.org/handle/10568/33224

Investigación en Agricultura
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Sileghem, M.R. ,  Saya, R. ,  Grab, D.J. ,  Naessens, Jan ,  [An accessory role for the diacylglycerol moiety of variable surface glycoprotein of African trypanosomes in the simulation of bovine monocytes] ,  An accessory role for the diacylglycerol moiety of variable surface glycoprotein of African trypanosomes in the simulation of bovine monocytes
Journal Article 2007

Autor: Graham, S.P. Saya, R. Awino, Elias Ngugi, D. Nyanjui, J.K. Hecker, R. Taracha, E.L.N. Nene, Vishvanath

Enhancement of the induction of cytotoxic T-cell responses by immunostimulatory CpG oligodeoxynucleotides has been described in humans and mouse models. The present study attempted to address whether CpG has a similar effect in cattle. Immunisation of cattle with a recombinant form of the polymor...

Enlace original: https://cgspace.cgiar.org/handle/10568/33218

Investigación en Agricultura
Enlace permanente
Graham, S.P. ,  Saya, R. ,  Awino, Elias ,  Ngugi, D. ,  Nyanjui, J.K. ,  Hecker, R. ,  Taracha, E.L.N. ,  Nene, Vishvanath ,  [Immunostimulatory CpG oligodeoxynucleotides enhance the induction of bovine CD4+ cytotoxic T-lymphocyte responses against the polymorphic immunodominant molecule of the protozoan parasite Theileria parva] ,  Immunostimulatory CpG oligodeoxynucleotides enhance the induction of bovine CD4+ cytotoxic T-lymphocyte responses against the polymorphic immunodominant molecule of the protozoan parasite Theileria parva
Journal Article 2012-02-15

Autor: Steinaa, Lucilla Saya, R. Awino, Elias Toye, Philip G.

The protozoan parasite Theileria parva causes a usually fatal disease in cattle, known as East Coast fever. Cattle can be vaccinated by injecting live parasites simultaneously with long acting oxytetracycline (the Infection and Treatment Method, ITM). The immunity induced by ITM is believed to be...

Enlace original: https://cgspace.cgiar.org/handle/10568/16380

Investigación en Agricultura
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Steinaa, Lucilla ,  Saya, R. ,  Awino, Elias ,  Toye, Philip G. ,  [Cytotoxic T lymphocytes from cattle immunized against Theileria parva exhibit pronounced cross-reactivity among different strain-specific epitopes of the Tp1 antigen] ,  Cytotoxic T lymphocytes from cattle immunized against Theileria parva exhibit pronounced cross-reactivity among different strain-specific epitopes of the Tp1 antigen
Journal Article 2014-04-28

Autor: Svitek, Nicholas Hansen, A.M. Steinaa, Lucilla Saya, R. Awino, Elias Nielsen, Morten Buus, Soren Nene, Vishvanath

Peptide-major histocompatibility complex (p-MHC) class I tetramer complexes have facilitated the early detection and functional characterisation of epitope specific CD8+ cytotoxic T lymphocytes (CTL). Here, we report on the generation of seven recombinant bovine leukocyte antigens (BoLA) and reco...

Enlace original: https://cgspace.cgiar.org/handle/10568/41612

Investigación en Agricultura
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Svitek, Nicholas ,  Hansen, A.M. ,  Steinaa, Lucilla ,  Saya, R. ,  Awino, Elias ,  Nielsen, Morten ,  Buus, Soren ,  Nene, Vishvanath ,  [Use of “one-pot, mix-and-read” peptide-MHC class I tetramers and predictive algorithms to improve detection of cytotoxic T lymphocyte responses in cattle] ,  Use of “one-pot, mix-and-read” peptide-MHC class I tetramers and predictive algorithms to improve detection of cytotoxic T lymphocyte responses in cattle

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