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Vecchiola Cárdenas, Andrea Paola.Lagos Arévalo, Carlos Fernando.Fuentes, Cristóbal A.Allende, Fidel.Campino Johnson, María del Carmen.Valdivia, Carolina.Tapia Castillo, Alejandra.Owen, Gareth Ivor.Solari Gajardo, Sandra.Carvajal Maldonado, Cristián Andrés.Fardella B., Carlos.Ogishima, Tadashi.Mukai, Kuniaki.[Different effects of progesterone and estradiol on chimeric and wild type aldosterone synthase in vitro]Different effects of progesterone and estradiol on chimeric and wild type aldosterone synthase in vitro

Background: Obesity has been associated with reduced dexmedetomidine clearance, suggesting impaired hepatic function or reduced hepatic blood flow. The aim of this study was to clarify the effect of obesity in dexmedetomidine metabolic clearance. Methods: Forty patients, ASA IeIII, 18e60 yr old, ...


Rolle, Augusto.Paredes, S.Cortínez Fernández, Luis Ignacio.Quezada, Nicolás.Solari Gajardo, Sandra.Allende, Fidel.Torres Fuentes, Jorge Luis Alejandro.Cabrera García, Daniel Alejandro.Contreras Ibacache, Víctor.Carmona, J.[Dexmedetomidine metabolic clearance is not affected by fat mass in obese patients.]Dexmedetomidine metabolic clearance is not affected by fat mass in obese patients.

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