Previous studies using monoclonal antibody (mAb) 4C9 specific for a 32 kDa antigen (p32) of Theileria parva demonstrated expression of the antigen on the surface of the sporozoite, making it a potential antigen for sporozoite neutralization. A full-length cDNA encoding the major merozoite/piropla...
Skilton, Robert A.
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Musoke, A.J.
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Wells, C.W.
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Yagi, Y.
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Nene, Vishvanath
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Spooner, P.R.
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Gachanja, J.
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Osaso, J.
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Bishop, Richard P.
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Morzaria, S.P.
,
[A 32 kDa surface antigen of Theileria parva: Characterization and immunization studies]
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A 32 kDa surface antigen of Theileria parva: Characterization and immunization studies
Morzaria, S.P.
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Irvin, A.D.
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Taracha, E.A.
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Spooner, P.R.
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Voigt, W.P.
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Fujinaga, T.
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Katende, J.M.
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[Immunization against East Coast fever. The use of selected stocks of Theileria parva for immunization of cattle exposed to field challenge]
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Immunization against East Coast fever. The use of selected stocks of Theileria parva for immunization of cattle exposed to field challenge
Theileria parva schizont-infected lymphocyte culture isolates from western, central and coastal Kenya were analysed for size polymorphism at 30 T. parva-specific variable number tandem repeat (VNTR) loci using a panel of mini- and micro-satellite markers. The mean number of alleles ranged from 3 ...
Odongo, David O.
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Oura, C.A.
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Spooner, P.R.
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Kiara, Henry K.
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Mburu, D.
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Hanotte, Olivier H.
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Bishop, Richard P.
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[Linkage disequilibrium between alleles at highly polymorphic mini- and micro-satellite loci of Theileria parva isolated from cattle in three regions of Kenya]
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Linkage disequilibrium between alleles at highly polymorphic mini- and micro-satellite loci of Theileria parva isolated from cattle in three regions of Kenya
The current Infection and Treatment Method of vaccination against East Coast fever comprises an inoculation of live Theileria parva sporozoites and simultaneous administration of oxytetracycline. Immunization with a combination of parasite types has been shown to provide broader protection than i...
Patel, Ekta
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Lubembe, D.M.
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Gachanja, J.
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Mwaura, S.
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Spooner, P.R.
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Toye, Philip G.
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[Molecular characterization of live Theileria parva sporozoite vaccine stabilates reveals extensive genotypic diversity]
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Molecular characterization of live Theileria parva sporozoite vaccine stabilates reveals extensive genotypic diversity
Minami, T.
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Spooner, P.R.
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Irvin, A.D.
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Ocama, J.G.R.
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Dobbelaere, D.A.E.
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Fujinaga, T.
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[Characterisation of stocks of Theileria parva by monoclonal antibody profiles]
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Characterisation of stocks of Theileria parva by monoclonal antibody profiles
Protective immunity induced by the infective sporozoite stage of Theileria parva indicates a potential role for antibodies directed against conserved serologically reactive regions of the major sporozoite surface antigen p67 in vaccination to control the parasite. We have examined the allelic var...
Obara, I.
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Ulrike, S.
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Musoke, A.J.
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Spooner, P.R.
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Jabbar, A.
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Odongo, D.
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Kemp, Stephen J.
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Silva, J.C.
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Bishop, Richard P.
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[Molecular evolution of a central region containing B cell epitopes in the gene encoding the p67 sporozoite antigen within a field population of Theileria parva]
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Molecular evolution of a central region containing B cell epitopes in the gene encoding the p67 sporozoite antigen within a field population of Theileria parva