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GI nematodes are most commonly controlled by chemotherapy. Anthelmintic efficacy is decreasing as drug resistance becomes widespread and other approaches are needed. Knowledge of protective immunity against GI parasites is important for the development of vaccine strategies. Success in this field...


Behnke, J.M.Lowe, A.Menge, M.Iraqi, F.A.Wakelin, D.[Mapping genes for resistance to gastrointestinal nematodes]Mapping genes for resistance to gastrointestinal nematodes

A comparison of F2 and F6/7 inter-cross lines of mice, derived from CBA and SWR parental strains, has provided strong evidence for several previously undetected quantitative trait loci (QTL) for resistance to Heligmosomoides bakeri. Five QTL affecting average faecal egg counts and/or worm burdens...


Behnke, J.M.Menge, D.M.Nagda, S.M.Noyes, H.Iraqi, F.A.Kemp, Stephen J.Mugambi, R.J.M.Baker, R.L.Wakelin, D.Gibson, John P.[Quantitative trait loci for resistance to Heligmosomoides bakeri and associated immunological and pathological traits in mice: comparison of loci on chromosomes 5, 8 and 11 in F2 and F6/7 inter-cross lines of mice]Quantitative trait loci for resistance to Heligmosomoides bakeri and associated immunological and pathological traits in mice: comparison of loci on chromosomes 5, 8 and 11 in F2 and F6/7 inter-cross lines of mice

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