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Recent demonstration of an ability of human and murine dendritic cells (DC) to acquire exogenous antigens, present them as peptide complexes with MHC class I molecules and induce antigen specific CD8+ cytotoxic T lymphocyte (CTL) responses, a process termed cross-presentation, has led to a reasse...

Trypanosoma congolense, which is responsible for most of animal trypanosomiasis 10 Africa, has a great diversity of variants. Differences occur between stocks from different geographical regions and also between stocks within the same area. In the present work molecular karyotyping was used to in...

Casein kinase II from Trypanosoma congolense has been partially purified by chromatography on DEAE-cellulose and heparin-agarose and this subunit exhibits protein kinase activity with casein as the substrate. The enzyme adhered to both the DEAE-cellulose and heparin-agarose resins and was eluted ...

The Murang'a District is situated in central Kenya and is a highland area with a high potential for dairy production. This study was carried out to evaluate the performance of smallholder dairy farms by analysing available data and by simulation modelling. Eighteen case farms were selected non-ra...

This thesis describes a study of the epidemiology of theileriosis on smallholder dairy farms in Murang'a District situated in central highlands of Kenya. The main objectives were: 1) to characterise different areas within the district as to their risks for tick-borne diseases (TBDs), in particula...

The studies described in this thesis were conducted to evaluate field application of the antigen-detection tube Enzyme Linked Immunosorbent Assay (ELISA) kit developed by Nantulya (1989) for diagnosis of Trypanosoma evansi infections in camels. The study was carried out on a herd of 100 camels in...

Since the anaemia of T. congolense infection, which has been shown to be mainly due to erythrocyte destruction by macrophages of the mononuclear phagocytic system, has been shown to be associated with poor reticulocyte response, a study was designed to verify if the unresponsiveness is attributab...

Mammalian hosts of African trypanosomes show marked differences in susceptibility to infection with Trypanosoma congolense as judged by survival time, anaemia, and levels of parasitaemia. For instance, the N'Dama cattle and the West African shorthorn breeds are resistant to Trypanosomiasis wherea...

This study deals with the analysis of pricing efficiency and seasonal supply patterns for milk in Kenya. The analysis is based on data from secondary sources and discussions with the sample farmers on ' the milk marketing problems.' The performances of the Kenya Cooperative Creameries (KCC) and t...

Ecology of Glossina fuscipes fuscipes Newstead was studied with specific reference to temperature, relative humidity, light intensity, resting and breeding sites. The comprehensive study was undertaken to assemble, upgrade and bridge gaps in information on the species which would be used in organ...