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Molecular tools based on seminested RFLP-PCR techniques to characterize field parasites in bloodspots dried on filter paper permitted investigation of the extent and the dynamics of diversity of Theileria parva populaitons in the field. Parallel molecular studies explored the long-term genome sta...
The major sporozoite surface antigen of Theileria annulata (SPAG-1) is a candidate for inclusion in a subunit vaccine. In this paper we summarize the results of 4 vaccination experiments using recombinant SPAG-1 expressed in different systems and presented in different adjuvants. The antigen has ...
This paper determines whether contact between parasite-specific CD4+ T cells and CD8+ T cells is an essential requirement for helper function, additional experiments were performed using two-chamber culture plates incorporating semi-porous membranes. TpM were co-cultured with naive or immune CD8 ...
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