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Emery, D.L.Eugui, E.M.Nelson, R.T.Tenywa, T.[Cell-mediated immune responses to Theileria parva (East Coast fever) during immunization and lethal infections in cattle]Cell-mediated immune responses to Theileria parva (East Coast fever) during immunization and lethal infections in cattle

Previous data showed that six out of a group of nine cattle inoculated with NS1-p67, a recombinant form of a 67-KDa Theileria parva sporozoite surface protein, were immune to East Coast fever. This bacterialy expressed antigen encoded all 709 amino acid residues of p67 fused to the C-terminal end...


Nene, VishvanathInumaru, S.McKeever, Declan J.Morzaria, S.P.Shaw, M.Musoke, A.J.[Characterization of an insect cell-derived Theileria parva sporozoite vaccine antigen and immunogenicity in cattle]Characterization of an insect cell-derived Theileria parva sporozoite vaccine antigen and immunogenicity in cattle

Initial laboratory trials of an experimental subunit vaccine against Theileria parva based on the 67-kDa major sporozoite surface antigen revealed a range of responses to challenge. We have analyzed convergence in seven sets of monozygotic twins which suggests that genetic factors may have an i...


Ballingall, K.T.Luyai, A.Rowlands, G.J.Sales, J.Musoke, A.J.Morzaria, S.P.McKeever, Declan J.[Bovine leukocyte antigen major histocompatibility complex class II DRB3*2703 and DRB3*1501 alleles are associated with variation in levels of protection against Theileria parva challenge following immunization with the sporozoite p67 antigen]Bovine leukocyte antigen major histocompatibility complex class II DRB3*2703 and DRB3*1501 alleles are associated with variation in levels of protection against Theileria parva challenge following immunization with the sporozoite p67 antigen

Peripheral blood mononuclear cells (PBMC) from immune cattle proliferate in the presence of autologous Cowdria ruminantium-infected endothelial cells and monocytes. Endothelial cells required treatment with T-cell growth factors to induce class II major histocompatibility complex expression prior...


Mwangi, D.M.Mahan, S.M.Nyanjui, J.K.Taracha, E.L.N.McKeever, Declan J.[Immunization of cattle by infection with Cowdria ruminantium elicits T lymphocytes that recognize autologous, infected endothelial cells and monocytes]Immunization of cattle by infection with Cowdria ruminantium elicits T lymphocytes that recognize autologous, infected endothelial cells and monocytes
Emery, D.L.Morrison, W. IvanBuscher, G.Nelson, R.T.[Generation of cell-mediated cytotoxicity to Theileria parva (East Coast fever) after inoculation of cattle with parasitized lymphoblasts]Generation of cell-mediated cytotoxicity to Theileria parva (East Coast fever) after inoculation of cattle with parasitized lymphoblasts

International Laboratory for Research on Animal Diseases[ILRAD Reports. Volume 1. Number 1. July 1983]ILRAD Reports. Volume 1. Number 1. July 1983
Autor: Dolan, T.T.

The Tick-Borne Diseases Programme at the International Laboratory for Research on Animal Disease (ILRAD) has as its own major objective the improvement of the control of tick-borne diseases by immunological means. The focus of its research has been a novel vaccine for Theileria parva, the cause ...


Dolan, T.T.[The tick-borne diseases research programme at ILRAD]The tick-borne diseases research programme at ILRAD
Laker, C.D.Mukhebi, A.W.Ssenyonga, G.S.Z.Gathuma, J.M.Ssentongo, Y.K.Otim, C.P.[A financial analysis of East Coast fever immunization in Mbarara District, Uganda]A financial analysis of East Coast fever immunization in Mbarara District, Uganda

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