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East Coast fever (ECF) is a highly fatal lymphoproliferative disease of cattle caused by Theileria parva, a tick-borne intracellular apicomplexan parasite. Parasite antigens that are targets of protective cytotoxic T lymphocyte (CTL) responses are required to formulate a sub-unit vaccine against ...


Akoolo, L.Pelle, RogerSaya, R.Awino, EliasNyanjui, J.Taracha, E.L.N.Kanyari, P.Mwangi, D.M.Graham, S.P.[Evaluation of the recognition of Theileria parva vaccine candidate antigens by cytotoxic T lymphocytes from Zebu cattle]Evaluation of the recognition of Theileria parva vaccine candidate antigens by cytotoxic T lymphocytes from Zebu cattle

The ‘Muguga cocktail’ live vaccine, delivered by an infection and treatment protocol, has been widely deployed in Eastern, Central and Southern Africa to protect cattle against East Coast fever, caused by Theileria parva. The vaccine contains 3 component stocks (Muguga, Serengeti-transformed and ...


Oura, C.A.L.Bishop, Richard P.Asiimwe, B.B.Spooner, P.R.Lubega, G.W.Tait, A.[Theileria parva live vaccination: parasite transmission, persistence and heterologous challenge in the field]Theileria parva live vaccination: parasite transmission, persistence and heterologous challenge in the field
Dolan, T.T.Mutugi, J.J.M.[The fertility of Boran heifers immunized against buffalo-derived Theileria parva]The fertility of Boran heifers immunized against buffalo-derived Theileria parva

International Laboratory for Research on Animal Diseases[Experiments with twin calves offer evidence that cytotoxic T cells can clear T. parva infections]Experiments with twin calves offer evidence that cytotoxic T cells can clear T. parva infections

Immunity against the bovine intracellular protozoan parasite Theileria parva has been shown to be mediated through the destruction of parasite infected lymphocytes by MHC class I restricted CD8+ CTL. Six parasite proteins targeted by CTL from T. parva immune cattle have been identified and raised...


Graham, S.P.Pelle, RogerVilliers, Etienne P. deYamage, M.Mwangi, D.M.Honda, Y.Ellis, S.A.MacHugh, Niall D.Morrison, W. IvanTaracha, E.L.N.[Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva]Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva
Moulton, J.Buscher, G.Bovell, D.L.Doxsey, S.[Blast transformation of adherent macrophages infected in vitro with sporozoites of Theileria parva]Blast transformation of adherent macrophages infected in vitro with sporozoites of Theileria parva
Pearson, T.W.Anderson, L.[Analytical techniques for cell fractions. 28. Dissection of complex antigenic mixtures using monoclonal antibodies and two-dimensional gel electrophoresis]Analytical techniques for cell fractions. 28. Dissection of complex antigenic mixtures using monoclonal antibodies and two-dimensional gel electrophoresis
Goddeeris, B.M.Morrison, W. Ivan[Techniques for the generation, cloning and characterisation of bovine cytotoxic T cells specific for the protozoan Theileria parva]Techniques for the generation, cloning and characterisation of bovine cytotoxic T cells specific for the protozoan Theileria parva
Morzaria, S.P.Musoke, A.J.Latif, A.A.[Recognition of Theileria parva antigens by field sera from Rusinga Island Kenya]Recognition of Theileria parva antigens by field sera from Rusinga Island Kenya

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