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Background The PLATINO project was launched in 2002 in order to study the prevalence of chronic obstructive pulmonary disease (COPD) in Latin America. Because smoking is the main risk factor for COPD, detailed data on it were obtained. The aim of this paper was to evaluate the prevalence of smoki...


Menezes, Ana M.López, Maria V.Hallal, Pedro C.Muiño, Adriana.Pérez Padilla, Rogelio.Jardim, José R.Valdivia Cabrera, Gonzalo.Pertuzé, Julio, 1948-De Oca, Maria M.Tálamo, Carlos.Victora, Cesar G.[Prevalence of smoking and incidence of initiation in the latin american adult population: the PLATINO study]Prevalence of smoking and incidence of initiation in the latin american adult population: the PLATINO study

Varas Orozco, Rodrigo.Iturriaga, Rodrigo Doctor en Ciencias BiológicasAlcayaga, C.Cerpa, V.Alcayaga, J.[Ionic currents and action potential induced by electrical stimulation, ACh and ATP in petrosal ganglion neurons]Ionic currents and action potential induced by electrical stimulation, ACh and ATP in petrosal ganglion neurons

Abstract Background Gastric contents aspiration in humans is a risk factor for severe respiratory failure with elevated mortality. Although aspiration-induced local lung inflammation has been studied in animal models, little is known about extrapulmo...


Ayala, PedroMeneses, ManuelOlmos, PabloMontalva, RebecaDroguett Quezada, Karla Denise.Rios Raggio, Mariana.Borzone, Gisella R.[Acute lung injury induced by whole gastric fluid: hepatic acute phase response contributes to increase lung antiprotease protection]Acute lung injury induced by whole gastric fluid: hepatic acute phase response contributes to increase lung antiprotease protection

Abstract Background Although high-intensity non-invasive ventilation has been shown to improve outcomes in stable COPD, it may adversely affect cardiac performance. Therefore, the aims of the present pilot study were to compare cardiac and pulmonary ...


Duiverman, Marieke L.Arellano Maric, Maria Paola.Maagh, Petra.Magnet, Friederike S.Schmoor, Claudia.Meissner, Axel.Storre, Jan H.Wijkstra, Peter J.Windisch, Wolfram.Callegari, Jens.[Impact of High-Intensity-NIV on the heart in stable COPD: a randomised cross-over pilot study]Impact of High-Intensity-NIV on the heart in stable COPD: a randomised cross-over pilot study

Abstract Background Gastric contents aspiration is a high-risk condition for acute lung injury (ALI). Consequences range from subclinical pneumonitis to respiratory failure, depending on the volume of aspirate. A large increment in inflammatory cells...


Ayala, Pedro.Vivar, Raúl.Montalva, Rebeca.Olmos Coelho, Pablo Roberto.Borzone, Gisella.Meneses, Manuel.[Elastin degradation products in acute lung injury induced by gastric contents aspiration]Elastin degradation products in acute lung injury induced by gastric contents aspiration

Abstract Background Gastric contents aspiration in humans has variable consequences depending on the volume of aspirate, ranging from subclinical pneumonitis to respiratory failure with up to 70% mortality. Several experimental approaches have been u...


Ayala, PedroTorres, JorgeVivar, RaúlMeneses, ManuelOlmos, PabloSan Martín, TamaraBorzone, Gisella R.[Acute lung injury by gastric fluid instillation: activation of myofibroblast apoptosis during injury resolution]Acute lung injury by gastric fluid instillation: activation of myofibroblast apoptosis during injury resolution

Abstract Background Exposure to noxious gases and particles contained in both tobacco smoking (TS) and biomass smoke (BS) are well recognized environmental risk factors for chronic obstructive pulmonary disease (COPD). COPD is characterized by an abn...


Valdivia Cabrera, Gonzalo.Olloquequi, Jordi.Jaime, Sergio.Parra, Viviana.Cornejo-Córdova, Elizabeth.Agustí, Àlvar.Silva O., Rafael.[Comparative analysis of COPD associated with tobacco smoking, biomass smoke exposure or both]Comparative analysis of COPD associated with tobacco smoking, biomass smoke exposure or both

Abstract Background A focus on equity in health can be seen in many global development goals and reports, research and international declarations. With the development of a relevant framework and methods, the Campbell and Cochrane Equity Methods Grou...


Tugwell, Peter.Petkovic, Jennifer.Welch, Vivian.Vincent, Jennifer.Bhutta, Zulfiqar A.Churchill, Rachel.De Savigny, Don.Mbuagbaw, Lawrence.Pantoja, Tomas.[Setting priorities for knowledge translation of Cochrane reviews for health equity: evidence for equity]Setting priorities for knowledge translation of Cochrane reviews for health equity: evidence for equity

Hernández P., GlennLara, Bárbara.Enberg, L.Ortega, M.Leon, P.Kripper, Cristóbal.Aguilera, P.Kattan, E.Bakker, Jan.[ESICM LIVES 2016: part one]ESICM LIVES 2016: part one

Objective. To investigate the effect of collagen cross-links on the stability of adhesive properties, the degree of conversion within the hybrid layer, cytotoxicity and the inhibition potential of the MMPs' activity. Methods. The dentin surfaces of human molars were acid-etched and treated with p...


Hass, V.Luque-Martinez, I. V.Gutierrez, M. F.Moreira, C. G.Gotti, V. B.Feitosa, V. P.Koller, G.Otuki, M. F.Loguercio, A. D.Reis, A.[Collagen cross-linkers on dentin bonding: Stability of the adhesive interfaces, degree of conversion of the adhesive, cytotoxicity and in situ MMP inhibition]Collagen cross-linkers on dentin bonding: Stability of the adhesive interfaces, degree of conversion of the adhesive, cytotoxicity and in situ MMP inhibition

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