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Jara, J. A.López Muñoz, R.[Metformin and cancer: Between the bioenergetic disturbances and the antifolate activity]

Alibhai, Shabbir M. H.Breunis, HenrietteTimilshina, NarhariBrignardello Petersen, RominaTomlinson, GeorgeMohamedali, HassanabbasGupta, VikasMinden, Mark D.Li, MadelineBuckstein, RenaBrandwein, Joseph M.[Quality of life and physical function in adults treated with intensive chemotherapy for acute myeloid leukemia improve over time independent of age]

Expression of the scaffolding protein Caveolin-1 (CAV1) enhances migration and invasion of metastatic cancer cells. Yet, CAV1 also functions as a tumor suppressor in early stages of cancer, where expression is suppressed by epigenetic mechanisms. Thus, we sought to identify stimuli/mechanisms tha...


Díaz-Valdivia, N.I.Calderón, C.C.Díaz, J.E.Lobos-González, L.Sepulveda, H.Ortíz, R.J.Martinez, S.Silva, V.Maldonado, H.J.Silva, P.Wehinger, S.Burzio, V.A.Torres, V.A.Montecino, M.Leyton, L.Quest, A.F.G.[Anti-neoplastic drugs increase caveolin-1-dependent migration, invasion and metastasis of cancer cells]Anti-neoplastic drugs increase caveolin-1-dependent migration, invasion and metastasis of cancer cells

Background: Less than 10% of osteosarcomas are located the head and neck region, mainly affecting the mandible and maxillary region. Aim: To analyze the therapeutic modality, types of reconstruction, surgical complications and survival of patients treated for osteosarcoma of the head and neck. Ma...


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