During its first two years, the African trypanosome genome project, funded in part by the UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR), has concentrated on three fundamental areas: (1) gene discovery by single-pass sequencing of cDNAs to produce expre...
Melville, S.E.
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Majiwa, P.A.O.
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Donelson, J.E.
,
[Resources available from the African Trypanosome Genome Project]
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Resources available from the African Trypanosome Genome Project
This paper is a review of the meeting "Sleeping Sickness Rediscovered". The meeting focussed on human sleeping sickness, which, despite improvements in diagnosis and control has returned with a vengeance across central Africa. Topics of discussion include control activities; control tools; resear...
The use of geographical information systems (GIS) in the management of African animal trypanosomosis in sub-Saharan Africa offers potential in assisting decisions on allocation of resources, prioritization of control areas, and planning and management of field operations. Here, Guy Hendrickx and ...
Hendrickx, G.
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Rocque, S. de la
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Reid, Robin S.
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Wint, W.
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[Spatial trypanosomosis management: From data - layers to decision making]
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Spatial trypanosomosis management: From data - layers to decision making
The pathogenic trypanosomes Trypanosoma vivax and Trypanosoma congolense are transmitted by tsetse and cause trypanosomosis, a debilitating disease affecting livestock in Africa and South America. Here, we discuss the need, relevance and advantage of having the Trypanosoma genomes sequenced, an...
Davila, A.M.R.
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Majiwa, P.A.O.
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Grisard, E.C.
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Aksoy, S.
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Melville, S.E.
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[Comparative genomics to uncover the secrets of tsetse and livestock-infective trypanosomes]
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Comparative genomics to uncover the secrets of tsetse and livestock-infective trypanosomes
Investigations to identify the causes of high mortalities in cattle in the agropastoral zone (ZAP( of Yale started in March 1993. African animal trypanosomosis (AAT) was found to be the major constraint, with incidence rates exceeding 30 percent, justifying a tsetse control programme, which start...
Bauer, B.
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Amsler-Delafosse, S.
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Kabore, I.
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Kamuanga, M.
,
[Improvement of cattle productivity through rapid alleviation of African animal trypanosomiasis by integrated disease management practices in the agropastoral zone of Yale, Burkina Faso]
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Improvement of cattle productivity through rapid alleviation of African animal trypanosomiasis by integrated disease management practices in the agropastoral zone of Yale, Burkina Faso
A tsetse control campaign was started in January 1991 using a synthetic pyrethroid cypermethrin `pour-on' applied monthly to cattle exposed to high levels of drug-resistant trypanosomes in the Ghibe valley of southwest Ethiopia. In December 1992, a cost-recovery scheme was introduced, and thereaf...
Rowlands, G.J.
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Mulatu, W.
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Leak, S.G.A.
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Nagda, S.M.
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D'Ieteren, G.D.M.
,
[Estimating the effects of tsetse control on livestock productivity - a case study in southwest Ethiopia]
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Estimating the effects of tsetse control on livestock productivity - a case study in southwest Ethiopia
Few studies of land-use/land-cover change provide an integrated assessment of the driving forces and consequences of that change, particularly in Africa. Our objectives were to determine how driving forces at different scales change over time, how these forces affect the dynamics and patterns of ...
Reid, Robin S.
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Kruska, R.L.
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Muthui, N.
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Taye, A.
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Wotton, S.
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Wilson, C.J.
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Mulatu, W.
,
[Land-use and land-cover dynamics in response to changes in climatic, biological and socio-political forces: The case of southwestern Ethiopia]
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Land-use and land-cover dynamics in response to changes in climatic, biological and socio-political forces: The case of southwestern Ethiopia
This study illustrates how productivity impacts resulting from livestock research can be measured using a herd simulation model, how the results of this model can be extended spatially using geographic information systems (GIS) to determine the potential increase in livestock production that woul...
Kristjanson, Patricia M.
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Rowlands, G.J.
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Swallow, B.M.
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Kruska, R.L.
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Leeuw, P.N. de
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Nagda, S.M.
,
[Using the economic surplus model to measure potential returns to international livestock research. The case of trypanosomosis vaccine research]
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Using the economic surplus model to measure potential returns to international livestock research. The case of trypanosomosis vaccine research
The TNF-alfa gene on mouse chromosome MMU17 is among the candidates for the trypanosomosis resistance QTG Tirl. Tit t has the largest effect of those loci so far detected which influence degree of resistance to murine trypanosomosis caused by Trypanosome congolense infection. We therefore studied...