Descubre y comparte nuestro conocimiento público

Se han encontrado 62 recursos

Resultados de búsqueda

Shapiro, S.Z.[Failure of immunization with trypanosome endocytotic vesicle membrane proteins to provide nonvariant immunoprotection against Trypanosoma brucei]Failure of immunization with trypanosome endocytotic vesicle membrane proteins to provide nonvariant immunoprotection against Trypanosoma brucei

A whole farm simulation approach was used to assess the economic impacts of five alternative strategies for controlling East Coast fever (ECF), a cattle disease, on farms from two sites in Kenya. The strategies were also ranked using the stochastic dominance criterion to determine the most prefer...


Nyangito, H.O.Richardson, J.W.Mukhebi, A.W.Zimmel, P.Namken, J.Perry, Brian D.[Whole farm simulation analysis of economic impacts of East Coast fever immunization strategies on mixed crop-livestock farms in Kenya]Whole farm simulation analysis of economic impacts of East Coast fever immunization strategies on mixed crop-livestock farms in Kenya
Rovis, L.Musoke, A.J.Moloo, S.K.[Immunization trials against trypanosomiasis using common antigens]Immunization trials against trypanosomiasis using common antigens

Theileria annulata and Theileria parva both poses a major surface antigen on the sporozoite stage of the life-cycle, called SPAG-1 and p67, respectively. In each case, these antigens are vaccine candidates and have been shown to induce a degree of homologous protection in earlier work. These anti...


Hall, R.Boulter, N.R.Brown, C.G.D.Wilkie, G.Kirvar, E.Nene, VishvanathMusoke, A.J.Glass, E.J.Morzaria, S.P.[Reciprocal cross-protection induced by sporozoite antigens SPAG-1 from Theileria annulata and p67 from Theileria parva]Reciprocal cross-protection induced by sporozoite antigens SPAG-1 from Theileria annulata and p67 from Theileria parva

Two distinct genes encoding single domain, ATP-binding cassette transport protein homologues of Theileria parva were cloned and sequenced. Neither of the genes is tandemly duplicated. One gene, TpABCI, encodes a predicted protein of 593 amino acids with an N-terminal hydrophobic domain containing...


Kibe, M.K.Macklin, M.D.Gobright, E.I.Bishop, Richard P.Urakawa, T.Ole-MoiYoi, O.K.[Characterisation of single domain ATP-binding cassette protein homologues of Theileria parva]Characterisation of single domain ATP-binding cassette protein homologues of Theileria parva

A first-gneration subunit vaccine for East Coast fever based on the Theileria parva p67 sporozoite surface antigen is entering preliminary field trials. Intensive efforts are also focused on the identification of a schizont-specific omponen for incorporation in a second-generation multi-component...


McKeever, Declan J.Morrison, W. Ivan[Invited review Novel vaccines against Theileria parva: prospects for sustainability]Invited review Novel vaccines against Theileria parva: prospects for sustainability

Full-length recombinant versions of p67, the 709 amino acid major surface protein of Theileria parva sporozoites, induce immunity to East Coast fever (ECF) in cattle. We show that a soluble Escherichia coli recombinant version of p67 (p67635), in which a prokaryotic signal peptide replaces the e...


Bishop, Richard P.Nene, VishvanathStaeyert, J.Rowlands, G.J.Nyanjui, J.Osaso, J.Morzaria, S.P.Musoke, A.J.[Immunity to East Coast fever in cattle induced by a polypeptide fragment of the major surface coat protein of Theileria parva sporozoites]Immunity to East Coast fever in cattle induced by a polypeptide fragment of the major surface coat protein of Theileria parva sporozoites

Two recombinant vaccines against Theileria parva, based on a near full-length version of the sporozoite surface antigen p67 (p67635), or an 80 amino acid C-terminal section (p67C), were evaluated by exposure of immunized cattle to natural tick challenge in two sites at the Kenya Coast and one i...


Musoke, A.J.Rowlands, G.J.Nene, VishvanathNyanjui, J.Katende, J.Spooner, P.R.Mwaura, S.Odongo, D.Nkonge, C.Mbogo, S.Bishop, Richard P.Morzaria, S.P.[Subunit vaccine based on the p67 major surface protein of Theileria parva sporozoites reduces severity of infection derived from field tick challenge]Subunit vaccine based on the p67 major surface protein of Theileria parva sporozoites reduces severity of infection derived from field tick challenge

A clinical trial, comparing East Coast fever (ECF) control strategies in 5 different groups of traditionally managed Sanga cattle (44-49 animals per herd), was conducted in Zambia over 2.5 years between 1992 and 1995. Two groups were kept under intensive tick control by weekly cypermethrin (Barri...


Minjauw, B.Otte, M.J.James, A.D.Castro, J.J. deSinyangwe, P.[Effect of different East Coast Fever control strategies on disease incidence in traditionally managed Sanga cattle in Central Province of Zambia]Effect of different East Coast Fever control strategies on disease incidence in traditionally managed Sanga cattle in Central Province of Zambia
Tetley, L.Vickerman, K.Moloo, S.K.[Absence of a surface coat from metacyclic Trypanosoma vivax. Possible implications for vaccination against vivax trypanosomiasis]Absence of a surface coat from metacyclic Trypanosoma vivax. Possible implications for vaccination against vivax trypanosomiasis

Selecciona los documentos para visualizarlos

Nombre del archivo Ver recurso