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Journal Article 1999

Autor: Park, S.D.E. Adomefa, K. Dao, B. Hanotte, Olivier H. Kemp, Stephen J. Sow, R.S. Teale, A.J. Bradley, D.G.

We have sought to test the possibility of detecting regions of the genome under selection through effects on variation at linked neutral genetic markers. Particularly, we investigated three genomic regions identified by mapping in a cross-bred pedigree as harbouring QTL for trypanosomiasis tolera...

Enlace original: https://cgspace.cgiar.org/handle/10568/28361

Investigación en Agricultura
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Park, S.D.E. ,  Adomefa, K. ,  Dao, B. ,  Hanotte, Olivier H. ,  Kemp, Stephen J. ,  Sow, R.S. ,  Teale, A.J. ,  Bradley, D.G. ,  [Application of population genetic analysis of linked, mapped microsatellites to the identification of loci under selection for disease resistance] ,  Application of population genetic analysis of linked, mapped microsatellites to the identification of loci under selection for disease resistance
Journal Article 2003

Autor: Naessens, Jan Leak, S.G.A. Kennedy, D.J. Kemp, Stephen J. Teale, A.J.

West African N'Dama cattle have developed a genetic capacity to survive, reproduce and remain productive under trypanosomosis risk. The cellular and molecular bases of this so-called trypanotolerance are not known, but the trait is manifested by the N'Dama's greater capacity to control parasitae...

Enlace original: https://cgspace.cgiar.org/handle/10568/33227

Investigación en Agricultura
Enlace permanente
Naessens, Jan ,  Leak, S.G.A. ,  Kennedy, D.J. ,  Kemp, Stephen J. ,  Teale, A.J. ,  [Responses of bovine chimaeras combining trypanosomosis resistant and susceptible genotypes to experimental infection with Trypanosoma congolense] ,  Responses of bovine chimaeras combining trypanosomosis resistant and susceptible genotypes to experimental infection with Trypanosoma congolense
Journal Article 2003

Autor: Naessens, Jan Mwangi, D.M. Buza, J. Moloo, S.K.

The first visible response in livestock to the bite of a trypanosome-infected tsetse fly is the formation of a localized skin reaction, also known as a chancre. This is an inflammatory response in the skin associated with swelling and an influx of cells. It is thought to be associated with an a...

Enlace original: https://cgspace.cgiar.org/handle/10568/33088

Investigación en Agricultura
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Naessens, Jan ,  Mwangi, D.M. ,  Buza, J. ,  Moloo, S.K. ,  [Local skin reaction (chancre) induced following inoculation of metacyclic trypanosomes in cattle by tsetse flies is dependent on CD4 T lymphocytes] ,  Local skin reaction (chancre) induced following inoculation of metacyclic trypanosomes in cattle by tsetse flies is dependent on CD4 T lymphocytes
Journal Article 2005-01-28

Autor: Naessens, Jan Kitani, H. Nakamura, Y. Yagi, Y. Sekikawa, K. Iraqi, F.A.

Development of anaemia in inflammatory diseases is cytokine-mediated. Specifically, the levels of tumour necrosis factor-α (TNF-α), produced by activated macrophages, are correlated with severity of disease and anaemia in infections and chronic disease. In African trypanosomiasis, anaemia develop...

Enlace original: https://cgspace.cgiar.org/handle/10568/1434

Investigación en Agricultura
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Naessens, Jan ,  Kitani, H. ,  Nakamura, Y. ,  Yagi, Y. ,  Sekikawa, K. ,  Iraqi, F.A. ,  [TNF-a mediates the development of anaemia in a murine Trypanosoma brucei rhodesiense infection, but not the anaemia associated with a murine Trypanosoma congolense infection] ,  TNF-a mediates the development of anaemia in a murine Trypanosoma brucei rhodesiense infection, but not the anaemia associated with a murine Trypanosoma congolense infection
Journal Article 2005

Autor: Naessens, Jan Kitani, H. Nakamura, Y. Yagi, Y. Sekikawa, K. Iraqi, F.A.

Development of anaemia in inflammatory diseases is cytokine-mediated. Specifically, the levels of tumour necrosis factor-alpha (TNF-alpha), produced by activated macrophages, are correlated with severity of disease and anaemia in infections and chronic disease. In African trypanosomiasis, anaemia...

Enlace original: https://cgspace.cgiar.org/handle/10568/32870

Investigación en Agricultura
Enlace permanente
Naessens, Jan ,  Kitani, H. ,  Nakamura, Y. ,  Yagi, Y. ,  Sekikawa, K. ,  Iraqi, F.A. ,  [TNF-alpha mediates the development of anaemia in a murine Trypanosoma brucei rhodesiense infection, but not the anaemia associated with a murine Trypanosoma congolense infection] ,  TNF-alpha mediates the development of anaemia in a murine Trypanosoma brucei rhodesiense infection, but not the anaemia associated with a murine Trypanosoma congolense infection
Journal Article 2002

Autor: Naessens, Jan Teale, A.J. Sileghem, M.R.

Natural resistance to African trypanosomiasis in certain Bos taurus cattle in West Africa, called trypanotolerance, may hold solutions for control of this economically crippling disease. Comparison of immune responses between trypanotolerant and trypanosusceptible cattle have shown some differen...

Enlace original: https://cgspace.cgiar.org/handle/10568/33225

Investigación en Agricultura
Enlace permanente
Naessens, Jan ,  Teale, A.J. ,  Sileghem, M.R. ,  [Identification of mechanisms of natural resistance to African trypanosomiasis in cattle] ,  Identification of mechanisms of natural resistance to African trypanosomiasis in cattle
Journal Article 2019-11-14

Autor: Ayalew, Y. Gültas, M. Effa, K. Hanotte, Olivier H. Schmitt, A.O.
Enlace original: https://cgspace.cgiar.org/handle/10568/106328

Investigación en Agricultura
Enlace permanente
Ayalew, Y. ,  Gültas, M. ,  Effa, K. ,  Hanotte, Olivier H. ,  Schmitt, A.O. ,  [Identification of candidate signature genes and key regulators associated with Trypanotolerance in the Sheko Breed] ,  Identification of candidate signature genes and key regulators associated with Trypanotolerance in the Sheko Breed
Journal Article 2003

Autor: Omamo, S.W. D'Ieteren, G.D.M.

This paper discusses past and present approaches to managing tsetse-transmitted animal trypanosomosis in Africa and describes the three main weaknesses of these approaches, i.e., inappropriate objectives, inadequate links between research and policy-making and a lack of recognition that trypano...

Enlace original: https://cgspace.cgiar.org/handle/10568/29314

Investigación en Agricultura
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Omamo, S.W. ,  D'Ieteren, G.D.M. ,  [Managing animal trypanosomosis in Africa: Issues and options] ,  Managing animal trypanosomosis in Africa: Issues and options
Journal Article 1989

Autor: Nantulya, V.M.
Enlace original: https://cgspace.cgiar.org/handle/10568/29352

Investigación en Agricultura
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Nantulya, V.M. ,  [An antigen detection enzyme immunoassay for the diagnosis of Rhodesiense sleeping sickness] ,  An antigen detection enzyme immunoassay for the diagnosis of Rhodesiense sleeping sickness

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