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Article 2018

Autor: Díaz-García, V.M. Guerrero, S. Díaz-Valdivia, N. Lobos-González, L. Kogan, M. Pérez-Donoso, J.M. Quest, A.F.G.

Background: Numerous studies have proposed the use of fluorescent semiconductor nanoparticles or quantum dots (QDs) as novel tools to label cells and tumors. However, QD applications are limited by their toxicity in biological systems and little is known about whether QDs affect the capacity of c...

Enlace original: http://repositorio.unab.cl/xmlui/handle/ria/11518

Repositorio Universidad Andrés Bello
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Díaz-García, V.M. ,  Guerrero, S. ,  Díaz-Valdivia, N. ,  Lobos-González, L. ,  Kogan, M. ,  Pérez-Donoso, J.M. ,  Quest, A.F.G. ,  [Biomimetic quantum dot-labeled B16F10 murine melanoma cells as a tool to monitor early steps of lung metastasis by in vivo imaging] ,  Biomimetic quantum dot-labeled B16F10 murine melanoma cells as a tool to monitor early steps of lung metastasis by in vivo imaging
Article 2018-10

Autor: Armando, R.G. Gómez, D.L.M. Juritz, E.I. Menna, P.L. Gomez, D.E.

Immortality is one of the main features of cancer cells. Tumor cells have an unlimited replicative potential, principally due to the holoenzyme telomerase. Telomerase is composed mainly by dyskerin (DKC1), a catalytic retrotranscriptase (hTERT) and an RNA template (hTR). The aim of this work is t...

Enlace original: http://repositorio.unab.cl/xmlui/handle/ria/11376

Repositorio Universidad Andrés Bello
hTR
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Armando, R.G. ,  Gómez, D.L.M. ,  Juritz, E.I. ,  Menna, P.L. ,  Gomez, D.E. ,  [Homology model and docking-based virtual screening for ligands of human dyskerin as new inhibitors of telomerase for cancer treatment] ,  Homology model and docking-based virtual screening for ligands of human dyskerin as new inhibitors of telomerase for cancer treatment
Article 2019

Hypercoagulable state is linked to cancer progression; however, the precise role of the coagulation cascade is poorly described. Herein, we examined the contribution of a hypercoagulative state through the administration of intravenous Coagulation Factor Xa (FXa), on the growth of solid human tum...

Enlace original: https://repositorio.udd.cl/handle/11447/3186

Repositorio Institucional Universidad del Desarrollo
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Article 2019

The family of long noncoding mitochondrial RNAs (ncmtRNAs), comprising sense (SncmtRNA), and antisense (ASncmtRNA-1 and ASncmtRNA-2) members, are differentially expressed according to cell proliferative status; SncmtRNA is expressed in all proliferating cells, while ASncmtRNAs are expressed in no...

Enlace original: https://repositorio.udd.cl/handle/11447/2868

Repositorio Institucional Universidad del Desarrollo
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Article 2018

Background: Numerous studies have proposed the use of fluorescent semiconductor nanoparticles or quantum dots (QDs) as novel tools to label cells and tumors. However, QD applications are limited by their toxicity in biological systems and little is known about whether QDs affect the capacity of c...

Enlace original: https://repositorio.udd.cl/handle/11447/2869

Repositorio Institucional Universidad del Desarrollo
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Article 2020

Aims: Breast cancer is one of the leading causes of woman deaths worldwide, being a major public health problem. It has been reported that the expression of the RNA-editing enzyme Adenosine Deaminase Acting on RNAs 1 (ADAR1) is upregulated in breast cancer, predicting poor prognosis in patients. ...

Enlace original: https://repositorio.udd.cl/handle/11447/3724

Repositorio Institucional Universidad del Desarrollo
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Article 2019

Background: Epanorin (EP) is a secondary metabolite of the Acarospora lichenic species. EP has been found in lichenic extracts with antimicrobial activity, and UV-absorption properties have been described for closely related molecules; however, its antiproliferative activity in cancer cells has n...

Enlace original: https://repositorio.udd.cl/handle/11447/3130

Repositorio Institucional Universidad del Desarrollo
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Article 2018

Recessive dystrophic epidermolysis bullosa (RDEB) is a rare inherited skin and mucous membrane fragility disorder complicated by early-onset, highly malignant cutaneous squamous cell carcinomas (SCCs). The molecular etiology of RDEB SCC, which arises at sites of sustained tissue damage, is unknow...

Enlace original: https://repositorio.udd.cl/handle/11447/2509

Repositorio Institucional Universidad del Desarrollo
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Article 2019

Tumor cells can interact with neighboring adipose tissue. We evaluated components present in human adipose explants from normal (hRAN) and kidney cancer (hRAT) tissue, and we evaluated the effects of conditioned media (CMs) from hRAN and hRAT on proliferation, adhesion and migration of tumor and ...

Enlace original: https://repositorio.udd.cl/handle/11447/3068

Repositorio Institucional Universidad del Desarrollo
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