Se denomina Mímica Vasculogénica (Vasculogenic Mimicry, VM) al proceso de formación de estructuras tubulares interconectadas, capaces de conducir fluido, por células no-endoteliales. Su presencia en biopsias tumorales ha sido asociada a una menor sobrevida general para los pacientes afectados. A ...
Vasculogenic mimicry (VM) describes a process by which cancer cells establish an alternative perfusion pathway in an endothelial cell-free manner. Despite its strong correlation with reduced patient survival, controversy still surrounds the existence of an in vitro model of VM. Furthermore, many ...
Light at night is essential to a 24/7 society, but it has negative consequences on health. Basically, light at night induces an alteration of our biological clocks, known as chronodisruption with effects even when this occurs during pregnancy. Indeed, an abnormal photoperiod during gestation alte...
Aumentos de Angiotensina II (AngII) plasmática causan Hipertensión Arterial (HTA), inflamación y daño de tejidos blanco. Estudios recientes indican que el sistema inmune participa en la generación del aumento de presión arterial (PA) en respuesta AngII. El suministro de fármacos inmunosupresores ...
High Angiotensin II (AngII) plasma levels cause Hypertension (HBP), inflammation and target tissues damage. Recent studies indicate that the immune system participates in the generation of increased blood pressure (BP) in response to AngII. The administration of immunosuppressive drugs that decre...
Trypanosoma cruzi (T. cruzi) es el agente causal de la enfermedad de Chagas. El parásito invade principalmente al tejido cardíaco, provocando miocarditis aguda y arritmias. Durante la invasión, El contacto del parásito con la célula huésped induce la liberación de ATP y transientes de Ca2+ intra...
Trypanosoma cruzi (T. cruzi) is the causative agent of Chagas disease. The parasite invades mainly cardiac tissue, causing acute myocarditis and arrhythmias. During the invasión, The contact of the parasite with the host cell induces ATP release and intracellular Ca2+ transients. However, the cel...
