Cabrera, D.
,
Cabello-Verrugio, C.
,
Solís, N.
,
Martín, D.S.
,
Cofré, C.
,
Pizarro, M.
,
Arab, J.P.
,
Abrigo, J.
,
Campos, F.
,
Irigoyen, B.
,
Carrasco-Avino, G.
,
Bezares, K.
,
Riquelme, V.
,
Riquelme, A.
,
Arrese, M.
,
Barrera, F.
,
[Somatotropic axis dysfunction in non-alcoholic fatty liver disease: Beneficial hepatic and systemic effects of hormone supplementation]
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Somatotropic axis dysfunction in non-alcoholic fatty liver disease: Beneficial hepatic and systemic effects of hormone supplementation
Immobilization is a form of disuse characterized by a loss of strength and muscle mass. Among the main features are decreased IGF-1/Akt signalling and increased ubiquitin-proteasome pathway signalling, which induce greater myosin heavy chain degradation. Activation of the classical renin-angioten...
Morales, M.G.
,
Abrigo, J.
,
Acuna, M.J.
,
Santos, R.A.
,
Bader, M.
,
Brandan, E.
,
Simon, F.
,
Olguin, H.
,
Cabrera, D.
,
Cabello-Verrugio, C.
,
[Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas]
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Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas
Angiotensin (1–7) (Ang-(1–7)) is a bioactive heptapeptide with a short half-life and has beneficial effects in several tissues – among them, skeletal muscle – by preventing muscle atrophy. Dendrimers are promising vehicles for the protection and transport of numerous bioactive molecules. This wor...
Márquez-Miranda, V.
,
Abrigo, J.
,
Rivera, J.C.
,
Araya-Durán, I.
,
Aravena, J.
,
Simon, F.
,
Pacheco, N.
,
González-Nilo, F.D.
,
Cabello-Verrugio, C.
,
[The complex of PAMAM-OH dendrimer with Angiotensin (1–7) prevented the disuse-induced skeletal muscle atrophy in mice]
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The complex of PAMAM-OH dendrimer with Angiotensin (1–7) prevented the disuse-induced skeletal muscle atrophy in mice