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Agaba, MorrisKemp, Stephen J.[Characterization of the 3' untranslated region of bovine parathyroid hormone gene in N'Dama and Boran cattle]Characterization of the 3' untranslated region of bovine parathyroid hormone gene in N'Dama and Boran cattle

Thymic-derived lymphocytes (T cells) recognize and respond to antigens through the mediation of the T-cell receptor complex. Here we report polymorphism at each of the five loci that encode the different components of the T-cell receptor complex in cattle. These genes were mapped on the bovine ge...


Agaba, MorrisKemp, Stephen J.Barendse, W.Teale, A.J.[Genetic mapping of bovine T-cell receptor complex loci]Genetic mapping of bovine T-cell receptor complex loci

High-through put technologies inevitably produce vast quantities of data. This presents challenges in terms of developing effective analysis methods, particularly where the analysis involves combining data derived from different experimental technologies. In this investigation, a systematic appro...


Rennie, C.Hulme, H.Fisher, P.Halp, L.Agaba, MorrisNoyes, H.A.Kemp, Stephen J.Brass, A.[A systematic, data-driven approach to the combined analysis of microarray and QTL data]A systematic, data-driven approach to the combined analysis of microarray and QTL data

It is known that different breeds of cattle display differential susceptibilities to Trypanosome congolense infections, and that N'Dama cattle remain more productive after infection than Boran cattle which are more susceptible to T. congolense. Macrophages from both breeds were cultured in vitro ...


Kazuhiro, Y.Agaba, MorrisIraqi, F.A.Naessens, Jan[Cytokine mRNA profiles in bovine macrophages stimulated with Trypanosoma congolense]Cytokine mRNA profiles in bovine macrophages stimulated with Trypanosoma congolense

Trypanosomosis, or sleeping sickness, is a major disease constraint on livestock productivity in sub-Saharan Africa. To identify quantitative trait loci (QTL) controlling resistance to trypanosomosis in cattle, an experimental cross was made between trypanotolerant African N'Dama (Bos taurus) and...


Hanotte, Olivier H.Ronin, Y.Agaba, MorrisNilsson, P.Gelhaus, A.Horstmann, R.Sugimoto, Y.Kemp, Stephen J.Gibson, John P.Korol, A.Soller, M.Teale, A.J.[Mapping of quantitative trait loci controlling trypanotolerance in a cross of tolerant West African N'Dama and susceptible East African Boran cattle]Mapping of quantitative trait loci controlling trypanotolerance in a cross of tolerant West African N'Dama and susceptible East African Boran cattle

To examine differences in cytokine profiles that may confer tolerance/susceptibility to bovine African trypanosomiasis, N'Dama (trypanotolerant, n = 8) and Boran (trypanosusceptible, n = 8) cattle were experimentally challenged with Trypanosoma congolense. Blood samples were collected over a 34-d...


O'Gorman, G.M.Park, S.D.E.Hill, E.W.Meade, K.G.Mitchell, L.C.Agaba, MorrisGibson, John P.Hanotte, Olivier H.Naessens, JanKemp, Stephen J.MacHugh, D.E.[Cytokine mRNA profiling of peripheral blood mononuclear cells from trypanotolerant and trypanosusceptible cattle infected with Trypanosoma congolense]Cytokine mRNA profiling of peripheral blood mononuclear cells from trypanotolerant and trypanosusceptible cattle infected with Trypanosoma congolense

In order to improve the conservation and sustainable utilization of the African catfish Clarias gariepinus of the Yala Swamp in Kenya, genetic diversity and population structure of Lakes Kanyaboli and Namboyo populations of the species were studied using DNA sequences of the mitochondrial D-loop ...


Barasa, J.E.Abila, R.Grobler, J.P.Agaba, MorrisChemoiwa, E.J.Kaunda-Arara, B.[High genetic diversity and population differentiation in Clarias gariepinus of Yala Swamp: Evidence from mitochondrial DNA sequences]High genetic diversity and population differentiation in Clarias gariepinus of Yala Swamp: Evidence from mitochondrial DNA sequences

Trypanosoma congolense is a protozoan parasite that causes severe diseases in livestock. Three major quantative trait loci (QTL), Tir1, Tir2, and Tir3, control the survival time of mice after infection with T. congolense. Congenic mice carrying the C57BL/6 resistance alleles on the A/J background...


Rathkolb, B.Noyes, H.A.Brass, A.Dark, P.Fuchs, H.Gailus-Durner, V.Gibson, John P.Angelis, M.H. deOgugo, M.Iraqi, F.A.Kemp, Stephen J.Naessens, JanPope, M.E.Wolf, E.Agaba, Morris[Clinical chemistry of congenic mice with quantitative trait loci for predicted responses to Trypanosoma congolense infection]Clinical chemistry of congenic mice with quantitative trait loci for predicted responses to Trypanosoma congolense infection

Trypanosoma congolense are extracellular protozoan parasites of the blood stream of artiodactyls and are one of the main constraints on cattle production in Africa. In cattle, anaemia is the key feature of disease and persists after parasitaemia has declined to low or undetectable levels, but tre...


Noyes, H.A.Alimohammadian, M.H.Agaba, MorrisBrass, A.Fuchs, H.Gailus-Durner, V.Hulme, H.Iraqi, F.A.Kemp, Stephen J.Rathkolb, B.Wolf, E.Angelis, M.H. deRoshandel, D.Naessens, Jan[Mechanisms controlling anaemia in Trypanosoma congolense infected mice]Mechanisms controlling anaemia in Trypanosoma congolense infected mice

Interspecies hybridization of bovids occurs between domestic cattle and at least three other species; American bison (Bison bison), yak (Bos grunniens) and banteng (Bos banteng). Birth of a cattle × buffalo (Bubalus bubalis) hybrid has reportedly occurred in Russia and in China, but these reports...


Owiny, O.D.Barry, D.M.Agaba, MorrisGodke, R.A.[In vitro production of cattle × buffalo hybrid embryos using cattle oocytes and African buffalo (Syncerus caffer caffer) epididymal sperm]In vitro production of cattle × buffalo hybrid embryos using cattle oocytes and African buffalo (Syncerus caffer caffer) epididymal sperm

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