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Four single-strand conformation variants of the bovine tumor necrosis factor alpha gene by analysis of PCR-amplified fragments were identified. The variants are inherited in Mendelian fashion and are informative for linkage mapping. We have mapped the bovine gene to Chromosome (Chr) 23 in a panel...


Agaba, MorrisKemp, Stephen J.Barendse, W.Teale, A.J.[Polymorphism at the bovine tumor necrosis factor alpha locus and assignment to BTA 23]Polymorphism at the bovine tumor necrosis factor alpha locus and assignment to BTA 23

Human chromosome (Chr) 18(HSA 18) contains approximately 85 million base pains of DNA. Thirty genes and pseudogenes have been mapped to HSA 18 by somatic cell genetics or in situ hybridization. Two bovine genes - Yamaguchi sacroma viral oncogene homology 1 (YESI) and desmocollin type 1 (DSC1) - h...


Agaba, MorrisKemp, Stephen J.Barendse, W.Teale, A.J.[Comparative mapping in cattle of genes located on human chromosome 18]Comparative mapping in cattle of genes located on human chromosome 18
Mujibi, F.D.N.Rao, E.J.O.Agaba, MorrisNyambo, D.Cheruiyot, E.K.Kihara, AbsolomonZhang, YiMrode, Raphael A.[Performance evaluation of highly admixed Tanzanian smallholder dairy cattle using SNP derived kinship matrix]Performance evaluation of highly admixed Tanzanian smallholder dairy cattle using SNP derived kinship matrix

African animal trypanosomiasis (AAT) caused by tsetse fly-transmitted protozoa of the genus Trypanosoma is a major constraint on livestock and agricultural production in Africa and is among the top ten global cattle diseases impacting on the poor. Here we show that a functional genomics approach ...


O'Gorman, G.M.Park, S. deHill, E.W.Meade, K.G.Coussens, P.M.Agaba, MorrisNaessens, JanKemp, Stephen J.MacHugh, D.E.[Transcriptional profiling of cattle infected with Trypanosoma congolense highlights gene expression signatures underlying trypanotolerance and trypanosusceptibility]Transcriptional profiling of cattle infected with Trypanosoma congolense highlights gene expression signatures underlying trypanotolerance and trypanosusceptibility
Namonyo, SamuelWagacha, M.Maina, SolomonWambua, L.Agaba, Morris[A metagenomic study of the rumen virome in domestic caprids]A metagenomic study of the rumen virome in domestic caprids

Indigenous goat breeds kept by majority of smallholder rural farmers in Eastern Africa are adapted to the local environment. These goats are critical for nutrition and income of their keepers. Milk production per doe is extremely variable. The variation in milk yield in goats is due to varied man...


Kiplagat, S.K.Agaba, MorrisKosgey, I.S.Okeyo Mwai, AllyIndetie, D.Hanotte, Olivier H.Limo, M.K.H.[Genetic polymorphism of kappa-casein gene in indigenous Eastern Africa goat populations]Genetic polymorphism of kappa-casein gene in indigenous Eastern Africa goat populations

A preliminary search for QTLs in a cattle F2 resource populations segregating for trypanotolerance has revealed three large candidate chromosomal regions (Bta02, Bta05, Bta07). In order to narrow down the position of the trypanotolerant QTLs, we are building comparative chromosomal maps between c...


Nilsson, P.H.Kang'a, S.Rottengatter, K.Suedbeck, U.Iraqui, F.Mwakaya, J.Mwangi, D.Womack, J.E.Goldammer, T.Schwerin, M.Bradley, D.Agaba, MorrisSugimoto, K.Gelhaus, A.Horstmann, R.Teale, A.J.Kemp, Stephen J.Hanotte, Olivier H.[Radiation hybrid maps of candidate trypanotolerance regions in cattle]Radiation hybrid maps of candidate trypanotolerance regions in cattle

Background: The history of African indigenous cattle and their adaptation to environmental and human selection pressure is at the root of their remarkable diversity. Characterization of this diversity is an essential step towards understanding the genomic basis of productivity and adaptation to s...


Kim, JaeminHanotte, Olivier H.Okeyo Mwai, AllyDessie, TadelleSalim, BashirDiallo, BoubacarAgaba, MorrisKwondo KimWoori KwakSamsun SungSeo, MinseokJeong, HyeonsooKwon, TaehyungTaye, MengistieSong, Ki-DukLim, DajeongSeoae ChoLee, Hyun-JeongDuhak YoonSung Jong OhKemp, Stephen J.Hak-Kyo LeeHeebal Kim[The genome landscape of indigenous African cattle]The genome landscape of indigenous African cattle

Cassava is an important root crop to resource-poor farmers in marginal areas, where its production faces drought stress constraints. Given the difficulties associated with cassava breeding, a molecular understanding of drought tolerance in cassava will help in the identification of markers for us...


Turyagyenda, L.F.Kizito, E.B.Ferguson, M.Baguma, Yona K.Agaba, MorrisHarvey, Jagger J.W.Osiru, D.S.O.[Physiological and molecular characterization of drought responses and identification of candidate tolerance genes in cassava]Physiological and molecular characterization of drought responses and identification of candidate tolerance genes in cassava
Muriuki, C.Bush, S.J.Salavati, M.McCulloch, M.E.B.Lisowski, Z.M.Agaba, MorrisDjikeng, AppolinaireHume, D.A.Clark, E.L.[A mini-atlas of gene expression for the domestic goat (Capra hircus)]A mini-atlas of gene expression for the domestic goat (Capra hircus)

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